Results 221 to 230 of about 27,102 (328)

Long‐Term Effect of Acetylcholinesterase Inhibitors on Behavioral and Psychological Symptoms of Dementia

open access: yesInternational Journal of Geriatric Psychiatry, Volume 41, Issue 1, January 2026.
ABSTRACT Objective Behavioral and psychological symptoms of dementia (BPSD) are critical aspects of the clinical presentation of dementia. There is no universally accepted approach for the managment of BPSD, currently based first on a non‐pharmacological and subsequently on a pharmacological approach.
Giovanni Zuliani   +7 more
wiley   +1 more source

Anxiolytic Medication Use in Low‐ Middle‐ and High‐Income Countries: A World Mental Health Surveys Report

open access: yesHuman Psychopharmacology: Clinical and Experimental, Volume 41, Issue 1, January 2026.
ABSTRACT Background Anxiolytic medications, particularly benzodiazepines, are widely prescribed, giving impetus to long‐standing debates about how often these agents should be employed in clinical practice. There are, however, few cross‐country studies of the pharmacoepidemiology of these agents. We report on the frequency of anxiolytic medication use,
Dan J. Stein   +31 more
wiley   +1 more source

The V‐Shaped Hamilton Receptors: A Paradigmatic Multipurpose Scaffold

open access: yesChemistryOpen, Volume 15, Issue 1, January 2026.
This manuscript explores the historical context and significance of molecular recognition in relation to Hamilton‐type receptors. It concludes with a discussion on future prospects for the development of novel functionalized Hamilton‐type receptors. It is hoped that this collection will offer new insights and directions for the supramolecular chemistry
Shafieq Ahmad Wagay, Rashid Ali
wiley   +1 more source

Critical evaluation of real‐world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION Repurposing Food and Drug Administration (FDA)‐approved drugs could accelerate treatment development for Alzheimer's disease (AD). METHODS Using the MarketScan claims database (2011 to 2020), we applied a trial emulation approach in two base cohorts: (1) individuals with mild cognitive impairment (MCI cohort) and (2) individuals ...
Reina Tonegawa‐Kuji   +10 more
wiley   +1 more source

Implementation of geriatric clinical decision support in the emergency department for potentially inappropriate medications

open access: yesAcademic Emergency Medicine, Volume 33, Issue 1, January 2026.
Abstract Objectives The use of potentially inappropriate medications (PIMs) in older adults in the emergency department (ED) is associated with increased risk of readmissions and adverse drug reactions. We sought to assess the impact of electronic health record (EHR)‐based geriatric clinical decision support (CDS) on adherence to geriatric ...
Gina A. Elder   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy