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Familial hypertriglyceridemia [PDF]
The Indian Journal of Pediatrics, 2008 Familial hypertriglyceridemia (FHTG) is an uncommon primary (genetic) dyslipidemia. FHTG is characterized by moderately elevated serum triglycerides, usually in the absence of significant hypercholesterolemia and rarely manifests in childhood. We report an eight-month-old boy incidentally diagnosed as a case of FHTG due to lipemic serum (patient was ...
Shrinivas Tambe +3 more
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Endocrinology and Metabolism Clinics of North America, 2022
Mild to moderate hypertriglyceridemia usually results from multiple small-effect variants in genes that control triglyceride metabolism. Hypertriglyceridemia is a critical component of the metabolic syndrome but can also occur secondary to several other conditions or drugs.
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Mild to moderate hypertriglyceridemia usually results from multiple small-effect variants in genes that control triglyceride metabolism. Hypertriglyceridemia is a critical component of the metabolic syndrome but can also occur secondary to several other conditions or drugs.
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Current Opinion in Endocrinology, Diabetes & Obesity, 2022
Purpose of review Hypertriglyceridemia (HTG) is a risk factor for atherosclerotic cardiovascular disease (ASCVD), aortic stenosis, hepatic steatosis and pancreatitis. We briefly review the aetiology and treatment of HTG and familial chylomicronemia syndrome (FCS), as well as the implementation of a clinical quality registry for
Pang, J. +5 more
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Purpose of review Hypertriglyceridemia (HTG) is a risk factor for atherosclerotic cardiovascular disease (ASCVD), aortic stenosis, hepatic steatosis and pancreatitis. We briefly review the aetiology and treatment of HTG and familial chylomicronemia syndrome (FCS), as well as the implementation of a clinical quality registry for
Pang, J. +5 more
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Genomics of hypertriglyceridemia
2020With regard to heritability of phenotypes, the serum triglyceride level is considered to be highly heritable, with approximately 50% of its variability estimated to derive from parents. Thus, approximately 50% could be modifiable via environmental factors, including lifestyle and medications. Lipoproteins are definitive risk factors for atherosclerotic
Masa-aki Kawashiri +2 more
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Propranolol and hypertriglyceridemia
Atherosclerosis, 1973Abstract Eight subjects with elevated fasting plasma triglyceride levels and type IV hypertipoproteinemia, who received a 60 g fat meal before and after 2-week treatment with propranolol, showed an enhanced lipemic response to the meal after the treatment.
H. David Friedberg +3 more
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Pathophysiology of hypertriglyceridemia
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2012The importance of triglycerides as risk factor for CVD is currently under debate. The international guidelines do not include TG into their risk calculator despite the recent observations that plasma TG is an independent risk factor for CVD. The understanding of the pathophysiology of triglycerides opens up avenues for development of new drug targets ...
M. Nieuwdorp +5 more
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Treatment of hypertriglyceridemia
Current Diabetes Reports, 2006Hypertriglyceridemia is a disorder commonly encountered in clinical practice. Treatment of this condition aims to prevent the major complications of hypertriglyceridemia, which differ depending on whether triglyceride elevations are moderate or severe.
Warren H. Capell, Robert H. Eckel
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