Results 201 to 210 of about 27,102 (328)

Reflections on Consciousness in Intensive Care

Acta Paediatrica, Volume 115, Issue 2, Page 275-284, February 2026.
ABSTRACT Evaluating consciousness in intensive care is pivotal to relieving suffering with analgesic or sedative drugs and in prognosis and diagnoses. The usual clinical perspective is to equate consciousness with responsiveness, assuming functional motor responses and sympathetic activity of the patient. Clinical diagnoses of coma may be wrong in more
Michael Broomé, Tiit Mathiesen
wiley   +1 more source

Sedative-hypnotic drug use and risk of falls and fractures in elderly patients: a cross-sectional study. [PDF]

BMC Geriatr
Imani MH, Imani AH, Saem A, Niksolat M.
europepmc   +1 more source

Scn4b regulates the hypnotic effects of ethanol and other sedative drugs

, 2019
Yuri A. Blednov, Michal Bajo, Amanda J. Roberts, Adriana J. Da Costa, Mendy Black, Stephanie Edmunds, Jody Mayfield, Marisa Roberto, Gregg E. Homanics, Amy W. Lasek, Robert Hitzemann, R. Adron Harris   +11 more
openalex   +2 more sources

Comparative effectiveness of sodium‐glucose cotransporter‐2 inhibitors and glucagon‐like peptide‐1 receptor agonists for incident dementia: A retrospective multicohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1443-1452, February 2026.
Abstract Objective This study provides real‐world evidence on the comparative effectiveness of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) regarding the risk of incident dementia in adults with type 2 diabetes mellitus (T2DM).
Filippos Anagnostakis, Michail Kokkorakis, Shrihari Nagarajan, Georgia Anastasiou, Christos S. Mantzoros   +4 more
wiley   +1 more source

Nationwide trends in diagnosed sedative, hypnotic or anxiolytic use disorders in adolescents and young adults enrolled in Medicaid: 2001–2019 [PDF]

Greta Bushnell, Kristen Lloyd, Mark Olfson, Tobias Gerhard, Katherine M. Keyes, Magdalena Cerdá, Deborah S. Hasin   +6 more
openalex   +1 more source

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 172-185, January 2026.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, Manjunath S. Shet, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

Mediating effect of suicidality on influence of insomnia on favorable attitude to taking hypnotics among people in the general population complaining of insomnia. [PDF]

BMC Psychol
Ahn MH, Chung S.
europepmc   +1 more source

A drug education manual concerning illicit drugs and psychotropics - For teachers in secondary schools in the Member States of the European Community. Medicine. EUR 10594 EN [PDF]

, 1986
Basso, F., Casselman, J., Moorthamer, L., Van Hende, L.   +3 more
core  

L‐Quebrachitol Enhances Sedative Effect of Diazepam Through GABAergic Pathway: Animal and Computational Studies

Brain and Behavior, Volume 16, Issue 1, January 2026.
L‐quebrachitol (LQL) significantly enhanced the sedative effects of diazepam in thiopental sodium‐induced chicks by reducing sleep latency and prolonging duration. Molecular docking revealed LQL's interaction with GABAA receptor (α1 and β2 subunits), supporting a GABAergic mechanism and highlighting its potential as a safe, natural sedative agent ...
Asifa Asrafi, Mohammad Aslam, Md. Sakib Al Hasan, Mohammed Burhan Uddin, Emon Mia, Mohammad Y. Alshahrani, Sumaya Akter Bithi, Mst. Sumaia Akter, Md. Arif Hossain, Md. Torequl Islam   +9 more
wiley   +1 more source

Psychotropic Medication Exposure via Breast Milk: A Population-Based Descriptive Study in Denmark. [PDF]

Paediatr Perinat Epidemiol
Liu X, Madsen KB, Zhu JL, Munk-Olsen T, Damkier P, Lupattelli A, Zoega H, Nordeng H, Kjeldsen MZ, Mægbæk ML, Madsen MG, Bergink V, Bliddal M.   +12 more
europepmc   +1 more source