Results 211 to 220 of about 528,761 (298)

SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy

Circulation, 2017
Xiaoqiang Tang, Xiao-Feng Chen, Nan-Yu Wang, Xiao-Man Wang, Shu-ting Liang, Wei Zheng, Yun-biao Lu, Xiang Zhao, D. Hao, Zhu-qin Zhang, M. Zou, De-Pei Liu, Houzao Chen   +12 more
semanticscholar   +1 more source

Valorization of the peel and husk of guaraná (Paullinia cupana): oil extraction, chemical composition, cytotoxicity, and antitumor potential

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Guaraná (Paullinia cupana) is a fruit native to the Amazon region. Due to its widespread use, primarily in beverages, its production has grown over the years. The seed is the only commercially valuable part of the fruit so the guaraná production chain generates byproducts, including peel, husk, and spent seed.
Leiliane do Socorro Sodré de Souza, Guilherme Teixeira de Azevedo, Eduardo Leonarski, Giovana Lima de Souza, Rafael Lopes e Oliveira, Sérgio Duvoisin Junior, Karina Cesca, Débora de Oliveira, Anderson Mathias Pereira, Ariane Mendonça Kluczkovski   +9 more
wiley   +1 more source

USP13-Mediated selective autophagy of eIF5B promotes pathological cardiac hypertrophy. [PDF]

Cell Mol Life Sci
Ye Y, Xu J, Jin C, Li X, Wu X, Zhou C, Gao L, Zhong Z, Li X, Chen S, Wei Y, Peng S, Liu S.   +12 more
europepmc   +1 more source

FHL1 complexes with NFATc1 and GATA2 promoting skeletal muscle hypertrophy during growth but not aging

, 2017
Kane Jordan Michael
openalex   +1 more source

A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

Proceedings of the National Academy of Sciences of the United States of America, 2006
E. van Rooij, L. Sutherland, Ning Liu, Andrew H. Williams, John R. McAnally, R. Gerard, J. Richardson, E. Olson   +7 more
semanticscholar   +1 more source

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee, Hyun Chul Kim, Young Ran Yoon, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu   +5 more
wiley   +1 more source

Mechanism of RNA Oxidation and Its Inhibitor Involved in Ang II-Induced Cardiomyocyte Hypertrophy. [PDF]

Aging Med (Milton)
Liu T, Bian J.
europepmc   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Electrocardiographic markers of hypertrophy in children: revisiting R/S overlap and the Katz-Wachtel phenomenon. [PDF]

Front Pediatr
Owsianka N, Schober L, Sallmon H, Scherr D, Köstenberger N, Manninger M, Öffl N, Kurath-Koller S.   +7 more
europepmc   +1 more source