Results 171 to 180 of about 98,812 (291)

LDL particle size in familial combined hyperlipidemia: effects of serum lipids, lipoprotein-modifying enzymes, and lipid transfer proteins

Journal of Lipid Research, 2002
Small, dense LDL particles are typical for FCHL. Intravascular lipid exchange and net transfer among HDL, LDL, and triglyceride-rich lipoproteins as well as lipolysis in the VLDL-IDL-LDL cascade regulate properties of LDL.
Juha Vakkilainen, Matti Jauhiainen, Kati Ylitalo, Ilpo O. Nuotio, Jorma S.A. Viikari, Christian Ehnholm, Marja-Riitta Taskinen   +6 more
doaj  

Vascular reactivity and effect of serum in a rat model of hypertriglyceridemia and hypertension*1 [PDF]

, 1997
Guadalupe Baños
openalex   +1 more source

Immuno-virological and toxicity outcomes of HIV-infected patients after 48 months of ART in Phnom Penh, Cambodia [PDF]

, 2008
Mexico AIDS Conference ...
Balkan, Suna, Ferradini, Laurent, Moeung, S, Narom, P, Nerreniet, D, Nget, CC, Pinoges, Loretxu, Pujades-Rodriguez, M, Schramm, B, Som, L   +9 more
core   +1 more source

Expert Consensus on the Clinical Application of PI3K/AKT/mTOR Inhibitors in the Treatment of Breast Cancer (2025 Edition)

Cancer Innovation, Volume 4, Issue 3, June 2025.
ABSTRACT Background The phosphoinositide 3‐kinase (PI3K)/protein kinase B (PKB or AKT)/mammalian target of rapamycin (mTOR) signaling pathway (PAM pathway) plays a critical role in breast cancer pathogenesis and progression, and is closely linked with resistance to endocrine therapy in advanced breast cancer.
The Breast Cancer Expert Committee of the National Quality Control Center for Cancer, The Expert Committee on Cancer Prevention and Treatment of the Health China Research Center, The Society of Clinical Research on Oncology Medications of the China Anti‐Cancer Association, The Society of Onco‐Pathology of the China Anti‐Cancer Association   +3 more
wiley   +1 more source

AZ 242, a novel PPARα/γ agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats

Journal of Lipid Research, 2002
Abnormalities in fatty acid (333333333333382) metabolism underlie the development of insulin resistance and alterations in glucose metabolism, features characteristic of the metabolic syndrome and type 2 diabetes that can result in an increased risk of ...
Bengt Ljung, Krister Bamberg, Björn Dahllöf, Ann Kjellstedt, Nicholas D. Oakes, Jörgen Östling, Lennart Svensson, Germán Camejo   +7 more
doaj  

Effects of Omega‐3 Fatty Acids Intake on Lipid Metabolism and Plaque Volume in Patients With Coronary Heart Disease: A Systematic Review and Dose–Response Meta‐Analysis of Randomized Clinical Trials

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
Omega‐3 fatty acids supplementation significantly reduced circulating levels of triglycerides (TG) (standardized mean difference [SMD] = −0.25, 95% confidence interval [CI] = −0.38 to −0.11) and total cholesterol (TC) (SMD = −0.12, 95% CI = −0.23 to −0.02), with no significant impact on the levels of high‐density lipoprotein cholesterol (HDL‐C), low ...
Chunyu Zhang, Yulei Xie, Jie Zhou, Chun Zhang, Qilang Xiang, Yi Zhong, Juan Xiao, Jian Feng, Bin Liao, Xuxin Chen, Li Deng   +10 more
wiley   +1 more source

Antipeptide antibodies reveal interrelationships of MBP 200 and MBP 235: unique apoB-specific receptors for triglyceride-rich lipoproteins on human monocyte-macrophages

Journal of Lipid Research, 1999
Two human monocyte-macrophage (HMM) membrane binding proteins, (MBP) 200 and 235, are receptor candidates that bind to the apolipoprotein (apo)B-48 domain in triglyceride-rich lipoproteins for uptake independent of apoE.
William A. Bradley, Matthew L. Brown, M.P. Ramprasad, Ran Li, Ruiling Song, Sandra H. Gianturco   +5 more
doaj  

Activation of the Contact System of Coagulation Does Not Contribute to the Hemostatic Imbalance in Hypertriglyceridemia [PDF]

, 1999
Monique C. Minnema, M. E. Wittekoek, Niki S.M. Schoonenboom, J Kastelein, C. Erik Hack, Hugo Ten Cate   +5 more
openalex   +1 more source

Efficacy and safety of JMT103 in patients with bone metastases from solid tumors: A randomized Phase Ib clinical trial

International Journal of Cancer, Volume 156, Issue 11, Page 2178-2187, 1 June 2025.
What's new? Bone metastases are common in a variety of cancer types, causing increased pain and worse outcomes. Suppression of bone turnover, such as with the monoclonal antibody denosumab, results in fewer skeletal complications and improved prognosis. Here, the authors demonstrate the safety and efficacy of a similar antibody, JMT103. Like denosumab,
Ran Ran, Hongtao Li, Tao Sun, Huan Zhou, Aimin Zang, Hongqian Guo, Hua Xie, Shikai Wu, Yong Yan, Xing Yin, Hailin Xiong, Hong Li, Jing Yuan, Juan Wang, Huiping Li, Jin Li   +15 more
wiley   +1 more source

Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase

Journal of Lipid Research, 2008
GPIHBP1 is a glycosylphosphatidylinositol-anchored protein in the lymphocyte antigen 6 (Ly-6) family that recently was identified as a platform for the lipolytic processing of triglyceride-rich lipoproteins. GPIHBP1 binds both LPL and chylomicrons and is
Anne P. Beigneux, Peter Gin, Brandon S.J. Davies, Michael M. Weinstein, André Bensadoun, Robert O. Ryan, Loren G. Fong, Stephen G. Young   +7 more
doaj