Results 81 to 90 of about 222,830 (234)

Computational analysis of folding and mutation properties of C5 domain from Myosin binding protein C [PDF]

arXiv, 2007
Thermal folding Molecular Dynamics simulations of the domain C5 from Myosin Binding Protein C were performed using a native-centric model to study the role of three mutations related to Familial Hypertrophic Cardiomyopathy. Mutation of Asn755 causes the largest shift of the folding temperature, and the residue is located in the CFGA' beta-sheet ...
arxiv  

Myocardial constructive work is impaired in hypertrophic cardiomyopathy and predicts left ventricular fibrosis

Echocardiography, 2018
The estimation of myocardial work by pressure strain loops (PSLs) is a totally new non‐invasive approach to assess myocardial performance, and its role in patients with hypertrophic cardiomyopathy is unknown. The aims of the present study are therefore: (
E. Galli, Emilie Vitel, F. Schnell, V. Le Rolle, A. Hubert, M. Lederlin, E. Donal   +6 more
semanticscholar   +1 more source

Is Hypertrophic Cardiomyopathy Always a Familial and Inherited Disease?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Jiri Bonaventura, Ethan J. Rowin, Martin S. Maron, Barry J. Maron   +3 more
doaj   +1 more source

Feature Tracking Cardiac Magnetic Resonance via Deep Learning and Spline Optimization [PDF]

arXiv, 2017
Feature tracking Cardiac Magnetic Resonance (CMR) has recently emerged as an area of interest for quantification of regional cardiac function from balanced, steady state free precession (SSFP) cine sequences. However, currently available techniques lack full automation, limiting reproducibility.
arxiv  

Myosin Inhibition in Patients With Obstructive Hypertrophic Cardiomyopathy Referred for Septal Reduction Therapy.

Journal of the American College of Cardiology, 2022
M. Desai, A. Owens, J. Geske, K. Wolski, S. Naidu, N. Smedira, P. Cremer, H. Schaff, E. McErlean, Christina Sewell, Wanying Li, Lulu Sterling, K. Lampl, J. Edelberg, A. Sehnert, S. Nissen   +15 more
semanticscholar   +1 more source

Diffuse interstitial fibrosis assessed by cardiac magnetic resonance is associated with dispersion of ventricular repolarization in patients with hypertrophic cardiomyopathy

Journal of Arrhythmia, 2017
Background: Hypertrophic cardiomyopathy (HCM) is characterized by myocyte hypertrophy, disarray, fibrosis, and increased risk for ventricular arrhythmias.
David Hurtado-de-Mendoza, MD, Celia P. Corona-Villalobos, MD, Iraklis Pozios, MD, Jorge Gonzales, MD, Yalda Soleimanifard, MD, Sanjay Sivalokanathan, MD, Diego Montoya-Cerrillo, MD, Styliani Vakrou, MD, Ihab Kamel, MD, Wilfredo Mormontoy-Laurel, MD, Ketty Dolores-Cerna, MD, Jacsel Suarez, MD, Sergio Perez-Melo, MD, David A. Bluemke, MD, Theodore P. Abraham, MD, Stefan L. Zimmerman, MD, M. Roselle Abraham, MD   +16 more
doaj   +1 more source

Hypertrophic cardiomyopathy [PDF]

Current Problems in Cardiology, 1993
Maron, B J, McKenna, W J, Elliott, P, Spirito, P, Frenneaux, M P, Keren, A, Cecchi, F, Borggrefe, M, Williams, W G   +8 more
openaire   +7 more sources

Management of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review.

Journal of the American College of Cardiology, 2022
B. Maron, M. Desai, R. Nishimura, P. Spirito, H. Rakowski, J. Towbin, J. Dearani, E. Rowin, M. Maron, M. Sherrid   +9 more
semanticscholar   +1 more source

Learning Interpretable Anatomical Features Through Deep Generative Models: Application to Cardiac Remodeling [PDF]

arXiv, 2018
Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as manual analysis of medical images.
arxiv  

Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity

Nature Genetics, 2021
A. Harper, A. Goel, C. Grace, K. Thomson, Steffen Erhard Petersen, Xiao Xu, A. Waring, E. Ormondroyd, C. Kramer, Carolyn Y. Ho, S. Neubauer, Paul Raymond Sarahfaye F. Patrice John P. Nancy Dong-Yu Kolm Kwong Dolman Desvigne-Nickens Dimarco Geller , P. Kolm, Raymond Kwong, S. Dolman, P. Desvigne‐Nickens, J. Dimarco, Nancy Geller, Dong-Yun Kim, Cheng Zhang, W. Weintraub, T. Abraham, Lisa Anderson, E. Appelbaum, C. Autore, C. Berry, E. Biagini, W. Bradlow, C. Bucciarelli-Ducci, A. Chiribiri, L. Choudhury, A. Crean, D. Dawson, M. Desai, E. Elstein, A. Flett, Matthias Friedrich, S. Heitner, Adam Helms, Daniel L. Jacoby, Han Kim, Bette Kim, É. Larose, M. Mahmod, H. Mahrholdt, M. Maron, Gerry McCann, M. Michels, Saidi A Mohiddin, Sherif F Nagueh, D. Newby, I. Olivotto, A. Owens, F. Pierre-Mongeon, S. Prasad, O. Rimoldi, M. Salerno, J. Schulz-Menger, M. Sherrid, P. Swoboda, A. van Rossum, J. Weinsaft, J. White, Eric Williamson, R. Tadros, J. Ware, C. Bezzina, M. Farrall, H. Watkins   +68 more
semanticscholar   +1 more source