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Anxiolytics, sedatives and hypnotics
Anaesthesia & Intensive Care Medicine, 2007Anxiolytics and sedatives are used in current anaesthetic practice for anxiolysis before surgery and as adjuvants during anaesthesia. The safety profile of these agents depends on their pharmacokinetic and pharmacodynamic profiles, patient comorbidity and the experience of the clinician.
Anthony Absalom, Caroline Meerts
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Critical Care Medicine, 1997
OBJECTIVE To clarify whether tumor necrosis factor (TNF)-alpha modulates the inhibitory effect of clinically applied hypnotics and sedatives on neutrophil function. DESIGN Prospective, randomized, controlled, dose response, in vitro study.
M. Weiss +3 more
semanticscholar +1 more source
OBJECTIVE To clarify whether tumor necrosis factor (TNF)-alpha modulates the inhibitory effect of clinically applied hypnotics and sedatives on neutrophil function. DESIGN Prospective, randomized, controlled, dose response, in vitro study.
M. Weiss +3 more
semanticscholar +1 more source
Sedative-hypnotics and human performance [PDF]
Psychopharmacology, 1982 In 52 studies, performance data were obtained the next day following bedtime ingestion of a sedative-hypnotic or a placebo. Only eight of these studies used insomniac patients. Most studies used young adult males. Benzodiazepine hypnotics were most frequently administered and psychomotor performance was most often measured.
Laverne C. Johnson +2 more
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The Clinical Choice of Sedative-Hypnotics
Annals of Internal Medicine, 1972Abstract The clinician is faced with a bewildering array of available sedatives, hypnotics, and tranquilizers, as well as continuous pressure from patients, the popular media, and the pharmaceutica...
David J. Greenblatt, Richard I. Shader
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