Results 41 to 50 of about 123,987 (295)

Thyroid nodules treated with percutaneous radiofrequency thermal ablation: a comparative study [PDF]

, 2012
Percutaneous radiofrequency thermal ablation (RTA) was reported as an effective tool for the management of thyroid nodules (TNs). The aim of this study was to investigate the effects of RTA and to establish whether they were treatment-related by ...
Assanti, A P, Colao, A, Del Prete, M, Faggiano, A, Fonderico, F, Lombardi, G, Macchia, P E, Marciello, F, Marotta, V, Misso, C, Papini, E, Ramundo, V, Spiezia, S   +12 more
core   +1 more source

Hyperthyroidism in cats, part I : anatomy, physiology, pathophysiology, diagnosis and imaging [PDF]

, 2016
In the first part of this review article, thyroid anatomy, physiology and pathophysiology are reviewed to continue more specifically on hyperthyroidism, the most common thyroid disorder in cats.
Daminet, Sylvie, Peremans, Kathelijne, Saunders, Jimmy, Vandermeulen, Eva, Volckaert, Veerle   +4 more
core   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

Unstable Angina with Normal Coronary Angiography in Hyperthyroidism: A Case Report

Kaohsiung Journal of Medical Sciences, 2005
Hyperthyroidism is associated with an increase in myocardial oxygen consumption that, due to an imbalance of oxygen demand and supply, can cause angina. However, subclinical hyperthyroidism rarely presents as chest pain in the resting state.
Tsung-Hsien Lin, Ho-Ming Su, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu   +4 more
doaj   +1 more source

Hyperthyroidism in cats, part II : scintigraphic diagnosis and radioiodine treatment [PDF]

, 2016
In the second part of this review article, the diagnostic aspects of thyroid scintigraphy are discussed, with major emphasis on hyperthyroidism, followed by an overview of radioiodine ...
Daminet, Sylvie, Peremans, Kathelijne, Saunders, Jimmy, Vandermeulen, Eva, Volckaert, Veerle   +4 more
core   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

Reversible first-degree atrioventricular block due to hyperthyroidism

Türk Kardiyoloji Derneği Arşivi, 2017
Hyperthyroidism often causes tachyarrhythmia. Reversible atrioventricular block caused by hyperthyroidism is rare occurrence. Presently described is a case of atrioventricular block due to hyperthyroidism and recovery after antithyroid treatment.
Aksüyek Savaş Çelebi, Basri Amasyalı
doaj   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Epidemiology, prognosis, and challenges in the management of hyperthyroidism-related atrial fibrillation

European Thyroid Journal
Atrial fibrillation (AF) is a common condition with a global estimated prevalence of 60 million cases, and the most common cardiac complication of hyperthyroidism, occurring in 5–15% of overtly hyperthyroid patients.
Georgios Kostopoulos, Grigoris Effraimidis   +1 more
doaj   +1 more source

Integrating Photoredox and Anion‐Binding Capabilities into a Metal–Organic Cage for Iodine Speciation and Sequestration

Aggregate, EarlyView.
The environmental persistence and health risks associated with iodine species necessitate the development of innovative materials for precise iodine management. Here, a triazatriangulenium‐based coordination cage, combining structural stability, guest recognition, and photoredox activity, demonstrates significant potential to address challenges in ...
Ruiyu Guan, Jesper D. Jensen, Shihang Liang, Gen Li, Yawei Liu, Roy Lavendomme, Bo W. Laursen, En‐Qing Gao, Dawei Zhang   +8 more
wiley   +1 more source