Results 281 to 290 of about 122,902 (344)

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 172-185, January 2026.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, Manjunath S. Shet, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

A clinical study of methaqualone: a new nonbarbiturate hypnotic.

, 1961
R Barcelo
openalex   +1 more source

L‐Quebrachitol Enhances Sedative Effect of Diazepam Through GABAergic Pathway: Animal and Computational Studies

Brain and Behavior, Volume 16, Issue 1, January 2026.
L‐quebrachitol (LQL) significantly enhanced the sedative effects of diazepam in thiopental sodium‐induced chicks by reducing sleep latency and prolonging duration. Molecular docking revealed LQL's interaction with GABAA receptor (α1 and β2 subunits), supporting a GABAergic mechanism and highlighting its potential as a safe, natural sedative agent ...
Asifa Asrafi, Mohammad Aslam, Md. Sakib Al Hasan, Mohammed Burhan Uddin, Emon Mia, Mohammad Y. Alshahrani, Sumaya Akter Bithi, Mst. Sumaia Akter, Md. Arif Hossain, Md. Torequl Islam   +9 more
wiley   +1 more source

Understanding Autism through the Eyes of Nurses: a Cross‐Sectional Study

Brain and Behavior, Volume 16, Issue 1, January 2026.
ABSTRACT Purpose: Nurses are key to the early detection of autism spectrum disorder (ASD). However, gaps in the literature and misconceptions can delay care; evidence of this from Saudi Arabia is limited. This study was done to examine nurses’ understanding of autism within the Saudi context, inform targeted educational programs, enhance clinical ...
Monirah Albloushi, Reem Saeed Alghamdi, Mona Alqahtani   +2 more
wiley   +1 more source

Effect of Lemborexant-Based Sleep Medication Formulary on Benzodiazepine Reduction and Clinical Outcomes: A Single-Center Retrospective Study. [PDF]

Neuropsychopharmacol Rep
Aoki S, Takada K, Sugama T, Kimiwada M, Hoshino T, Koike K, Akada H, Saiga T, Sato S, Shinkai R, Shibata Y, Tomita T.   +11 more
europepmc   +1 more source

From Molecule to Meaning: Click and Bioorthogonal Chemical Reporters for Plant Systems, Biological Imaging, and Artistic Expression

ChemBioChem, Volume 27, Issue 1, January 2026.
At the intersection of chemical biology, plant imaging, and contemporary art, this review introduces the concept of chembioart. By tracing how chemical reporters illuminate plant biomolecules in vivo, their role not only in advancing scientific understanding but also in inspiring transdisciplinary collaborations and visual expression is highlighted ...
Marie Hinnebo, Clémence Simon, Adèle Tilouine, Corentin Spriet, Christophe Biot   +4 more
wiley   +1 more source

Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness. [PDF]

Commun Biol
Fotiadis P, McKinstry-Wu AR, Weinstein SM, Cook PA, Elliott M, Cieslak M, Duda JT, Satterthwaite TD, Shinohara RT, Proekt A, Kelz MB, Detre JA, Bassett DS.   +12 more
europepmc   +1 more source

Will the Hypnotized Person Commit a Crime? Modern Research on an Old Question [PDF]

, 1966
Murray, John R.
core   +1 more source

Pitolisant Inhibits Alcohol Drinking and Improves Withdrawal Negative Affect Through Lateral Habenula Histaminergic Signaling in Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pitolisant, an FDA‐approved H3R antagonist, counteracts the rewarding and sedative effects of ethanol, reduces alcohol intake, and alleviates the negative affect during withdrawal. This might occur via the antagonism of presynaptic autoreceptors and heteroreceptors H3Rs in the lateral habenula, thereby activating the H2R/p‐CREB/BDNF signaling and ...
Yan Zhao, Yixin Fu, Tianhao Liu, Zanhao Yang, Zhengzhong Yang, Bingqing Chen, Lipeng Zhou, Juntao Yang, Duo Chen, Xiaojiao Han, Ying Tang, Jiang‐Hong Ye, Chao‐Yu Miao, Rao Fu   +13 more
wiley   +1 more source

Clinical behavior toward outpatients with major depressive disorder based on guideline education for psychiatrists. [PDF]

PCN Rep
Yamagata H, Ide K, Ochi S, Iga JI, Fukumoto K, Ichihashi K, Katsumoto E, Takeshima M, Imai K, Shimamura Y, Matsumoto J, Hasegawa N, Kawamata Y, Tsuboi T, Numata S, Ohi K, Watanabe K, Yamada H, Hori H, Hashimoto R, Yasui-Furukori N.   +20 more
europepmc   +1 more source