Hypertrophic osteoarthropathy [PDF]
Archives of Medical Science, 2023 A 54-year-old man presented with cough and 3-month history of pain in bilateral knees and fingers. Physical examination revealed digital clubbing (Figure 1a and b) and tenderness in the knee joints.
Gang Wang +3 more
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Primary hypertrophic osteoarthropathy – a rare cause of pain and arthritis in children. Description of 5 cases [PDF]
Central European Journal of Immunology, 2022 Primary hypertrophic osteoarthropathy (PHOA) is a very rare disease. The typical triad of symptoms, i.e. digital clubbing, periosteal bone formation with bone and joint deformities and skin hypertrophy, may be accompanied by other specific conditions. In
Joanna Wójtowicz +3 more
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Etoricoxib as a treatment of choice for patients with SLCO2A1 mutation exhibiting autosomal recessive primary hypertrophic osteoarthropathy: A case report [PDF]
Frontiers in Genetics, 2022 We reported a 22-year-old Emirati male with autosomal recessive primary hypertrophic osteoarthropathy caused by a possibly pathogenic homozygous non-synonymous variant in the SLCO2A1 gene (NM_005630.3: c.289C>T, p.
Areej Albawa'neh +6 more
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Primary hypertrophic osteoarthropathy: genetics, clinical features and management [PDF]
Frontiers in Endocrinology, 2023 Primary hypertrophic osteoarthropathy (PHO) is a genetic disorder mainly characterized by clubbing fingers, pachydermia and periostosis. Mutations in the HPGD or SLCO2A1 gene lead to impaired prostaglandin E2 (PGE2) degradation, thus elevating PGE2 ...
Qi Lu +4 more
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Hypertrophic Osteoarthropathy: A Secondary Manifestation of Malignant Melanoma [PDF]
Case Reports in Rheumatology, 2021 Background. Hypertrophic osteoarthropathy (HOA) is a rare finding in the setting of metastatic melanoma. A majority of cases of secondary HOA involve lung malignancies.
Shiva Malaty, Aditya Gupta
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Coexistence of hypertrophic osteoarthropathy and myelofibrosis
Revista Brasileira de Reumatologia (English Edition), 2017 Hypertrophic osteoarthropathy (HOA) is a condition characterized by arthralgia/arthritis, clubbing, and periosteal reaction. Primary form of HOA is observed at early ages of life and is hereditary in nature. Secondary HOA is more frequently seen in clinical setting and occurs as a result of various disorders including inflammatory and malignant ...
Kelle, Bayram +5 more
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Nociceptive pain unmasking a serious pathology - paraneoplastic hypertrophic osteoarthropathy: A case report. [PDF]
Medicine (Baltimore), 2019 Rationale: Hypertrophic osteoarthropathy, also named Pierre Marie–Bamberger syndrome, represents a rare medical condition that may be considered either a primary or a secondary disease, and lung malignancies are responsible for more than two-thirds of ...
Ribigan AC +3 more
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Clinical and biochemical characteristics of 12 Chinese primary hypertrophic osteoarthropathy patients with HPGD mutations. [PDF]
Int J Biol Sci, 2022 Primary hypertrophic osteoarthropathy (PHO) is a rare genetic disease mainly affecting the skeletal and skin. Two genes involved in prostaglandin degradation are known to be responsible for PHO: HPGD and SLCO2A1.
Lu Q +5 more
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Primary hypertrophic osteoarthropathy and bilateral transient lateral patellar dislocation in an adolescent. [PDF]
BJR Case Rep, 2022 This case report is of the index case of bilateral transient patellar dislocation in a patient with primary hypertrophic osteoarthropathy. Primary hypertrophic osteoarthropathy is a rare complex disorder with variable presentation and thus frequently ...
Jeyabaladevan S +3 more
europepmc +2 more sources
Pachydermoperiostosis Mimicking Inflammatory Arthritis: Case Description and Narrative Review [PDF]
Rheumato, 2023 Pachydermoperiostosis (PDP), also called primary hypertrophic osteoarthropathy (HOA), is a rare genetic disease with typical thickening of the skin (pachydermia) and rheumatic manifestations, with clubbing of the fingers and toes and periostosis of the ...
AKM Kamruzzaman +7 more
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