Results 61 to 70 of about 92,839 (346)

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Multidisciplinary Approach to Deprescribing Sedative-Hypnotic Medications in Geriatric Primary Care

Journal of Primary Care & Community Health, 2022
Introduction/Objectives: Due to the risks associated with sedative hypnotic medications in older adults, our study evaluated the impact of a multidisciplinary approach to deprescribing in geriatric primary care clinics.
Danielle R. Fixen, Samantha A. Farro, Prajakta Shanbhag, Bennett L. Parnes, Maria V. Vejar   +4 more
doaj   +1 more source

Insomnia Diagnosis, Prescribed Hypnotic Medication Use, and Risk for Serious Fall Injuries in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study [PDF]

, 2022
S. Justin Thomas, Swati Sakhuja, Lisandro D. Colantonio, Mei Li, Paul Muntner, Kristi Reynolds, C. Barrett Bowling   +6 more
openalex   +1 more source

Management of paediatric procedure-related cancer pain

, 1999
Paediatric malignancy is not always painful in its own right; however, young patients with cancer undergo numerous painful procedures for diagnosis, therapy and supportive care, including lumbar puncture, bone marrow aspiration and biopsy.
Liossi, C.
core   +1 more source

From Molecule to Meaning: Click and Bioorthogonal Chemical Reporters for Plant Systems, Biological Imaging, and Artistic Expression

ChemBioChem, EarlyView.
At the intersection of chemical biology, plant imaging, and contemporary art, this review introduces the concept of chembioart. By tracing how chemical reporters illuminate plant biomolecules in vivo, their role not only in advancing scientific understanding but also in inspiring transdisciplinary collaborations and visual expression is highlighted ...
Marie Hinnebo, Clémence Simon, Adèle Tilouine, Corentin Spriet, Christophe Biot   +4 more
wiley   +1 more source

Marine Polyphenol Phlorotannins as a Natural Sleep Aid for Treatment of Insomnia: A Review of Sedative–Hypnotic Effects and Mechanism of Action

Marine Drugs, 2022
Insomnia is a common sleep disorder. Natural sleep aids are gaining worldwide popularity as alternatives to prescription drugs for improving sleep.
Seonghui Kim, Duhyeon Kim, Min Young Um, Minseok Yoon, Jae-Suk Choi, Yung Hyun Choi, Suengmok Cho   +6 more
doaj   +1 more source

Skeletal Editing from Pyridine to Aniline via C‐Insertion and N‐Isomerization

ChemistryEurope, EarlyView.
A concise protocol is presented that converts pyridines into anilines by externalizing the original pyridine nitrogen at either the "ipso" or "ortho" position, which results in para or meta‐primary aniline products. A key carbene‐insertion step precedes nitrogen migration, preserving both ring size and overall structure.
Yun Luo, Jing Dai, Yongchang Wei, Chang Min   +3 more
wiley   +1 more source

Leptocarpus disjunctus prolongs sleeping time and increases nonrapid eye movement sleep with additional anxiolytic capacity

Journal of Advanced Pharmaceutical Technology & Research, 2017
Leptocarpus disjunctus Mast. (Restionaceae) is an edible plant which has indigenous warnings regarding its side effects which can manifest as dizziness. This study investigated hypnotic and anxiolytic properties using several animal models.
Watchara Damjuti, Thanes Fuangfoo, Chanida Palanuvej, Tingli Li, Nijsiri Ruangrungsi   +4 more
doaj   +1 more source

The Mass Psychology of Classroom Discourse [PDF]

, 2017
In a majority of cases observed in classrooms over the last several decades, what has gone by the name “discussion” is not discussion, but rather an interaction better known as recitation.
David Backer
core   +1 more source

A prospective randomized crossover trial investigating melatonin versus sleep deprivation for sleep induction in nap electroencephalography

Epilepsia Open, EarlyView.
Abstract Objective Electroencephalography (EEG) plays a fundamental role in the diagnosis and classification of epilepsy, and inducing sleep during EEG can improve patient cooperation and enhance the detection of epileptiform activity. Despite its importance, there is currently no standardized approach for sleep induction in pediatric EEG recordings ...
Valentina De Giorgis, Costanza Varesio, Massimiliano Celario, Carlo Alberto Quaranta, Francesca Ferraro, Ludovica Pasca, Guido Fedele, Grazia Papalia, Michela Palmisani, Cinzia Fattore, Paola Rota, Valentina Franco   +11 more
wiley   +1 more source