Results 51 to 60 of about 4,005 (184)

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source

Lived Experiences of Tooth Hypersensitivity in Children With Molar Incisor Hypomineralisation

International Journal of Paediatric Dentistry, Volume 36, Issue 4, Page 605-616, July 2026.
ABSTRACT Background Children with molar incisor hypomineralisation (MIH) can suffer from intense tooth hypersensitivity (TH), which may adversely affect various aspects of their emotional, social, and functional wellbeing. As TH diagnostic tools are primarily adapted from adult research, there is a clear need for a deeper understanding of MIH‐TH from a
Joana Monteiro, Fiona Gilchrist, Helen Rodd   +2 more
wiley   +1 more source

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple, Sotiria Gizani, Mariano Sanz, Dominique Declerck, Phoebus Madianos, Valerie Clerehugh, Monique Danser, Esti Davidovich, Janet Davies, Nikos Donos, Elisabeth Dursun, Elena Figuero, Filippo Graziani, Mervi Gursoy, Soren Jepsen, Clara Joseph, Moritz Kebschull, Norbert Kraemer, Tina Lambrinaki, Rodrigo López, David J. Manton, Joerg Meyle, Ana Molina, Lior Shapira, Cheryl Somani, Georgios Tsilingaridis, Svante Twetman, Nicola West, Biniyam Wondimu, Ferranti Wong, David Herrera   +30 more
wiley   +1 more source

The role of PAX9 promoter gene polymorphisms in causing hypodontia: a study in the Jordanian population

The Application of Clinical Genetics, 2018
Ahmed Abu-Siniyeh,1 Omar F Khabour,1 Arwa I Owais2 1Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Applied Dental Sciences, Faculty of Applied ...
Abu-Siniyeh A, Khabour OF, Owais AI
doaj  

Two‐Year Follow‐Up of Ectodermal Dysplasia‐Syndactyly Syndrome 1 in a Palestinian Child Successfully Treated With Topical Minoxidil and Tretinoin: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Clinical timeline of the reported EDSS1 case, illustrating disease onset, diagnostic milestones, treatment initiation, treatment modifications, and longitudinal response to combined topical minoxidil and tretinoin therapy from infancy through the last follow‐up.
Bana O. Aburajab, Hamza M. A. Ghaith, Nada Ishti, Muawia O. Aburajab   +3 more
wiley   +1 more source

Non‐Isolated Dandy‐Walker Malformation: Exome Sequencing Efficacy and Phenotypic Expansions

Clinical Genetics, Volume 109, Issue 6, Page 1029-1037, June 2026.
Exome sequencing identified a diagnosis in 35% of 91 individuals with non‐isolated Dandy Walker malformation (DWM+). Only 24%–55% of these diagnoses could be made using a gene panel. We then demonstrated that DWM is a feature of disorders associated with ANKRD11, C2CD3, COL4A1, KMT2D, KRAS, OPHN1, SHOC2, SMARCB1, and WDR73.
Sarah Araji, Xiaonan Zhao, Jill A. Rosenfeld, Seema R. Lalani, Daryl A. Scott   +4 more
wiley   +1 more source

Comparison of Oral Health Related Quality of Life (OHRQoL) in Hypodontia Patients and Patients with Acquired Missing Teeth

Journal of Nobel Medical College, 2017
Background: Hypodontia is the developmental absence of one or more teeth from the dentition whereas acquired missing teeth are those lost due to carries, periodontal problem or dental trauma.
Shanti Chhetri, Muhammad Waseem Ullah Khan, Nazia Yazdanie   +2 more
doaj   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

The prevalence and distribution of hypodontia inorthodontic patients in Bosnia and Herzegovina

Journal of Health Sciences
Introduction: The need for this study on the prevalence of hypodontia in a sample of orthodontic patients from Bosnia and Herzegovina arises from the fact that in the state of Bosnia and Herzegovina, there is a lack of data on the prevalence and ...
Azra Jelešković, Indira Mujić Jahić, Aida Selmanagić, Sara Mujić, Lejla Redžepagić Vražalica   +4 more
doaj   +1 more source

Evaluation of third molar agenesis associated with hypodontia and oligodontia in turkish pediatric patients

European Oral Research, 2020
Purpose To evaluate the association between third molar (M3) agenesis and hypodontia and oligodontia in pediatric patients by using panoramic radiography.Materials and Methods Panoramic radiographs of 1,471 patients (899 females; 572 males) and 5,884 ...
Meltem Tekbaş Atay, Neslihan Özveren, Gözde Serindere   +2 more
doaj   +1 more source