Results 81 to 90 of about 749,882 (394)

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Prognostic value of left ventricular mass index in patients with mild and moderate aortic stenosis

open access: yesКардиоваскулярная терапия и профилактика, 2019
Aim. To study the prognostic value of Left Ventricular Mass (LVM) with asymptomatic aortic stenosis (AS) in a long-term outpatient study, as well as the effect of the LVM on major cardiovascular events (CVe).Material and methods.
A. S. Ryazanov   +3 more
doaj   +1 more source

Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification

open access: yesAdipocyte, 2020
The distinction between biological processes of adipose tissue expansion is crucial to understanding metabolic derangements, but a robust method for quantifying adipocyte size has yet to be standardized.
Anne S Maguire   +5 more
doaj   +1 more source

Clinical significance of the buccal fat pad: how to determine the correct surgical indications based on preoperative analysis [PDF]

open access: yes, 2018
Background: Despite the multitude of clinical and aesthetic uses, the correct surgical indications for buccal fat pad (BFP) removal have yet to be fully elucidated.
Bencardino, Davide   +6 more
core   +1 more source

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

open access: yesAdvanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo   +13 more
wiley   +1 more source

Research Note: Muscle hypertrophy is associated with reversed sexual dimorphism in body size of quail

open access: yesPoultry Science
: Sexual dimorphism is phenotypic differences between males and females in the same species. In general, males in most animals are larger than females at the same age, however, in quail, females have a larger body size with greater muscle mass than males.
Dong-Hwan Kim   +3 more
doaj   +1 more source

Expression of Estrogen Receptor Alpha and Evaluation of Histological Degeneration Scores in Fibroblasts of Hypertrophied Ligamentum Flavum: A Qualitative Study

open access: yesBiomolecules, 2021
The most common spinal disorder in elderly is lumbar spinal stenosis (LSS), resulting partly from ligamentum flavum (LF) hypertrophy. Its pathophysiology is not completely understood.
Christina C. Westhoff   +6 more
doaj   +1 more source

Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training [PDF]

open access: yes, 2008
Purpose of Review: Sarcopenia (skeletal muscle wasting with aging) is thought to underlie a number of serious age-related health issues. While it may be seen as inevitable, decreasing this gradual loss of muscle is vital for healthy aging.
Cribb, Paul J, Hayes, Alan
core   +1 more source

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

open access: yesNature Communications, 2018
Pressure overload induces a transition from cardiac hypertrophy to heart failure, but its underlying mechanisms remain elusive. Here we reconstruct a trajectory of cardiomyocyte remodeling and clarify distinct cardiomyocyte gene programs encoding ...
S. Nomura   +19 more
semanticscholar   +1 more source

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