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Hypnotics and Sedatives [PDF]

open access: possible, 2021
Sleep is an active physiological process which harmonizes the brain function. A sedative is a drug which reduces activity and alertness by producing a calming effect on the subject, whereas a hypnotic induces drowsiness and promotes sleep onset and maintenance.
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Anxiolytics, sedatives and hypnotics

Anaesthesia & Intensive Care Medicine, 2007
Anxiolytics and sedatives are used in current anaesthetic practice for anxiolysis before surgery and as adjuvants during anaesthesia. The safety profile of these agents depends on their pharmacokinetic and pharmacodynamic profiles, patient comorbidity and the experience of the clinician.
Anthony Absalom, Caroline Meerts
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Sedative-hypnotics and human performance [PDF]

open access: possiblePsychopharmacology, 1982
In 52 studies, performance data were obtained the next day following bedtime ingestion of a sedative-hypnotic or a placebo. Only eight of these studies used insomniac patients. Most studies used young adult males. Benzodiazepine hypnotics were most frequently administered and psychomotor performance was most often measured.
Laverne C. Johnson   +2 more
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The Clinical Choice of Sedative-Hypnotics

Annals of Internal Medicine, 1972
Abstract The clinician is faced with a bewildering array of available sedatives, hypnotics, and tranquilizers, as well as continuous pressure from patients, the popular media, and the pharmaceutica...
David J. Greenblatt, Richard I. Shader
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SEDATIVES AND HYPNOTICS

Journal of Psychosocial Nursing and Mental Health Services, 1965
Psychiatric Drugs & ...
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Sedative and Hypnotic Drugs

2020
Anxiety and insomnia are the most commonly prevalent problems worldwide. These conditions affect the psychiatric, psychosocial, and medical wellbeing. Pharmacological agents by exerting calming and depressive effect on the central nervous system reduce anxiety and also induce the onset and maintenance of sleep.
Arup Kumar Misra, Pankaj Sharma
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Anxiolytics and sedative/hypnotics dependence

British Journal of Addiction, 1991
AbstractAnxiolytics and sedative/hypnotics are commonly used drugs. Benzodiazepines have largely replaced barbiturate and non‐barbiturate anxiolytics and sedative/hypnotics as they are as effective and safer. Experiments in laboratory animals have shown that chronic administration of benzodiazepines tested to date can induce physical dependence.
Usoa E. Busto, Edward M. Sellers
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Sedative Hypnotics

2014
The sedative hypnotic drugs represent a variety of chemical agents that depress central nervous system activity. They have many clinical uses in medicine including treatment of anxiety and insomnia, epilepsy, as muscle relaxants, and for induction of anesthesia. Some members of the class also possess significant abuse potential and a hazard of overdose
Mark A. Oldham, Domenic A. Ciraulo
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