Results 81 to 90 of about 71,425 (202)

Hypertrophic cardiomyopathy [PDF]

Current Problems in Cardiology, 1993
openaire   +3 more sources

Molecular genetics of arrhythmogenic right ventricular cardiomyopathy in South Africa

, 2011
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable disorder characterised by progressive degeneration of the right ventricular myocardium, arrhythmias and an increased risk of sudden death at a young age. Fourteen chromosomal loci have
Blanckenberg, Janine
core  

Efficacy and safety of myosin inhibitors for symptomatic hypertrophic cardiomyopathy: systematic review and meta-analysis

Introduction Hypertrophic cardiomyopathy (HCM) is a common genetic cardiac disorder associated with significant morbidity and mortality. Cardiac myosin inhibitors (MIs), including mavacamten and aficamten, offer a novel therapeutic approach for HCM ...
Sunam Kafle, Abdul Rasheed Bahar, M. Chadi Alraies, Sameer Lohana, Jasgit Bhinder, Kunal N. Patel, Jawad Basit, Jared Kvapil, Mohammad Hazique   +8 more
core   +1 more source

Ventricular arrhythmias complicating hypertrophic cardiomyopathy

, 2012
Hypertrophic cardiomyopathy is the most common genetic cardiovascular disorder and the leading cause of sudden cardiac death in the young. This article reviews the ventricular arrhythmias associated with hypertrophic cardiomyopathy, the difficulties in ...
Venetucci, Luigi, Sankaranarayanan, Rajiv, Hutchings, David; id_orcid   +2 more
core   +2 more sources

Hypertrophic cardiomyopathy

, 2016
Hypertrophic cardiomyopathy is discussed in view of data on genetic background. Differential diagnosis and risk stratification, and recommendations on therapy by the ACC/AHA and ESC are presented.
Bernard J. Gersh, Demosthenes G. Katritsis, A. John Camm   +2 more
core   +1 more source

Allele-specific dysregulation of lipid and energy metabolism in early-stage hypertrophic cardiomyopathy

Journal of Molecular and Cellular Cardiology Plus
Introduction: Hypertrophic cardiomyopathy (HCM) results from pathogenic variants in sarcomeric protein genes that increase myocyte energy demand and lead to cardiac hypertrophy.
Arpana Vaniya, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, M. Roselle Abraham   +11 more
doaj   +1 more source

New perspectives in Hypertrophic Cardiomyopathy [PDF]

, 1998
Hypertrophic cardiomyopathy is a primary cardiac disorder with a heterogeneous expression. Although relatively uncommon, the disease has been studied extensively as appears from the numerous studies that have explored specific facets of hypertrophic ...
Kofflard, MJM, Kofflard, M.J.M. (Marcel)
core   +1 more source

Complete Heart Block in Hypertrophic Cardiomyopathy: A Rare Association

, 2017
Ventricular tachyarrhythmias are common in hypertrophic cardiomyopathy that may lead to syncope and sudden death. Bradyarrhythmia such as atrioventricular conduction disturbance, a relatively rare complication associated with hypertrophic cardiomyopathy,
L. Dubey, G. Subramanyam, S. Guruprasad, R. Battacharya   +3 more
core   +1 more source

Genetics of cardiomyopathies: hypertrophic cardiomyopathy

, 2018
Hypertrophic cardiomyopathy is characterized by the presence of increased left ventricular wall thickness that is not solely explained by abnormal loading conditions (such as hypertension or valvular disease).
Carole Maupain, Philippe Charron
core   +1 more source

Natural products targeting regulated cell deaths for adriamycin-induced cardiotoxicity

Cell Death Discovery
Adriamycin (ADR), as an anti-cancer drug in routine clinical application, is utilized to treat various cancers such as ovarian cancer, hematological malignant tumor, and endometrial carcinoma.
Zheng Wang, Yanli Zhu, Yu Yao, Wenyu Zhang, Bo Wang, Jing Wang, Yang Yang, Liwen Liu   +7 more
doaj   +1 more source