Results 91 to 100 of about 41,302 (312)

Evaluating the Combination of Human Chorionic Gonadotropin and Clomiphene Citrate in Treatment of Male Hypogonadotropic Hypogonadism: A Prospective Study

Research and Reports in Urology, 2021
The Son Trinh,1 Nguyen Ba Hung,2,3 Le Thi Thu Hien,2 Ngo Anh Tuan,4 Dinh Cong Pho,5 Quan Anh Dung,6 Duc Anh Do,7 Ha Duc Quang,2 Hoang Van Ai,1 Pham Ngoc Hung8,9 1Military Institute of Clinical Embryology and Histology, Vietnam Military Medical University,
Trinh TS, Hung NB, Hien LTT, Tuan NA, Pho DC, Dung QA, Do DA, Quang HD, Ai HV, Hung PN   +9 more
doaj  

Effect of Testosterone on FGF2, MRF4, and Myostatin in Hypogonadotropic Hypogonadism: Relevance to Muscle Growth.

Journal of Clinical Endocrinology and Metabolism, 2019
CONTEXT Fibroblast growth factor (FGF)2 is an important stimulatory modulator of satellite cells in skeletal muscle. Satellite cells play a cardinal role in muscle growth and repair. OBJECTIVE We evaluated whether skeletal muscle expression of FGF2 and
H. Ghanim, S. Dhindsa, M. Batra, K. Green, S. Abuaysheh, Nitesh D Kuhadiya, A. Makdissi, A. Chaudhuri, P. Dandona   +8 more
semanticscholar   +1 more source

Primary Partial Empty Sella presenting with Prepubertal Hypogonadotropic Hypogonadism

Journal of the ASEAN Federation of Endocrine Societies, 2020
Primary partial empty sella occurs when less than 50% of an enlarged or deformed sella turcica is filled with cerebrospinal fluid in the setting of unidentified etiologic pathological conditions.
Maria Angela Matabang, Buena Sapang
doaj   +1 more source

Genetic Regulation of Puberty Timing in Humans. [PDF]

, 2015
Understanding the regulation of puberty timing has relevance to developmental and human biology and to the pathogenesis of various diseases. Recent large-scale genome-wide association studies on puberty timing and adult height, body mass index (BMI) and ...
Day, Felix R, Ong, Ken K, Perry, John RB
core   +2 more sources

ODP401 A new FGFR1 mutation causing Idiopathic Hypogonadotropic Hypogonadism and Polydactyly [PDF]

, 2022
Luis Borges Espinosa, Alejandro Ayala, Daniela Dicenso   +2 more
openalex   +1 more source

Puberty‐Promoting Treatment and Psychosocial Well‐Being in Boys With Constitutional Delay of Puberty: A Randomized Controlled Trial

Clinical Endocrinology, Volume 104, Issue 2, Page 139-146, February 2026.
ABSTRACT Objective In boys, constitutional delay of growth and puberty (CDGP) has been associated with diverse negative psychosocial effects. Albeit alleviating distress is one of the main reasons for inducing pubertal development, the impact of puberty‐promoting treatment on psychosocial wellbeing is under‐researched.
Laura Kariola, Tero Varimo, Mitja Lääperi, Hanna Huopio, Sirpa Tenhola, Raimo Voutilainen, Jorma Toppari, Silja Kosola, Päivi J. Miettinen, Olli Raitakari, Marko Elovainio, Taneli Raivio, Matti Hero   +12 more
wiley   +1 more source

Hypogonadism in thalassemia major patients

Journal of Clinical & Translational Endocrinology, 2016
Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients.
Sasima Srisukh, Boonsong Ongphiphadhanakul, Pongamorn Bunnag   +2 more
doaj   +1 more source

Haploinsufficiency of Dmxl2, Encoding a Synaptic Protein, Causes Infertility Associated with a Loss of GnRH Neurons in Mouse [PDF]

, 2014
International audienceCharacterization of the genetic defects causing gonadotropic deficiency has made a major contribution to elucidation of the fundamental role of Kisspeptins and Neurokinin B in puberty onset and reproduction.
Carel, Jean-Claude, Charles, Perrine, Chevenne, Didier, Csaba, Zsolt, de Roux, Nicolas, Dupont, Joelle, Genin, Emmanuelle, Huijbregts, Lukas, Jacquier, Sandrine, Leka, Sofia, Léger, Juliane, Meyer, Vincent, Tata, Brooke   +12 more
core   +7 more sources

Functional Hypogonadotropic Hypogonadism in Men: Underlying Neuroendocrine Mechanisms and Natural History.

Journal of Clinical Endocrinology and Metabolism, 2019
CONTEXT After completion of puberty a subset of men experience functional hypogonadotropic hypogonadism (FHH) secondary to excessive exercise or weight loss.
A. Dwyer, N. Chavan, Hilana M Lewkowitz-Shpuntoff, L. Plummer, F. Hayes, S. Seminara, W. Crowley, N. Pitteloud, Ravikumar Balasubramanian   +8 more
semanticscholar   +1 more source

Identification and Functional Characterization of a Novel SEMA3A Exon Deletion Variant in Kallmann Syndrome

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
The study identified a novel SEMA3A exons 6–9 deletion variant in Kallmann syndrome that impairs GnRH neuronal migration and alters cell migration, gonad development, and synaptic pathways. The study expands mutation spectrum and offers mechanistic insights for clinical diagnosis of Kallmann syndrome.
Shaolian Zang, Shasha Zhou, Qingxu Liu, Xiaoqin Yin, Pin Li   +4 more
wiley   +1 more source