Results 21 to 30 of about 98,812 (291)

Persistent hypertriglyceridemia in statin-treated patients with type 2 diabetes mellitus [PDF]

, 2013
Purpose: This paper reports the results of an audit that assessed the prevalence of residual hypertriglyceridemia and the potential need for intensified management among patients with statin-treated type 2 diabetes mellitus (T2DM) in primary care in the ...
Feher, Michael D., Greener, Mark, Munro, Neil   +2 more
core   +1 more source

An unexpected presentation of very severe hypertriglyceridemia in a boy with Coffin-Lowry syndrome: a case report

BMC Pediatrics, 2023
Background Coffin-Lowry syndrome (CLS) is a rare X-linked condition with intellectual disability, growth retardation, characteristic facies and skeletal anomalies.
Sue Lyn Tan, Muhammad Ghazali bin Ahmad Narihan, Ai Jiun Koa   +2 more
doaj   +1 more source

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

New England Journal of Medicine, 2019
BACKGROUND Patients with elevated triglyceride levels are at increased risk for ischemic events. Icosapent ethyl, a highly purified eicosapentaenoic acid ethyl ester, lowers triglyceride levels, but data are needed to determine its effects on ischemic ...
Deepak L. Bhatt, P. Steg, Michael Miller, E. Brinton, T. Jacobson, S. Ketchum, R. Doyle, R. Juliano, L. Jiao, C. Granowitz, J. Tardif, C. Ballantyne   +11 more
semanticscholar   +1 more source

Causes and Consequences of Hypertriglyceridemia

Frontiers in Endocrinology, 2020
Elevations in plasma triglyceride are the result of overproduction and impaired clearance of triglyceride-rich lipoproteins—very low-density lipoproteins (VLDL) and chylomicrons. Hypertriglyceridemia is characterized by an accumulation in the circulation
C. Packard, J. Borén, M. Taskinen
semanticscholar   +1 more source

The Genetic Basis of Hypertriglyceridemia

Current Atherosclerosis Reports, 2021
Hypertriglyceridemia is a common dyslipidemia associated with an increased risk of cardiovascular disease and pancreatitis. Severe hypertriglyceridemia may sometimes be a monogenic condition.
Germán D. Carrasquilla, Malene R Christiansen, T. Kilpeläinen   +2 more
semanticscholar   +1 more source

Genetics of Hypertriglyceridemia

Frontiers in Endocrinology, 2020
Hypertriglyceridemia, a commonly encountered phenotype in cardiovascular and metabolic clinics, is surprisingly complex. A range of genetic variants, from single-nucleotide variants to large-scale copy number variants, can lead to either the severe or ...
J. Dron, R. Hegele
semanticscholar   +1 more source

Therapy of Canine Hyperlipidemia with Bezafibrate. [PDF]

, 2017
BackgroundBezafibrate (BZF) is effective in the treatment of hypertriglyceridemia in human patients, but there are no data on its use in dogs.ObjectiveTo assess the safety of BZF in hyperlipidemic dogs and its efficacy in decreasing serum triglyceride ...
Casado, TC, De Marco, V, Florio, JC, Gilor, C, Nakandakare, ER, Noronha, KSM, Santos, EZ   +6 more
core   +1 more source

Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients. [PDF]

, 2017
Hypertriglyceridemia is an independent risk factor for cardiovascular disease. Apolipoprotein C-II (APOC2) is an obligatory cofactor for lipoprotein lipase (LPL), the major enzyme catalyzing plasma triglyceride hydrolysis.
Gaudet, Daniel, Liu, Chao, Miller, Yury I   +2 more
core   +1 more source

Severe hypertriglyceridemia in a subject with disturbed life style and poor glycemic control without recurrence of acute pancreatitis: a case report

BMC Endocrine Disorders, 2019
Background Hypertriglyceridemia is often observed as the result of lipid abnormality and frequently associated with other lipid and metabolic disorders. Aggravation of hypertriglyceridemia is caused by various conditions.
Shintaro Irie, Takatoshi Anno, Fumiko Kawasaki, Ryo Shigemoto, Shuhei Nakanishi, Kohei Kaku, Hideaki Kaneto   +6 more
doaj   +1 more source

The Correlation of Dyslipidemia with the Extent of Coronary Artery Disease in the Multiethnic Study of Atherosclerosis. [PDF]

, 2018
BackgroundThe extent of coronary artery calcium (CAC) improves cardiovascular disease (CVD) risk prediction. The association between common dyslipidemias (combined hyperlipidemia, simple hypercholesterolemia, metabolic Syndrome (MetS), isolated low high ...
Abd Alamir, Moshrik, Brown, Alan, Budoff, Mathew, Chaus, Adib, Dabbous, Firas, Goyfman, Michael, Sandfort, Veit, Tamura, Leslie   +7 more
core   +4 more sources