Results 101 to 110 of about 13,666 (254)

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng   +3 more
wiley   +1 more source

Effects of Agomelatine on Sleep Across Populations: A Systematic Review and Meta‐Analysis

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Agomelatine, a melatoninergic antidepressant, is often prescribed to improve sleep disturbance, though meta‐analytic evidence is currently lacking. This systematic review and meta‐analysis assessed its efficacy and tolerability in sleep outcomes compared to placebo.
Anastasios Stefanou   +7 more
wiley   +1 more source

Excessive Daytime Sleepiness, but Not Insomnia Is Associated With Dyslipidaemia in Patients With Obstructive Sleep Apnoea Participating in ESADA

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Excessive daytime sleepiness (EDS) as well as insomnia have been associated with a higher risk for cardiovascular disease in patients with obstructive sleep apnoea (OSA). The link is not fully understood but may involve dyslipidaemia. The aim of the study was to analyse if the EDS and insomnia phenotypes were associated with deranged serum ...
Andras Bikov   +61 more
wiley   +1 more source

Rest Assured: The Association of Structural, Functional Support, and Loneliness With Subjective Sleep Health

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep is increasingly understood as a socially embedded phenomenon. This study examined how structural and functional aspects of social support, as well as loneliness, relate to sleep health in a German sample of middle‐aged adults (N = 5388).
Eva De Camargo   +9 more
wiley   +1 more source

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman   +11 more
wiley   +1 more source

An Electroencephalographic Study of Sleep Spindle and Infraslow Oscillation in Children With Autism Spectrum Disorder

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT We investigated whether sleep microstructures show spatial differences in young children with autism compared with typically developing peers. 32‐channel electroencephalography (EEG) during natural sleep after 5–6 h of partial sleep deprivation was recorded from 53 children (26 with autism, 27 typically developing; 1.1–5.1 years).
Kevin Liu   +7 more
wiley   +1 more source

Sleep‐Related Attentional Bias in Insomnia: A Drift Diffusion Model Approach

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Cognitive models propose that insomnia is maintained in part by selective attention to sleep‐related information, yet reaction‐time indices alone offer limited mechanistic specificity. We investigated sleep‐related attentional bias in adolescents and young adults with insomnia disorder (n = 201; aged 15–24 years; DSM‐5) using a sleep‐related ...
Isla Tsz Kwan Hui   +12 more
wiley   +1 more source

Phenotypic Variability in Slow‐Wave Sleep in Depression: Associations With Clinical Profiles and Disorder Severity

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Slow‐wave sleep (SWS; stage N3) is often reported as reduced in depression, yet variability across depressive phenotypes remains poorly characterised. This study aimed to determine whether N3 architecture—proportion, duration, and latency—identifies clinically distinct profiles in major depressive episode (MDE).
Antoine Salmeron   +8 more
wiley   +1 more source

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