Results 251 to 260 of about 125,690 (294)

R405W Desmin Knock‐In Mice Highlight Alterations of Mitochondria, Protein Quality Control and Myofibrils in Myofibrillar Myopathy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Mutations in the desmin gene cause skeletal myopathies and cardiomyopathies. The objective of this study was to elucidate the molecular pathology induced by the expression of R405W mutant desmin in murine skeletal muscle. Methods A comprehensive characterization of the skeletal muscle pathology in hetero‐ and homozygous R405W desmin
Sabrina Batonnet‐Pichon   +19 more
wiley   +1 more source

Exploring Morphologic and Functional Variants in Hypertrophic Cardiomyopathy: An Echocardiographic and Doppler Review. [PDF]

open access: yesDiagnostics (Basel)
Stankowski K   +14 more
europepmc   +1 more source

Cardiovascular genetic counselor decision making about discussing life insurance with patients

open access: yesJournal of Genetic Counseling, Volume 34, Issue 6, December 2025.
Abstract Genetic counselors (GCs) educate patients about the benefits, risks, and limitations of genetic testing. The regulatory environment governing the use of genetic data in life insurance is not uniform internationally or within the United States (US).
Sara Cherny   +4 more
wiley   +1 more source

Hydroxychloroquine Cardiotoxicity and Sarcomeric Hypertrophic Cardiomyopathy. [PDF]

open access: yesJACC Case Rep
Averbuch T   +5 more
europepmc   +1 more source

Reduced Kidney Function and Left Atrial Dilatation as Predictors of Incident Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy

open access: yesJournal of Arrhythmia, Volume 41, Issue 6, December 2025.
New‐onset atrial fibrillation (AF) occurred in 22% of patients with hypertrophic cardiomyopathy, corresponding to an incidence rate of 2.8 per 100 person‐years. Reduced kidney function and left atrial dilatation were independently associated with AF onset, indicating the need for closer monitoring and regular renal assessments in this population ...
Yuriko Tsumaya   +21 more
wiley   +1 more source

Apical Hypertrophic Cardiomyopathy: Diagnostic Challenges in a Patient with Hypertension and Obstructive Sleep Apnea. [PDF]

open access: yesAm J Case Rep
Llerena-Velastegui J   +4 more
europepmc   +1 more source

Clinical and pathological findings in giraffes (Giraffa camelopardalis) with arterial thrombotic disease

open access: yesVeterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract Two adult female giraffes (Giraffa camelopardalis) from separate facilities were diagnosed with arterial thrombotic disease. The first giraffe presented with acute severe unilateral hindlimb paralysis. Infrared thermography revealed a marked temperature decrease compared to the contralateral limb starting from the mid‐thigh region, indicative ...
Pierre Huberdeau   +7 more
wiley   +1 more source

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