Results 21 to 30 of about 23,884 (245)

Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes

open access: yesNature Communications, 2021
Progress in precision medicine is limited by insufficient knowledge of transcriptomic or proteomic features in involved tissues that define pathobiological differences between patients.
Bradley A. Maron   +14 more
doaj   +1 more source

Neonatal hypertrophic cardiomyopathy with dyspnoea as the first symptom: a case report

open access: yesFrontiers in Pediatrics, 2023
Neonatal hypertrophic cardiomyopathy (HCM) is an idiopathic disease characterised by myocardial hypertrophy with normal or small ventricular chambers, a systolic hyperdynamic state and diastolic dysfunction.
Xiaoxia Li   +4 more
doaj   +1 more source

Mega Coronary Arteries with Obstructive Coronary Artery Disease in Hypertrophic Obstructive Cardiomyopathy: A Case Report and Literature Review

open access: yesJournal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2022
We report a rare case of hypertrophic obstructive cardiomyopathy (HOCM) presenting with mega coronary arteries with obstructive coronary artery disease.
Debasish Das   +3 more
doaj   +1 more source

Pattern and degree of left ventricular remodeling following a tailored surgical approach for hypertrophic obstructive cardiomyopathy. [PDF]

open access: yes, 2012
Background The role of a tailored surgical approach for hypertrophic cardiomyopathy (HCM) on regional ventricular remodelling remains unknown. The aims of this study were to evaluate the pattern, extent and functional impact of regional ventricular ...
Cecchi, F   +8 more
core   +2 more sources

Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy. [PDF]

open access: yes, 2014
Contraction in the mammalian heart is controlled by the intracellular Ca2+ concentration as it is in all striated muscle, but the heart has an additional signalling system that comes into play to increase heart rate and cardiac output during exercise or ...
Marston, SB, Messer, AE
core   +2 more sources

Surgical management of diastolic heart failure after septal myectomy for obstructive hypertrophic cardiomyopathyCentral MessagePerspective

open access: yesJTCVS Techniques, 2022
Objective: Some patients with obstructive hypertrophic cardiomyopathy may remain limited after surgical relief of the subaortic obstruction. In this report, we describe experience in surgical management of patients with advanced diastolic heart failure ...
Daokun Sun, MD, MPH   +5 more
doaj   +1 more source

An Unusual Case of Shock in an Octogenarian [PDF]

open access: yesAnnals of Geriatric Medicine and Research, 2021
An octogenarian presented to our hospital in shock after being “found down” at home. She was dehydrated, hypernatremic, and suffering from a urinary tract infection.
Michael A. Chen
doaj   +1 more source

Feline Hypertrophic Cardiomyopathy: A Spontaneous Large Animal Model of Human HCM. [PDF]

open access: yes, 2017
Hypertrophic cardiomyopathy (HCM) is a common disease in pet cats, affecting 10-15% of the pet cat population. The similarity to human HCM, the rapid progression of disease, and the defined and readily determined endpoints of feline HCM make it an ...
Freeman, Lisa M   +4 more
core   +2 more sources

Autosomal Dominant Polycystic Kidney Patients May Be Predisposed to Various Cardiomyopathies

open access: yesKidney International Reports, 2017
Mutations in PKD1 and PKD2 cause autosomal dominant polycystic kidney disease (ADPKD). Experimental evidence suggests an important role of the polycystins in cardiac development and myocardial function.
Fouad T. Chebib   +10 more
doaj   +1 more source

Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy

open access: yesClinics, 2013
OBJECTIVE: Obstructive sleep apnea is common among patients with hypertrophic cardiomyopathy and may contribute to poor cardiovascular outcomes. However, obstructive sleep apnea is largely unrecognized in this population.
Flávia B. Nerbass   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy