Results 271 to 280 of about 282,907 (338)

Cardiac fibrosis induced by high‐fat diet in ApoE‐deficient male mice is exacerbated by genetic deletion of PACAP–PAC1 signaling

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Cardiac fibrosis is characterized by an excessive accumulation of extracellular matrix proteins and occurs in a variety of cardiac diseases, such as the highly prevalent syndrome heart failure with preserved ejection fraction (HFpEF) and other cardiac disorders.
J. M. Schubart   +11 more
wiley   +1 more source

Hypertension in Patients With Obstructive Hypertrophic Cardiomyopathy Treated With Mavacamten. [PDF]

open access: yesJACC Heart Fail
Reza N   +9 more
europepmc   +1 more source

Left Ventricular Sarcoma Causing Dynamic Outflow Tract Obstruction and Cardiogenic Shock: A Case Report

open access: yesCase Reports in Critical Care, Volume 2026, Issue 1, 2026.
Background Primary cardiac sarcomas are rare and aggressive tumors that often present with nonspecific symptoms, typically diagnosed at advanced stages. Obstruction of the left ventricular outflow tract (LVOT) due to these tumors is an exceptionally rare and life‐threatening complication.
Tomás de la Barra   +8 more
wiley   +1 more source

Echocardiographic Mitral Valve Fibroelastoma in a Patient With Hypertrophic Cardiomyopathy. [PDF]

open access: yesJACC Case Rep
Le Q   +6 more
europepmc   +1 more source

Identification of Two Rare Variants in Iranian Families With Familial Sudden Cardiac Death

open access: yesInternational Journal of Genomics, Volume 2026, Issue 1, 2026.
Cellular action potential is characterized by a particular sequence of depolarizing and repolarizing ion currents regulated by ion channels. Genetic mutations in these channels disrupt the essential movement of ions, such as Na+, Ca++, and K+, across the cell membrane, leading to dangerous arrhythmias and sudden cardiac death (SCD).
Mahsa Tahmasebivand   +10 more
wiley   +1 more source

Yixiao Formula Suppresses Myocardial Fibrosis Through UpregulatingmiR‐133a and Downregulating TGF‐β/Smads Signal Molecules

open access: yesJournal of Diabetes Research, Volume 2026, Issue 1, 2026.
Background Yixiao formula (YXF), a traditional Chinese herbal medicine, has demonstrated clinical efficacy in alleviating symptoms of diabetic cardiomyopathy (DCM). The therapeutic mechanism underlying YXF′s effects on DCM remains poorly understood. Myocardial fibrosis is a key pathogenic mechanism in DCM, and previous studies have indicated that miR ...
Qiyao Zhao   +11 more
wiley   +1 more source

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