Results 11 to 20 of about 1,172 (111)

Effect-site concentration of remimazolam at loss and recovery of responsiveness during general anesthesia: a simulation study [PDF]

open access: yesAnesthesia and Pain Medicine, 2022
Background The objective of this study was to investigate the effect-site concentration (Ce) of remimazolam at loss of response (LOR) and recovery of response (ROR) in patients underwent general anesthesia using simulation. In addition, the relationships
Kyung Mi Kim   +5 more
doaj   +1 more source

Use of anxiolytics and hypnotic drugs during COVID-19 pandemic: The literature review [PDF]

open access: yesMedicinski Podmladak, 2022
Anxiolytics and hypnotics are widely used drugs. First-line psychiatric indications for benzodiazepines (BZD) are alcohol/sedative-hypnotic withdrawal and catatonia, while panic disorder, general anxiety disorder, social anxiety disorder and insomnia are
Trajkovski Tea, Marić Nađa P.
doaj   +1 more source

Remimazolam: pharmacological characteristics and clinical applications in anesthesiology [PDF]

open access: yesAnesthesia and Pain Medicine, 2022
A novel ultra-short-acting benzodiazepine (BDZ), remimazolam (CNS 7056), has been designed by ‘soft drug’ development to achieve a better sedative profile than that of the current drugs.
Kyung Mi Kim
doaj   +1 more source

Novel 2-substituted-5-(4-chloro-2-phenoxy)phenyl-1,3,4-oxadiazole derivatives, ligands of GABAA/benzodiazepine receptor complex

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Agonists of Benzodiazepine (BZD) receptor are exhaustively used in the control of muscle spasms, seizure, anxiety, and insomnia. BZDs have some unwanted effects; therefore, the development of new BZD receptor agonists with better efficacy and fewer ...
Elham Rezaee   +7 more
doaj   +1 more source

Neuropharmacological Activity of the Acetonic Extract of Malpighia mexicana A. Juss. and Its Phytochemical Profile

open access: yesScientia Pharmaceutica, 2023
Mental and neurological disorders are conditions that affect thoughts, emotions, behavior, and relationships. Malpighia mexicana A. Juss. is a plant used in Mexican traditional medicine for the treatment of such disorders.
Dante Avilés-Montes   +11 more
doaj   +1 more source

The difference in mean arterial pressure induced by remimazolam compared to etomidate in the presence of fentanyl at tracheal intubation: A randomized controlled trial

open access: yesFrontiers in Pharmacology, 2023
Background: Combined use of hypnotic and opioids during anesthesia inductions decreases blood pressure. Post-induction hypotension (PIHO) is the most common side effect of anesthesia induction. We aimed to compare the difference in mean arterial pressure
Xiaofang Huang   +9 more
doaj   +1 more source

Management of Hypnotics in Patients with Insomnia and Heart Failure during Hospitalization: A Systematic Review

open access: yesNursing Reports, 2021
Background: Heart failure is a chronic, progressive syndrome of signs and symptoms, which has been associated to a range of comorbidities including insomnia. Acute decompensation of heart failure frequently leads to hospital admission.
Pablo Jorge-Samitier   +4 more
doaj   +1 more source

Effect of Thai traditional antinausea remedy on hypnotic and sedative activity in animal experimental models: Interaction with drugs acting at GABAA receptor

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2019
Thai traditional antinausea remedy is drug registered in the National List of Essential Medicines for the treatment of blood circulation disorders, dizziness, fatigue, and insomnia.
Watchara Damjuti   +2 more
doaj   +1 more source

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