Results 171 to 180 of about 2,143,617 (291)

Comparative Genomics and Functional Evidence for Convergent Adaptation to Hypoxia in Mammals

Integrative Zoology, EarlyView.
This study reveals convergent selection in mammals adapted to hypoxia. Functional assays demonstrate that amino acid mutations reduce oxidative stress, attenuate hypoxia‐induced injury, and modulate the hypoxia‐inducible transcription factor (HIF)‐driven hypoxic response.
Hao Dong, Chunxu Wang, Enqing Pei, Liang Zhao, Simin Chai, Ran Tian   +5 more
wiley   +1 more source

Case Report: Hereditary ATTR-CA presenting with recurrent severe abdominal cramps: a diagnostic challenge. [PDF]

Front Cardiovasc Med
Mo C, Liao K, Li Y, Luo S, Huang B.
europepmc   +1 more source

What anabolic–androgenic steroids reveal about the limits of current harm reduction models

Addiction, EarlyView.
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski, Jason M. Nagata, Suzanne Nielsen   +2 more
wiley   +1 more source

Large left ventricular apical aneurysm in a child with Noonan syndrome and hypertrophic cardiomyopathy. [PDF]

Ann Pediatr Cardiol
Mohanachandran A, Thejaswi P, Sivakumar K, Agarwal R.   +3 more
europepmc   +1 more source

Multiple cardiac malformations in a calf

Australian Veterinary Journal, EarlyView.
This paper describes the morphopathological aspects of a case of multiple cardiac malformations in a calf. A two‐day‐old male calf of undefined breed was born with an ectopic heart, presenting with dyspnoea and in lateral recumbency. The owner had repositioned the exposed heart beneath the adjacent skin, which was suclosed, without additional incisions
LA Soares, IC Matias, DRS Garcia, HS Oliveira Filho, SM Figueiredo, GX Medeiros, LÂ Maia, GJN de Galiza   +7 more
wiley   +1 more source

Association between controlling nutritional status score and left ventricular hypertrophy in adults: A single-center retrospective cross-sectional study. [PDF]

Medicine (Baltimore)
Yang GY, Tang J, Yang L, Li YH.
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Coexistence of Hypertrophic Cardiomyopathy and Hereditary Transthyretin Amyloid Cardiomyopathy. [PDF]

JACC Case Rep
Coderre R, Tersalvi G, Adigun RO, Boilson BA, Borgeson DD, Clavell AL, Chang IC, Dispenzieri A, Grogan M, AbouEzzeddine OF.   +9 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Left ventricular hypertrophy: diagnostics pitfalls

Swiss Medical Weekly, 2004
Swiss Medical Weekly
doaj   +1 more source