Results 141 to 150 of about 2,143,617 (291)

Sustained seizure freedom with fenfluramine for refractory epilepsy due to 7q32‐q34 deletion syndrome

open access: yes
Epileptic Disorders, EarlyView.
Divya Veerapaneni   +2 more
wiley   +1 more source

Old disease, new twist

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari   +4 more
wiley   +1 more source

Periodontitis and its association with left ventricular geometry and function: A cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study investigated the cross‐sectional association between periodontal status and left ventricular (LV) geometry and function, an early and prognostically relevant marker of cardiovascular disease. Methods Data were drawn from two population‐based cohorts in the Study of Health in Pomerania (SHIP): SHIP‐START‐2 (N = 2333) and ...
Maja Trost   +8 more
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers   +5 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Unmasking AL Cardiac Amyloidosis During Familial Cardiomyopathy Screening. [PDF]

open access: yesJACC Case Rep
Barberis Barcia G   +9 more
europepmc   +1 more source

The Impact of Water Exchange on Estimates of Myocardial Blood Flow and Extracellular Volume Fraction Using Dynamic Contrast‐Enhanced MRI in Patients Treated for Severe Aortic Stenosis

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To investigate the impact of intra/extracellular water exchange (WX) on quantitative dynamic contrast‐enhanced (DCE) MRI in patients with severe aortic stenosis (AS). The aims were to compare low‐dose (WX insensitive) and high‐dose (WX sensitive) DCE‐MRI measurements, and to compare data acquired before and after aortic valve ...
Alex Makins   +5 more
wiley   +1 more source

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