Results 21 to 30 of about 193,158 (291)

Targeted-Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy. [PDF]

Adv Sci (Weinh)
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Xing H, Zhao Z, Yang Y, Lin Y, Xuan Y, Wang Z, Lv K, Zhu X, Zhang Z, Ma D.   +9 more
europepmc   +2 more sources

Comparison of the effect of silicone gel sheets by thickness on excisional scars in pediatric and adolescent patients [PDF]

Archives of Aesthetic Plastic Surgery, 2022
Background Selecting effective products among the various types of silicone gel sheets can be challenging for surgeons. Therefore, we assessed the effect of silicone gel sheet thickness on surgical scars in pediatric and adolescent patients. Methods From
Min Ji Kim, Woo Beom Lee, Dong Ha Park
doaj   +1 more source

Hospital Procedural Volume and Clinical Outcomes Following Septal Reduction Therapy in Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Prior national data showed a substantial in‐hospital mortality in septal myectomy (SM) with an inverse volume–outcomes relationship. This study sought to assess the contemporary outcomes of septal reduction therapy and volume–outcome ...
Ahmed M. Altibi, Fares Ghanem, Yuanzi Zhao, Miriam Elman, Joaquin Cigarroa, Babak Nazer, Howard K. Song, Ahmad Masri   +7 more
doaj   +1 more source

Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy

Scientific Reports, 2021
Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM).
Styliani Vakrou, Yamin Liu, Li Zhu, Gabriela V. Greenland, Bahadir Simsek, Virginia B. Hebl, Yufan Guan, Kirubel Woldemichael, Conover C. Talbot, Miguel A. Aon, Ryuya Fukunaga, M. Roselle Abraham   +11 more
doaj   +1 more source

Hypertrophic cardiomyopathy: Totally a ST-elevation myocardial infarction mimic

Journal of the Practice of Cardiovascular Sciences, 2021
Hypertrophic cardiomyopathy (HCM) commonly presents with nonspecific ST-T changes in an electrocardiogram (EKG), and a paucity of literature description exists about index presentation of HCM totally as ST-elevation myocardial infarction (STEMI) in a ...
Debasish Das, Debasis Acharya, Tutan Das, Shashikant Singh, Jaideep Das Gupta, Subhas Pramanik   +5 more
doaj   +1 more source

Hypertrophic cardiomyopathy

IJC Heart & Vasculature, 2020
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease. The disease is characterized by marked variability in morphological expression and natural history, ranging from asymptomatic to heart failure or sudden cardiac death. Left ventricular hypertrophy and abnormal ventricular configuration result in dynamic left ventricular ...
Murillo de Oliveira Antunes, Thiago Luis Scudeler   +1 more
openaire   +3 more sources

The hypertrophic chondrocyte: To be or not to be.

Histology and histopathology, 2021
Hypertrophic chondrocytes are the master regulators of endochondral ossification; however, their ultimate cell fates cells remain largely elusive due to their transient nature. Historically, hypertrophic chondrocytes have been considered as the terminal state of growth plate chondrocytes, which are destined to meet their inevitable demise at the ...
Hallett, Shawn A., Ono, Wanida, Ono, Noriaki   +2 more
openaire   +2 more sources

Subcutaneous Implantable Cardioverter Defibrillator in Patients With Hypertrophic Cardiomyopathy: An Initial Experience

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe subcutaneous implantable cardioverter defibrillator (S‐ICD) has been developed to avert risks associated with transvenous defibrillator leads. The technology is attractive for younger patients, such as those with hypertrophic cardiomyopathy
Jonathan Weinstock, Yousef H. Bader, Martin S. Maron, Ethan J. Rowin, Mark S. Link   +4 more
doaj   +1 more source

Diffuse Fibrosis in Hypertrophic Cardiomyopathy

JACC: Advances
Background: Left ventricular (LV) myocardial extracellular volume (ECV), from cardiac magnetic resonance (CMR) T1 mapping, primarily reflects diffuse fibrosis and is a marker of adverse myocardial remodeling in hypertrophic cardiomyopathy (HCM ...
Susan K. Keen, MD, Hesham Sheashaa, MD, Stuti Shah, MD, Mohammed Abusafia, MD, Shada Jadam, MD, Simrat Kaur, MD, Andrew Gaballa, MD, Susan Ospina, NP, Katy Rutkowski, RN, Jay Ramchand, MD, PhD, Zoran B. Popovic, MD, PhD, Maran Thamilarasan, MD, Nicholas G. Smedira, MD, MBA, Paul Schoenhagen, MD, Michael Bolen, MD, Bo Xu, MD, Milind Y. Desai, MD, MBA   +16 more
doaj   +1 more source

Ménétrier's disease associated with ulcerative collitis [PDF]

Vojnosanitetski Pregled, 2003
In this paper a 21 year old patient was presented with Ménétrier's disease, associated with ulcerative colitis. The first symptoms of ulcerative colitis occured at the age of eleven, since when the patient has been conservatively treated several times ...
Mirković Darko, Doder Radoje, Ilić Srbislav, Mitrović Miroslav, Ignjatović Mile D.   +4 more
doaj   +1 more source