Results 41 to 50 of about 222,830 (234)

Case Report: Minimally Invasive Therapy by Transcatheter Aortic Valve Replacement and Percutaneous Intramyocardial Septal Radiofrequency Ablation for a Patient With Aortic Stenosis Combined With Hypertrophic Obstructive Cardiomyopathy: Two-Year Follow-Up Results

Frontiers in Cardiovascular Medicine, 2021
With the development of minimally invasive technologies in the medical field, more and more technologies can replace surgical thoracotomy and relieve the pain of disease via minimally invasive methods. We reported a case of aortic valve stenosis combined
Yijian Li, Yuan Feng, Xi Li, Lei Zuo, Tao Gu, Liwen Liu, Mao Chen   +6 more
doaj   +1 more source

Disopyramide Revisited for Treatment of Symptomatic Obstructive Hypertrophic Cardiomyopathy: Efficacy and Safety in Patients Treated for at Least 5 Years

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Disopyramide is used to treat heart failure symptoms in patients with obstructive hypertrophic cardiomyopathy (HCM) with known medium‐term efficacy and safety, while long‐term outcomes are unknown. Methods and Results A total of 92 consecutive
Daniele Massera, Mark V. Sherrid, Elizabeth Adlestein, Nadia Bokhari, Isabel C. Alvarez, Woon Y. Wu, Maria C. Reuter, Martin S. Maron, Barry J. Maron, Ethan J. Rowin   +9 more
doaj   +1 more source

Differences in microRNA-29 and Pro-fibrotic Gene Expression in Mouse and Human Hypertrophic Cardiomyopathy

Frontiers in Cardiovascular Medicine, 2019
Background: Hypertrophic cardiomyopathy (HCM) is characterized by myocyte hypertrophy and fibrosis. Studies in two mouse models (R92W-TnT/R403Q-MyHC) at early HCM stage revealed upregulation of endothelin (ET1) signaling in both mutants, but TGFβ ...
Yamin Liu, Yamin Liu, Junaid Afzal, Junaid Afzal, Styliani Vakrou, Gabriela V. Greenland, Gabriela V. Greenland, C. Conover Talbot, Virginia B. Hebl, Yufan Guan, Rehan Karmali, Jil C. Tardiff, Leslie A. Leinwand, Jeffrey E. Olgin, Samarjit Das, Ryuya Fukunaga, M. Roselle Abraham, M. Roselle Abraham   +17 more
doaj   +1 more source

[2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy].

Kardiologia polska, 2014
© 2015, Silicea-Poligraf. All Rights Reserved. The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC).
Perry M. Elliott, A. Anastasakis, M. Borger, Martin Borggrefe, F. Cecchi, P. Charron, A. Hagège, A. Lafont, Giuseppe Limongelli, H. Mahrholdt, W. McKenna, J. Mogensen, P. Nihoyannopoulos, S. Nistri, P. Pieper, B. Pieske, C. Rapezzi, F. Rutten, Christoph Tillmanns, Hugh Watkins   +19 more
semanticscholar   +1 more source

Clinical course and outcomes in adults with co-occurring hypertrophic cardiomyopathy and hypertension: a scoping review protocol

BMJ Open, 2023
Introduction Hypertension affects 40%–60% of adults with hypertrophic cardiomyopathy (HCM), the most common inherited cardiac condition. It can be a diagnostic confounder for HCM, contributing to delayed diagnosis.
Daniele Massera, Daichi Shimbo, Sophie Montgomery, Milla Arabadjian, Barnaby Nicolas, Mitchell Pleasure, Maxine Collins, Maria Reuter, Mark Sherrid   +8 more
doaj   +1 more source

Echocardiographic Changes Following Surgical Myectomy in Severely Symptomatic Obstructive Hypertrophic Cardiomyopathy: Insights From the SPIRIT‐HCM Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In obstructive hypertrophic cardiomyopathy, myectomy improves symptoms, quality of life, and left ventricular (LV) outflow tract gradients. We prospectively evaluated the temporal changes in various echo parameters after myectomy.
Milind Y. Desai, Natalie Szpakowski, Albree Tower‐Rader, Barb Bittel, Agostina Fava, Susan Ospina, Bo Xu, Maran Thamilarasan, Amgad Mentias, Nicholas G. Smedira, Zoran B. Popovic   +10 more
doaj   +1 more source

Machine Learning for Predicting Heart Failure Progression in Hypertrophic Cardiomyopathy

Frontiers in Cardiovascular Medicine, 2021
Background: Development of advanced heart failure (HF) symptoms is the most common adverse pathway in hypertrophic cardiomyopathy (HCM) patients. Currently, there is a limited ability to identify HCM patients at risk of HF.Objectives: In this study, we ...
Ahmed S. Fahmy, Ethan J. Rowin, Warren J. Manning, Warren J. Manning, Martin S. Maron, Reza Nezafat   +5 more
doaj   +1 more source

Deep learning approach to left ventricular non-compaction measurement [PDF]

arXiv, 2020
Left ventricular non-compaction (LVNC) is a rare cardiomyopathy characterized by abnormal trabeculations in the left ventricle cavity. Although traditional computer vision approaches exist for LVNC diagnosis, deep learning-based tools could not be found in the literature.
arxiv  

Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes

Circulation Genomic and Precision Medicine, 2019
Background: Genetic testing for families with hypertrophic cardiomyopathy (HCM) provides a significant opportunity to improve care. Recent trends to increase gene panel sizes often mean variants in genes with questionable association are reported to ...
J. Ingles, J. Goldstein, C. Thaxton, C. Caleshu, Edward W. Corty, Stephanie B. Crowley, Kristen Dougherty, S. Harrison, Jennifer L McGlaughon, L. Milko, A. Morales, Bryce A. Seifert, Natasha T. Strande, K. Thomson, J. Peter van Tintelen, Kathleen E. Wallace, R. Walsh, Q. Wells, N. Whiffin, L. Witkowski, C. Semsarian, J. Ware, R. Hershberger, B. Funke   +23 more
semanticscholar   +1 more source

Real-World Data Analysis of Implantable Cardioverter Defibrillator (ICD) in Patients with Hypertrophic Cardiomyopathy (HCM) [PDF]

arXiv, 2020
Background: One of the common causes of sudden cardiac death (SCD) in young people is hypertrophic cardiomyopathy (HCM) and the primary prevention of SCD is with an implantable cardioverter defibrillators (ICD). Concerning the incidence of appropriate ICD therapy and the complications associated with ICD implantation and discharge, patients with ...
arxiv