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Current Treatment Options in Cardiovascular Medicine, 2002
When an individual is diagnosed with hypertrophic cardiomyopathy (HCM), all relatives potentially affected by Mendelian autosomal-dominant inheritance should be evaluated with an electrocardiogram (ECG) and echocardiogram. Genetic testing should be considered in high-risk mutations where there are diagnostic uncertainties.
Elijah R., Behr, William J., McKenna
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When an individual is diagnosed with hypertrophic cardiomyopathy (HCM), all relatives potentially affected by Mendelian autosomal-dominant inheritance should be evaluated with an electrocardiogram (ECG) and echocardiogram. Genetic testing should be considered in high-risk mutations where there are diagnostic uncertainties.
Elijah R., Behr, William J., McKenna
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The Lancet, 1998
Hypertrophic cardiomyopathy is a common genetically transmitted disease, defined clinically by the presence of unexplained left ventricular hypertrophy. The disease has a varied clinical course and outcome; many patients have little or no discernible cardiovascular symptoms, whereas others have profound exercise limitation and recurrent arrhythmias ...
Perry, Elliott, William J, McKenna
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Hypertrophic cardiomyopathy is a common genetically transmitted disease, defined clinically by the presence of unexplained left ventricular hypertrophy. The disease has a varied clinical course and outcome; many patients have little or no discernible cardiovascular symptoms, whereas others have profound exercise limitation and recurrent arrhythmias ...
Perry, Elliott, William J, McKenna
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Cardiology in the Young, 1977
AbstractHypertrophic cardiomyopathy is a common, inherited heart disease with a heterogeneous clinical presentation and natural history. Recently, advances in diagnosis and treatment options have been instrumental in decreasing the frequency of adverse clinical events; however, complete elimination of sudden cardiac death still remains an elusive gain.
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AbstractHypertrophic cardiomyopathy is a common, inherited heart disease with a heterogeneous clinical presentation and natural history. Recently, advances in diagnosis and treatment options have been instrumental in decreasing the frequency of adverse clinical events; however, complete elimination of sudden cardiac death still remains an elusive gain.
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Cardiology Clinics, 1988
Hypertrophic cardiomyopathy is a diverse clinical and pathophysiologic disorder of unknown cause that principally involves the left ventricle and is manifested as asymmetric or concentric hypertrophy. If asymmetric, the hypertrophy is usually greatest in the ventricular septum, but variations occur in which the hypertrophy may be maximal at the mid ...
Z, Sasson, H, Rakowski, E D, Wigle
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Hypertrophic cardiomyopathy is a diverse clinical and pathophysiologic disorder of unknown cause that principally involves the left ventricle and is manifested as asymmetric or concentric hypertrophy. If asymmetric, the hypertrophy is usually greatest in the ventricular septum, but variations occur in which the hypertrophy may be maximal at the mid ...
Z, Sasson, H, Rakowski, E D, Wigle
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Pacing and Clinical Electrophysiology, 2009
Background: Hypertrophic cardiomyopathy (HCM) is one of the most common inherited cardiac disorders, with a prevalence in young adults of one in 500 and is defined by its wall thickening. Methods: This chapter of the supplement will present major clinical impacts of this disorder in its predilection to be inherited; its ...
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Background: Hypertrophic cardiomyopathy (HCM) is one of the most common inherited cardiac disorders, with a prevalence in young adults of one in 500 and is defined by its wall thickening. Methods: This chapter of the supplement will present major clinical impacts of this disorder in its predilection to be inherited; its ...
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Anesthesia & Analgesia, 2015
Hypertrophic cardiomyopathy (HCM) is a relatively common disorder that anesthesiologists encounter among patients in the perioperative period. Fifty years ago, HCM was thought to be an obscure disease. Today, however, our understanding and ability to diagnose patients with HCM have improved dramatically.
Nadia, Hensley +5 more
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Hypertrophic cardiomyopathy (HCM) is a relatively common disorder that anesthesiologists encounter among patients in the perioperative period. Fifty years ago, HCM was thought to be an obscure disease. Today, however, our understanding and ability to diagnose patients with HCM have improved dramatically.
Nadia, Hensley +5 more
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Acta Pharmacologica et Toxicologica, 1986
Abstract: Hypertrophic cardiomyopathy is characterized by a hypertrophic and non‐dilated left ventricle with disproportionate involvement of the intraventricular septum compared to the free walls, and by varying degrees of outflow obstruction during systole. Its symptoms and clinical course, pathogenesis and treatment are briefly discussed.
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Abstract: Hypertrophic cardiomyopathy is characterized by a hypertrophic and non‐dilated left ventricle with disproportionate involvement of the intraventricular septum compared to the free walls, and by varying degrees of outflow obstruction during systole. Its symptoms and clinical course, pathogenesis and treatment are briefly discussed.
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Hypertrophic cardiomyopathy in children
Heart, 2012Hypertrophic cardiomyopathy (HCM) is the second commonest form of heart muscle disease affecting children and adolescents and is a leading cause of sudden death in young athletes. The aetiology of HCM is heterogeneous in the paediatric population, and includes inborn errors of metabolism, neuromuscular disorders and malformation syndromes.
Jeffrey P, Moak, Juan Pablo, Kaski
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Hypertrophic Cardiomyopathy and Pregnancy
Cardiology in ReviewHypertrophic cardiomyopathy (HCM) is an autosomal dominant inherited disease characterized by left ventricular hypertrophy, progressive diastolic dysfunction, left ventricular outflow obstruction, ventricular arrhythmias, and sudden death. Due to widespread screening and early diagnosis, there is a growing number of women of reproductive age with HCM ...
Amha Weldehana +4 more
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