Results 11 to 20 of about 127,568 (322)

Hypertrophic Cardiomyopathy [PDF]

Cardiac Electrophysiology Clinics, 2010
Hypertrophic cardiomyopathy is a myocardial disease characterized by myocardial hypertrophy, disorganization of cardiac myocytes, and fibrosis. Twenty-five percent of patients have a dynamic left ventricular outflow tract gradient caused by the combined effects of rapid ventricular ejection, a narrowed outflow tract, and systolic anterior motion of the
Christopher, Critoph, Perry, Elliott
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Hypertrophic Cardiomyopathy

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2022
Hypertrophic cardiomyopathy (HCM) is a primary disease affecting the cardiac muscle and is characterized by heterogeneous genetic, morphological, functional and clinical features. The clinical presentation of HCM varies widely. Patients may be completely asymptomatic and identified incidentally.
Sarita Gore, Sunil Yogiraj Swami
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Hypertrophic Cardiomyopathy

Journal of Cardiovascular Development and Disease, 2023
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy resulting from a mutation in one of several cardiac sarcomeric proteins [...]
Asra K. Butt, Deya Alkhatib, Issa Pour-Ghaz, Sakiru Isa, Omar Al-Taweel, Ifeoma Ugonabo, Neeraja Yedlapati, John Lynn Jefferies   +7 more
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Clinical Outcomes in Patients With Nonobstructive, Labile, and Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundHypertrophic cardiomyopathy (HCM) is a common inherited cardiac disease characterized by varying degrees of left ventricular outflow tract obstruction. In a large cohort, we compare the outcomes among 3 different hemodynamic groups. Methods and
Dai‐Yin Lu, Iraklis Pozios, Bereketeab Haileselassie, Ioannis Ventoulis, Hongyun Liu, Lars L. Sorensen, Marco Canepa, Susan Phillip, M. Roselle Abraham, Theodore P. Abraham   +9 more
doaj   +1 more source

Sudden cardiac death in young athletes: Literature review of molecular basis [PDF]

, 2020
Intense athletic training and competition can rarely result in sudden cardiac death (SCD). Despite the introduction of pre-participation cardiovascular screening, especially among young competitive athletes, sport-related SCD remains a debated issue ...
Barbara Lombardo, Bruno Mirra, Cristina Mazzaccara, Ferdinando Barretta, Giulia Frisso, Olga Scudiero   +5 more
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Feline Hypertrophic Cardiomyopathy: A Spontaneous Large Animal Model of Human HCM. [PDF]

, 2017
Hypertrophic cardiomyopathy (HCM) is a common disease in pet cats, affecting 10-15% of the pet cat population. The similarity to human HCM, the rapid progression of disease, and the defined and readily determined endpoints of feline HCM make it an ...
Freeman, Lisa M, Huggins, Gordon S, Maron, Martin S, Rush, John E, Stern, Joshua A   +4 more
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Incremental Prognostic Utility of Left Ventricular Global Longitudinal Strain in Hypertrophic Obstructive Cardiomyopathy Patients and Preserved Left Ventricular Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundIn obstructive hypertrophic cardiomyopathy patients with preserved left ventricular (LV) ejection fraction, we sought to determine whether LV global longitudinal strain (LV‐GLS) provided incremental prognostic utility.
Albree Tower‐Rader, Jorge Betancor, Zoran B. Popovic, Kimi Sato, Maran Thamilarasan, Nicholas G. Smedira, Harry M. Lever, Milind Y. Desai   +7 more
doaj   +1 more source

Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy [PDF]

, 2010
BACKGROUND: Myocardial fibrosis is a hallmark of hypertrophic cardiomyopathy and a proposed substrate for arrhythmias and heart failure. In animal models, profibrotic genetic pathways are activated early, before hypertrophic remodeling.
Cirino, A.L. (Alison L.), Coelho-Filho, O.R. (Otavio R.), Colan, S.D. (Steven D.), Diez-Martinez, J. (Javier), Gonzalez, A. (Arantxa), Ho, C.Y. (Carolyn Y.), Jarolim, P. (Petr), Kwong, R.Y. (Raymond Y.), Lakdawala, N.K. (Neal K.), Lopez-Salazar, M.B. (María Begoña), Seidman, C.E. (Christine E.), Seidman, J.G. (J.G.)   +11 more
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Hypertrophic cardiomyopathy

IJC Heart & Vasculature, 2020
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease. The disease is characterized by marked variability in morphological expression and natural history, ranging from asymptomatic to heart failure or sudden cardiac death. Left ventricular hypertrophy and abnormal ventricular configuration result in dynamic left ventricular ...
Murillo de Oliveira Antunes, Thiago Luis Scudeler   +1 more
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A next-generation sequencing approach to identify gene mutations in early-and late-onset hypertrophic cardiomyopathy patients of an Italian cohort [PDF]

, 2016
Sequencing of sarcomere protein genes in patients fulfilling the clinical diagnostic criteria for hypertrophic cardiomyopathy (HCM) identifies a disease-causing mutation in 35% to 60% of cases.
Autore, Camillo, Bozzao, Cristina, Chessa, Luciana, Francia, Pietro, Germani, Aldo, Musumeci, Maria Beatrice, Pagannone, Erika, Pennacchini, Ermelinda, Piane, Maria, Rubattu, Speranza, Savio, Camilla, Volpe, Massimo   +11 more
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