Results 151 to 160 of about 23,884 (245)

Predictors and Outcomes of Pharmacological and Electrical Cardioversion for Atrial Fibrillation and Flutter in an Indian Emergency Department: A Retrospective Study

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
In a real‐world emergency department study of atrial fibrillation and flutter, cardioversion restored sinus rhythm in 68% of patients. Electrical cardioversion achieved the highest success, while pharmacological and mixed strategies predicted failure. Complications were infrequent but clinically significant.
Abid M. Sadiq   +3 more
wiley   +1 more source

Mavacamten’s therapeutic impact: cardiac-specific myosin inhibition in obstructive hypertrophic cardiomyopathy

open access: yesGlobal Cardiology
Dear Editor, Obstructive hypertrophic cardiomyopathy (oHCM) is a hereditary cardiac condition, affecting 1 in about 500 individuals, characterized by an atypical thickening of the heart muscle, specifically the interventricular septum...
Ahmad Shabbir, Laiba Yumn, Esha Khan
doaj   +1 more source

Clinical and genetic characterization of patients with hypertrophic cardiomyopathy and right atrial enlargement [PDF]

open access: yes, 2016
AIMS: Prevalence and clinical significance of right atrial enlargement (RAE) has been poorly characterized in hypertrophic cardiomyopathy. METHODS: One hundred and sixty consecutive patients with hypertrophic cardiomyopathy (35.5 ± 20 years; 64% men ...
Bossone, E   +11 more
core  

Single‐Cell and Spatial Omics: Methods and Applications

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Systematically summarized the breakthrough sequencing technologies and computational methods for single‐cell and spatial omics across multiple omics layers, including genome, epigenome, transcriptome, proteome, and metabolome. State‐of‐the‐art methods for multi‐omics integration, cross‐modal integration, and cross‐scale integration were reviewed, with ...
Xiaoping Cen   +10 more
wiley   +1 more source

Added Value of Rotational Mechanics to Longitudinal Indices in the Risk Stratification of Patients With Left Ventricular Hypertrophy

open access: yesEchocardiography, Volume 43, Issue 4, April 2026.
The present study shows how 2D‐speckle tracking echocardiographic measures of myocardial rotational mechanics provide valuable information about the LVEF spectrum in patients with left ventricular hypertrophy. The primary outcome of interest is that rotational gradient (RG) is closely linked to global longitudinal strain (GLS).
Juan Geraldo   +10 more
wiley   +1 more source

When R‐Loops Go Awry: Genome Instability and Neurological Diseases

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 8, April 2026.
DNA normally exists as a double helix formed by two complementary strands. During gene transcription, however, one strand of DNA can bind to RNA, causing the other DNA strand to be displaced. This creates a structure called an R‐loop. R‐loops play important roles in normal cellular processes such as gene expression, DNA replication, and transcription ...
Nur Rasyiqin Rasli, Yu Katsuyama
wiley   +1 more source

Mavacamten for hypertrophic obstructive cardiomyopathy [PDF]

open access: yesThe Lancet, 2021
Eduard, Quintana   +2 more
openaire   +2 more sources

Models of the human heart for biomedical research: Opportunities and challenges

open access: yesPhysiological Reports, Volume 14, Issue 7, April 2026.
This manuscript reviews models that can be used to study the physiology and pathophysiology of the heart, and describes some the limitaions and ethical concerns associated with the use of human tissue. Abstract Model systems that mimic human cardiac structure and function are essential for the development of novel diagnostics and effective treatments ...
Katrin Streckfuss‐Bömeke   +21 more
wiley   +1 more source

Hypertrophic Obstructive Cardiomyopathy Present as Acute Myocardial Infarction in a Nonagenarian. [PDF]

open access: yesJACC Case Rep
Wan X   +8 more
europepmc   +1 more source

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