Primary hypertrophic osteoarthropathy: genetics, clinical features and management [PDF]
Frontiers in Endocrinology, 2023 Primary hypertrophic osteoarthropathy (PHO) is a genetic disorder mainly characterized by clubbing fingers, pachydermia and periostosis. Mutations in the HPGD or SLCO2A1 gene lead to impaired prostaglandin E2 (PGE2) degradation, thus elevating PGE2 ...
Qi Lu +4 more
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Primary Hypertrophic Osteoarthropathy: A case series [PDF]
Journal of Marine Medical SocietySkeletal dysplasia encompasses a spectrum of over 400 rare inheritable skeletal abnormalities typically manifested early in childhood. Hypertrophic Osteoarthropathy is a clinical syndrome marked by abnormal skin and osseous tissue proliferation at the ...
BANSAL, PURNA +4 more
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Hypertrophic Osteoarthropathy: A Secondary Manifestation of Malignant Melanoma [PDF]
Case Reports in Rheumatology, 2021 Background. Hypertrophic osteoarthropathy (HOA) is a rare finding in the setting of metastatic melanoma. A majority of cases of secondary HOA involve lung malignancies.
Shiva Malaty, Aditya Gupta
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Early Imaging Findings of Hypertrophic Osteoarthropathy Mimicking Bone Metastasis from Extrathoracic Malignancy [PDF]
대한영상의학회지, 2021 Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by digital clubbing, periosteal bone formation, and synovial effusions. Secondary HOA is associated with intrathoracic malignancy in most cases; however, in rare cases, HOA can be caused ...
Ji Yeon Hwang +3 more
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SLCO2A1 gene is the causal gene for both primary hypertrophic osteoarthropathy and hereditary chronic enteropathy. [PDF]
J Orthop Translat, 2021 Umeno J +4 more
europepmc +3 more sources
Hypertrophic osteoarthropathy in a sheep [PDF]
Ciência Rural, 2020 : This research described the radiological, clinical and pathological aspects of hypertrophic osteoarthropathy in a seven-year-old Santa Inês ram. The main clinical features were lameness of the thoracic and pelvic limbs, rigid, cracking and enlarged of ...
Hisadora Advincula da Silva Chaves Bom +7 more
doaj +2 more sources
Pachydermoperiostosis Mimicking Inflammatory Arthritis: Case Description and Narrative Review [PDF]
Rheumato, 2023 Pachydermoperiostosis (PDP), also called primary hypertrophic osteoarthropathy (HOA), is a rare genetic disease with typical thickening of the skin (pachydermia) and rheumatic manifestations, with clubbing of the fingers and toes and periostosis of the ...
AKM Kamruzzaman +7 more
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Recurrent hypertrophic pulmonary osteoarthropathy in an adult with bronchiectasis [PDF]
Respirology Case Reports, 2020 Hypertrophic pulmonary osteoarthropathy (HPOA) is a well‐documented complication of pulmonary malignancy and cystic fibrosis (CF). However, HPOA associated with exacerbations of non‐CF bronchiectasis has only been reported once previously in an ...
Amelia Tekiteki +4 more
doaj +2 more sources
Hypertrophic Osteoarthropathy Associated with Probable Smear-Negative Pulmonary Tuberculosis [PDF]
Case Reports in Rheumatology, 2022 Association of hypertrophic osteoarthropathy (HOA) with pulmonary tuberculosis is rarely reported, especially with smear-negative pulmonary tuberculosis (SNPT), in which its diagnosis is a challenge.
Mohamed Ahmed Ghassem +5 more
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