Results 141 to 150 of about 122,902 (344)

Opioid‐free vs. opioid‐inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta‐analysis of randomised controlled trials

open access: yesAnaesthesia, EarlyView.
Summary Introduction Concerns about opioid‐related adverse effects have increased interest in opioid‐free anaesthesia, but the benefits compared with opioid‐inclusive techniques, especially in the presence of regional anaesthesia, remain uncertain. Methods We undertook a systematic review with a network meta‐analysis of randomised controlled trials ...
Clístenes C. de Carvalho   +11 more
wiley   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro   +14 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Trends in the multiple prescriptions of hypnotic drugs in a university outpatient in Japan

open access: yesNeuropsychopharmacology Reports
Aims In Japan, the daily dosage of hypnotic drugs for insomnia treatment is increasing year by year, and over‐dependence on treatment with hypnotic drugs is a major problem.
Takao Kato   +9 more
doaj   +1 more source

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki   +4 more
wiley   +1 more source

What Linked Data Can Tell Us About the Increasing Numbers of Children Entering Public Care

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT The number of children in public care in Wales, UK, rose from the mid‐1990s to 2021. It is unclear if this change was related to increases in risk factors in parents, changes in the impact of risk factors, or changing policies and practices.
Nell Warner   +4 more
wiley   +1 more source

HYPNOSIS FOR IMPROVEMENT OF PHYSICAL STRENGTH AND RESISTANCE

open access: yesPublicaciones, 2014
In this case study we assessed the effectiveness of hypnosis for the physical force in sportsmen. Participant was 1 amateur cyclist with hypnotic suggestion.
Félix Zurita Ortega   +3 more
doaj  

Quebec hypnotherapists' social representations of hypnosis and power [PDF]

open access: yes, 2019
Hypnosis appears as a practice that features practitioners who deliberately display their power and the power of their technique. During a therapeutic interaction, the actors involved will mobilize representations and knowledge related to their ...
Lavoie, Claude
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