Results 211 to 220 of about 27,102 (328)

Pitolisant Inhibits Alcohol Drinking and Improves Withdrawal Negative Affect Through Lateral Habenula Histaminergic Signaling in Mice

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pitolisant, an FDA‐approved H3R antagonist, counteracts the rewarding and sedative effects of ethanol, reduces alcohol intake, and alleviates the negative affect during withdrawal. This might occur via the antagonism of presynaptic autoreceptors and heteroreceptors H3Rs in the lateral habenula, thereby activating the H2R/p‐CREB/BDNF signaling and ...
Yan Zhao   +13 more
wiley   +1 more source

Self-reported sleep duration and coronary heart disease mortality:A large cohort study of 400,000 Taiwanese adults [PDF]

open access: yes, 2016
Chang, Shu-Sen   +5 more
core   +1 more source

Exploring the Overlooked: Dutch Clinicians' Perspectives on Side Effects of Psychological Interventions

open access: yesClinical Psychology &Psychotherapy, Volume 33, Issue 1, January/February 2026.
ABSTRACT Steven J. Lynn (1946–2024) was a prolific researcher who explored a wide array of topics in clinical psychology. He and his co‐authors emphasized the importance of researching the side effects of psychological interventions. In the current studies (Study 1, N = 58; Study 2, N = 64), we examined clinicians' perspectives on side effects.
Sanne T. L. Houben   +3 more
wiley   +1 more source

The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review

open access: yesEuropean Eating Disorders Review, Volume 34, Issue 1, Page 55-70, January 2026.
ABSTRACT Objective Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals. Method A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025.
M. J. Besjes   +3 more
wiley   +1 more source

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

open access: yesFood Safety and Health, Volume 4, Issue 1, Page 220-232, January 2026.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh   +8 more
wiley   +1 more source

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