Results 51 to 60 of about 70,031 (333)
A Generalizable Deep Learning System for Cardiac MRI [PDF]
arXiv, 2023 Cardiac MRI allows for a comprehensive assessment of myocardial structure, function, and tissue characteristics. Here we describe a foundational vision system for cardiac MRI, capable of representing the breadth of human cardiovascular disease and health.
arxiv
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson +10 more
wiley +1 more source
Journal of Peptide Science, Volume 29, Issue 2, February 2023., 2023 An epitope located at the C‐terminal end of calsperin corresponding to amino acids 228WEKHFLDAS237 was identified by using two monoclonal antibodies and resin‐bound calsperin peptides. Three hot spot amino acids were essential for antibody binding.
Ann Christina Bergmann +2 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundEchocardiography-guided percutaneous intramyocardial alginate-hydrogel implantation (PIMAHI) is a novel treatment approach for heart failure (HF).
Hui Ma +8 more
doaj +1 more source
Anatolian Journal of Cardiology, 2023 Background: Hypertrophic cardiomyopathy is a common genetic heart disease and up to 40%-60% of patients have mutations in cardiac sarcomere protein genes.
Veysel Oktay +36 more
doaj +1 more source
Real-World Data Analysis of Implantable Cardioverter Defibrillator (ICD) in Patients with Hypertrophic Cardiomyopathy (HCM) [PDF]
arXiv, 2020 Background: One of the common causes of sudden cardiac death (SCD) in young people is hypertrophic cardiomyopathy (HCM) and the primary prevention of SCD is with an implantable cardioverter defibrillators (ICD). Concerning the incidence of appropriate ICD therapy and the complications associated with ICD implantation and discharge, patients with ...
arxiv
Management of hypertrophic cardiomyopathy [PDF]
BMJ, 2006 Hypertrophic cardiomyopathy is the most common familial genetic disease of the heart (1/500 to 1/1000), as well as the most common cause of sudden cardiac death in young people and athletes. Because a timely diagnosis may help to prevent sudden death, it is important for internists and general practitioners to be aware of the clinical features of the ...
P. Spirito, AUTORE, Camillo
openaire +4 more sources
CRISPR applications for Duchenne muscular dystrophy: From animal models to potential therapies
WIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023 CRISPR‐Cas9 gene‐editing technology enables the rapid generation of animal models for Duchenne muscular dystrophy research and has potential to be developed as CRISPR therapy for the long lasting genetic correction of causal mutations. Abstract CRISPR gene‐editing technology creates precise and permanent modifications to DNA.
Yu C. J. Chey +4 more
wiley +1 more source
Weight loss in hypertrophic cardiomyopathy: A clinical case series
International Journal of Cardiology. Cardiovascular Risk and Prevention, 2023 Background: Obesity is prevalent among patients with hypertrophic cardiomyopathy (HCM). Obese HCM patients have greater wall thickness, LV mass, worse hemodynamic function and NYHA class. Weight loss may favorably influence the HCM phenotype.
Maria C. Reuter +6 more
doaj
PLoS ONE, 2021 AimsArrhythmia mechanisms in hypertrophic cardiomyopathy remain uncertain. Preclinical models suggest hypertrophic cardiomyopathy-linked mutations perturb sarcomere length-dependent activation, alter cardiac repolarization in rate-dependent fashion and ...
Andrew E Radbill +7 more
doaj +1 more source