Results 1 to 10 of about 69 (64)

Collagen‐Based Hydrogels for Cartilage Regeneration

Orthopaedic Surgery, Volume 15, Issue 12, Page 3026-3045, December 2023., 2023
This review provided an overview of the progress made in research on collagen hydrogels with chondrocytes or stem cells, comprehensively covered the research progress and clinical applications of collagen‐based hydrogels that integrated inorganic or organic materials. Cartilage regeneration remains difficult due to a lack of blood vessels.
Lihui Sun, Yan Xu, Yu Han, Jing Cui, Zheng Jing, Dongbo Li, Jianguo Liu, Chunsheng Xiao, Dongsong Li, Bo Cai   +9 more
wiley   +1 more source

Biomechanical Impact of Phosphate Wasting on Articular Cartilage Using the Murine Hyp Model of X‐linked hypophosphatemia

JBMR Plus, Volume 7, Issue 10, October 2023., 2023
ABSTRACT Degenerative osteoarthritis (OA) is recognized as an early‐onset comorbidity of X‐linked hypophosphatemia (XLH), contributing to pain and stiffness and limiting range of motion and activities of daily living. Here, we extend prior findings describing biochemical and cellular changes of articular cartilage (AC) in the phosphate‐wasting ...
Carolyn M Macica, Steven M Tommasini
wiley   +1 more source

Complete form of pachydermoperiostosis with good initial response to etoricoxib: A case report

Clinical Case Reports, Volume 11, Issue 6, June 2023., 2023
X‐ray of hand showing cortical thickening and periosteal reaction in distal radius ulna and phalynges of hand of a patient with pachydermoperiostosis. Key Clinical Message Pachydermoperiostosis is a rare genetic disorder that closely resembles acromegaly. Diagnosis is usually based on distinct clinical and radiological features. Oral etoricoxib therapy
Abinash Baniya, Ayam Bhattarai, Bibek Devkota, Saurav Khatiwada, Pramod Kumar Kafle, Achyut Krishna Phuyal, Manoj Shahi   +6 more
wiley   +1 more source

Nosology of genetic skeletal disorders: 2023 revision

American Journal of Medical Genetics Part A, Volume 191, Issue 5, Page 1164-1209, May 2023., 2023
Abstract The “Nosology of genetic skeletal disorders” has undergone its 11th revision and now contains 771 entries associated with 552 genes reflecting advances in molecular delineation of new disorders thanks to advances in DNA sequencing technology.
Sheila Unger, Carlos R. Ferreira, Geert R. Mortier, Houda Ali, Débora R. Bertola, Alistair Calder, Daniel H. Cohn, Valerie Cormier‐Daire, Katta M. Girisha, Christine Hall, Deborah Krakow, Outi Makitie, Stefan Mundlos, Gen Nishimura, Stephen P. Robertson, Ravi Savarirayan, David Sillence, Marleen Simon, V. Reid Sutton, Matthew L. Warman, Andrea Superti‐Furga   +20 more
wiley   +1 more source

A case report of an extremely rare association of ankylosing spondylitis with pachydermoperiostosis

Clinical Case Reports, Volume 11, Issue 5, May 2023., 2023
Key Clinical Message We describe a case of a young man with features of pachydermoperiostosis and spondyloarthropathy. By describing this rarity, we aim to help build a database for future studies and construct a management plan that rheumatologists and clinicians can use.
Faiq I. Gorial, Nabaa Ihsan Awadh, Maryam A. Hamzah   +2 more
wiley   +1 more source

Hypertrophic osteoarthropathy associated with lung cancer: Possible links among hypoxia‐inducible factor‐1α, vascular endothelial growth factor, and hypervascularization

Thoracic Cancer, Volume 14, Issue 14, Page 1320-1324, May 2023., 2023
Lung cancer cells express vascular endothelial growth factor (VEGF), possibly releasing it into the circulation. The hypoxic tumor microenvironment may have caused some lung cancer cells to express hypoxia‐inducible factor‐1α (HIF‐1α), which contributes, at least in part, to VEGF production.
Ryuta Tagawa, Hiroshi Soda, Yosuke Dotsu, Hiroaki Senju, Satoshi Irifune, Masataka Yoshida, Shota Nakashima, Asuka Umemura, Keisuke Iwasaki, Hirokazu Taniguchi, Shinnosuke Takemoto, Yuichi Fukuda, Hiroshi Mukae   +12 more
wiley   +1 more source

Reprogramming of Mitochondrial Respiratory Chain Complex by Targeting SIRT3‐COX4I2 Axis Attenuates Osteoarthritis Progression

Advanced Science, Volume 10, Issue 10, April 5, 2023., 2023
The SIRT3‐medicated post‐translational acetylation of the mitochondrial respiratory chain has therapeutic potential for the treatment of osteoarthritis (OA). Mechanistically, SIRT3 directly binds and deacetylates COX4I2 to promote mitochondrial respiration activity.
Yijian Zhang, Yang Liu, Mingzhuang Hou, Xiaowei Xia, Junlin Liu, Yong Xu, Qin Shi, Zhongmin Zhang, Liang Wang, Yifan Shen, Huilin Yang, Fan He, Xuesong Zhu   +12 more
wiley   +1 more source

Paraneoplastic syndrome of arthropathies as presenting sign for non‐small cell lung cancer

Clinical Case Reports, Volume 11, Issue 4, April 2023., 2023
The aim of this study is to showcase an example of paraneoplastic syndrome, so other healthcare providers can be aware of early NSCLC manifestations. This is also important so providers do not dismiss review of symptoms that may not seem pertinent. Abstract The aim of this study is to showcase an example of paraneoplastic syndrome, so other healthcare ...
Alexander Kyle Lee, Gurpreet Singh, Cleveland W. Lewis Jr   +2 more
wiley   +1 more source

From mass to epidermolysis: a rare case of multiple metastatic solitary fibrous tumor with paraneoplastic pemphigus

, 2023
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 11, Page 1393-1395, November 2023.
Zijing Yang, Jingying Wang, Ruofei Shi, Qian Da, Xiaoqing Zhao, Jie Zheng, Meng Pan   +6 more
wiley   +1 more source

Hypertrophic osteoarthropathy in a sheep [PDF]

Ciência Rural, 2020
ABSTRACT: This research described the radiological, clinical and pathological aspects of hypertrophic osteoarthropathy in a seven-year-old Santa Inês ram. The main clinical features were lameness of the thoracic and pelvic limbs, rigid, cracking and enlarged of the humeroradial, humeroulnar and tibiofemoral joints, cervical spine stiffness, and severe ...
Hisadora Advincula da Silva Chaves Bom, Givaldo Bom da Silva Filho, Silvio Miguel Castillo Fonseca, Stephanie Carrelo de Lima, Huber Rizzo, Valdir Morais de Almeida, Francisco de Assis Leite Souza, Fábio de Souza Mendonça   +7 more
openaire   +4 more sources