Results 51 to 60 of about 128,736 (321)

Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation using antiarrhythmic drugs: An international cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert, Jenny Dimakos, Ying Cui, Kristian B. Filion, Christel Renoux, Antonios Douros   +5 more
wiley   +1 more source

Thyrotoxicosis: A paradox

Journal of Family Medicine and Primary Care, 2023
Incidence of thyroid dysfunctions including hypo- or hyperthyroidism is significantly increased. Hyperthyroidism is common in males, and hypothyroidism is often seen in females.
Himmatrao S. Bawaskar, Pramodini H. Bawaskar   +1 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Association between Noise Exposure and Hyperthyroidism Risk: A Retrospective Case-Control Study

Noise and Health
Background: Environmental and lifestyle factors may influence hyperthyroidism prevalence. This research sought to explore the association between noise exposure and the risk of hyperthyroidism. Methods: This retrospective case–control study was conducted
Ming Gao, Jianing Yi, Luyao Liu, Lin Xu
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans[S]

Journal of Lipid Research, 2014
Reduced plasma LDL-cholesterol is a hallmark of hyperthyroidism and is caused by transcriptional stimulation of LDL receptors in the liver. Here, we investigated whether thyroid hormone (TH) actions involve other mechanisms that may also account for the ...
Ylva Bonde, Olof Breuer, Dieter Lütjohann, Stefan Sjöberg, Bo Angelin, Mats Rudling   +5 more
doaj   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran, Mohammad Ali Omrani, Flory T. Muanda   +2 more
wiley   +1 more source

Artificial intelligence-enabled electrocardiography contributes to hyperthyroidism detection and outcome prediction

Communications Medicine
Background Hyperthyroidism is frequently under-recognized and leads to heart failure and mortality. Timely identification of high-risk patients is a prerequisite to effective antithyroid therapy.
Chin Lin, Feng-Chih Kuo, Tom Chau, Jui-Hu Shih, Chin-Sheng Lin, Chien-Chou Chen, Chia-Cheng Lee, Shih-Hua Lin   +7 more
doaj   +1 more source

Effect of Hyperthyroidism Treatments on Heart Rate Variability: A Systematic Review and Meta-Analysis

Biomedicines, 2022
The reversibility of HRV abnormalities in hyperthyroidism remains contradictory. The design of this study involves conducting a systematic review and meta-analysis on the effect of antithyroid treatments on HRV in hyperthyroidism.
Valentin Brusseau, Igor Tauveron, Reza Bagheri, Ukadike Chris Ugbolue, Valentin Magnon, Jean-Baptiste Bouillon-Minois, Valentin Navel, Frederic Dutheil   +7 more
doaj   +1 more source

Evaluation of Serum Symmetric Dimethylarginine Concentration as a Marker for Masked Chronic Kidney Disease in Cats With Hyperthyroidism

Journal of Veterinary Internal Medicine, 2018
Background Hyperthyroidism can complicate (mask) the diagnosis of chronic kidney disease (CKD) because it increases glomerular filtration rate and decreases body muscle mass, both of which can lower serum creatinine concentrations. Currently, there is no
Mark E Peterson, F. Varela, M. Rishniw, David J. Polzin   +3 more
semanticscholar   +1 more source