Results 31 to 40 of about 1,460 (168)

Hypocitraturia Contributing to Nephrolithiasis in a Patient with CYP24A1 Gene Mutation [PDF]

AACE Clinical Case Reports, 2018
ABSTRACT: Objective: There have been several case reports of hypercalcemia due to mutation in CYP24A1, which encodes an enzyme that controls the catabolism of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D to inactive forms. These patients develop nephrolithiasis, nephrocalcinosis, and eventually renal insufficiency.
Mohamed K.M. Shakir, MD, Ibrahim al-Jabbar, MHS, Thanh D. Hoang, DO, Terry Shin, MD, Vinh Q. Mai, DO   +4 more
openaire   +2 more sources

Interpretable Machine Learning for Predicting Metabolic Syndrome–Kidney Stone Disease Comorbidity: The Role of Dietary Micronutrients

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study used NHANES 2007–2018 data to develop interpretable machine learning models for predicting MetS–KSD comorbidity using dietary micronutrients and demographic variables. Random Forest and XGBoost showed the best performance under different modeling strategies, and key dietary micronutrient predictors varied according to model context ...
Guanwei Wu, Haibo Qin, Junfeng Yao, Yingqing Liu, Jie Zheng, Jiawei Wang, Zongyao Hao, Lingsong Tao   +7 more
wiley   +1 more source

Determinants and impact of calcium oxalate crystal deposition on renal outcomes in acute kidney injury patients

Renal Failure
Objectives Calcium oxalate (CaOx) crystal deposition in acute kidney injury (AKI) patients is under recognized but impacts renal outcomes. This study investigates its determinants and effects.Methods We studied 814 AKI patients with native kidney ...
Weiwei Yang, Tao Zhao, Xuejing Chen, Suxia Wang, Yu Wang, Tao Su   +5 more
doaj   +1 more source

Kidney Stone, Nutritional Perceptions and Impact of Tea on Stone Formation

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
ABSTRACT The significant financial burden that urinary stone disease places on healthcare systems is only anticipated to increase over time. It is becoming more common over the globe. It is an increasing urinary condition that impacts around 12% of the global population, and environmental variables appear to be a key contributor.
Munir Ahmed, Danish Kamal, Umber Mubeen, Sakhawat Riaz, Amber Tehseen, Muhammad Mazahir   +5 more
wiley   +1 more source

Low bone mineral density is a potential risk factor for symptom onset and related with hypocitraturia in urolithiasis patients: a single-center retrospective cohort study

BMC Urology, 2020
Background Patients with urolithiasis have a lower bone mineral density (BMD) than those without stones, suggesting a potential correlation between calcium stone formation and bone resorption disorders, including osteopenia and osteoporosis.
Kazumi Taguchi, Shuzo Hamamoto, Atsushi Okada, Yutaro Tanaka, Teruaki Sugino, Rei Unno, Taiki Kato, Ryosuke Ando, Keiichi Tozawa, Takahiro Yasui   +9 more
doaj   +1 more source

Adenosine triphosphate citrate lyase mediates hypocitraturia in rats. [PDF]

Journal of Clinical Investigation, 1996
Chronic metabolic acidosis increases proximal tubular citrate uptake and metabolism. The present study addressed the effect of chronic metabolic acidosis on a cytosolic enzyme of citrate metabolism, ATP citrate lyase. Chronic metabolic acidosis caused hypocitraturia in rats and increased renal cortical ATP citrate lyase activity by 67% after 7 d. Renal
J Z, Melnick, P A, Srere, N A, Elshourbagy, O W, Moe, P A, Preisig, R J, Alpern   +5 more
openaire   +2 more sources

Rare Manifestation of Sjogren's Syndrome: Renal Tubular Acidosis‐Induced Hypokalemic Paralysis—A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Sjogren's syndrome (SS) is an autoimmune disorder characterized by inflammation of exocrine glands, often presenting with symptoms such as dry eyes and mouth. Although less common, renal involvement can lead to serious complications like hypokalemic paralysis.
Premendra Vimal, Dhiraj Chaurasia, Dipesh Jha, Raj Adhikari   +3 more
wiley   +1 more source

Tip 1 Glikojen Depo Hastalığı Olan Bir Çocukta Distal Renal Tübüler Disfonksiyon ve Kalsiyum Taş Hastalığı: Vaka Sunumu

Turkish Journal of Nephrology, 2019
Type 1 glycogen storage disease is caused by glucose-6-phosphatase deficiency and nephrolithiasis is the most common renal complication. Although urate stones are the most common stone type, metabolic alterations favoring calcium nephrolithiasis has also
Yeşim ÖZTÜRK, Uluç YİŞ, Alper SOYLU, Mehmet TÜRKMEN, Salih KAVUKÇU, Benal BÜYÜKGEBİZ   +5 more
doaj   +2 more sources

Identifying recurrent stone formers with machine learning: A single‐centre observational study

BJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objectives Kidney stones affect 12% of the population over their lifetime. Recurrent kidney stones lead to repeated interventions and excessive healthcare costs. Despite progress in imaging and metabolic evaluations, models to accurately identify patients at high risk are missing.
Pedro Amado, Daniel G. Fuster, Matteo Bargagli, Dominik Obrist, Fiona Burkhard, Beat Roth, Francesco Clavica, Shaokai Zheng   +7 more
wiley   +1 more source

Case report: disease mechanisms and medical management of calcium nephrolithiasis in rheumatologic diseases

BMC Urology, 2023
Background Nephrolithiasis as a feature of rheumatologic diseases is under recognized. Understanding presenting features, diagnostic testing is crucial to proper management.
Omar Osman, Susan Manzi, Mary Chester Wasko, Barbara A. Clark   +3 more
doaj   +1 more source