A Diagnostic Cascade Triggered by Physical Examination: Uncovering Asymptomatic Left Ventricular Dysfunction and Critical Carotid Disease in a Hypertensive Patient. [PDF]
Lyu X.
europepmc +1 more source
Comparative Genomics and Functional Evidence for Convergent Adaptation to Hypoxia in Mammals
This study reveals convergent selection in mammals adapted to hypoxia. Functional assays demonstrate that amino acid mutations reduce oxidative stress, attenuate hypoxia‐induced injury, and modulate the hypoxia‐inducible transcription factor (HIF)‐driven hypoxic response.
Hao Dong +5 more
wiley +1 more source
Apical Hypertrophic Cardiomyopathy (Yamaguchi Syndrome) Presenting as Acute Coronary Syndrome Mimic: A Case Report. [PDF]
Shirbhate L.
europepmc +1 more source
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source
Left ventricular hypertrophy: diagnostics pitfalls
Swiss Medical Weekly
doaj +1 more source
Extreme Left Ventricular Hypertrophy in Pediatric Hypertrophic Obstructive Cardiomyopathy. [PDF]
Smajlović E, Bolic Alic A.
europepmc +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
The ECG in Congenital Heart Disease: What Is Beyond the Tracing? [PDF]
Ezzeddine FM, Asirvatham SJ.
europepmc +1 more source
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer +5 more
wiley +1 more source

