Results 51 to 60 of about 122,902 (344)

Hypnotic Activity of Carthamus tinctorius Petal Extracts and Its Purified Components [PDF]

Research Journal of Pharmacognosy
Background and objectives: Sleep disorders are common in industrialized and developing societies. This study aimed to investigate the sleep-inducing potential of Carthamus tinctorius L.
Abdorahim Nouri, Mahdi Vazirian, Hamid Reza Monsef Esfahani, Mohammad Sharifzadeh, Reza Jahani, Mehran Mirabzadeh Ardakani, Mahnaz Khanavi, Mohammad Reza Shams Ardekani*   +7 more
doaj   +1 more source

Balance dysfunction the most significant cause of in-hospital falls in patients taking hypnotic drugs: A retrospective study.

PLoS ONE, 2022
PurposePreventing falls in patients is one of the most important concerns in acute hospitals. Balance disorder and hypnotic drugs lead to falls. The Standing Test for Imbalance and Disequilibrium (SIDE) is developed for the evaluation of static standing ...
Ryuki Hashida, Hiroo Matsuse, Shinji Yokoyama, Sayuri Kawano, Eriko Higashi, Hiroshi Tajma, Masafumi Bekki, Sohei Iwanaga, Koji Hara, Yosuke Nakamura, Yuji Kaneyuki, Takeshi Nago, Yoshihiro Fukumoto, Motohiro Ozone, Naohisa Uchimura, Naoto Shiba   +15 more
doaj   +1 more source

Multimorbidity and use of hypnotic and anxiolytic drugs: cross-sectional and follow-up study in primary healthcare in Iceland

BMC Family Practice, 2016
BackgroundThe prevalence of multimorbidity is increasing worldwide, presumably leading to an increased use of medicines. During the last decades the use of hypnotic and anxiolytic benzodiazepine derivatives and related drugs has increased dramatically ...
K. Linnet, L. Gudmundsson, Frida G. Birgisdottir, E. Sigurdsson, M. Jóhannsson, M. O. Tomasdottir, J. Sigurdsson   +6 more
semanticscholar   +1 more source

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

British Journal of Clinical Pharmacology, EarlyView.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro, Clémence Lacroix, Élisabeth Jouve, Élisabeth Frauger, Maryse Lapeyre‐Mestre, Joëlle Micallef   +5 more
wiley   +1 more source

Advances in the Treatment of Chronic Insomnia: A Narrative Review of New Nonpharmacologic and Pharmacologic Therapies

Neuropsychiatric Disease and Treatment, 2021
Russell Rosenberg,1 Leslie Citrome,2 Christopher L Drake3 1Neurotrials Research, Atlanta, GA, USA; 2Department of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, NY, USA; 3Thomas Roth Sleep Disorders and Research Center, Henry ...
Rosenberg R, Citrome L, Drake CL
doaj  

The persistence of chronic opioid use in patients with inflammatory bowel disease—A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård, Caroline Theilgaard Thorarinsson, Jan Nielsen, Mette Louise Andersen, Jens Kjeldsen, Torben Knudsen, Rahul S. Dalal   +6 more
wiley   +1 more source

The Association between Sleep Problems, Sleep Medication Use, and Falls in Community-Dwelling Older Adults: Results from the Health and Retirement Study 2010 [PDF]

, 2016
Background. Very few studies have assessed the impact of poor sleep and sleep medication use on the risk of falls among community-dwelling older adults. The objective of this study was to evaluate the association between sleep problems, sleep medication ...
Min, Yaena, Nadpara, Pramit A., Slattum, Patricia W.   +2 more
core   +3 more sources

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

British Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia, Huang Xingxing, Jin Lu, Wang Ruwei   +3 more
wiley   +1 more source

Trends, correlates, and disease patterns of sedative-hypnotic use among elderly persons in Taiwan

BMC Psychiatry, 2022
Objective The population-based National Health Insurance database was adopted to investigate the prevalence, correlates, and disease patterns of sedative-hypnotic use in elderly persons in Taiwan.
Chia-Lun Kuo, I-Chia Chien, Ching-Heng Lin   +2 more
doaj   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source