Results 91 to 100 of about 30,173 (242)

Endocrine Aspects of 4H Leukodystrophy: A Case Report and Review of the Literature

Case Reports in Endocrinology, 2015
Introduction. 4H leukodystrophy is an autosomal recessive RNA polymerase III-related leukodystrophy, characterized by hypomyelination, with or without hypodontia (or other dental abnormalities) and hypogonadotropic hypogonadism. Case Presentation.
Emma Billington, Geneviève Bernard, William Gibson, Bernard Corenblum   +3 more
doaj   +1 more source

Neuroendocrine mechanisms responsible for elevated gonadotrophin‐releasing hormone and luteinising hormone pulses in polycystic ovary syndrome

Journal of Neuroendocrinology, EarlyView.
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley   +1 more source

Optimal treatment for spermatogenesis in male patients with hypogonadotropic hypogonadism

Medicine, 2019
Background: To compare the efficacies of gonadotropin-releasing hormone (GnRH) pulse subcutaneous infusion with combined human chorionic gonadotropin and human menopausal gonadotropin (HCG/HMG) intramuscular injection have been performed to treat male ...
Jianli Lin, J. Mao, Xi Wang, Wanlu Ma, M. Hao, Xueyan Wu   +5 more
semanticscholar   +1 more source

Rare case of chiasm glioma in woman with hypogonadotropic hypogonadism and obesity

Mìžnarodnij Endokrinologìčnij Žurnal, 2017
Chiasm glioma is a rare disease characterized by a decrease in the visual field. The aim of research was to describe a clinical case of chiasm glioma with concomitant hypogonadism and obesity.
M.B. Abduvakhabova
doaj   +1 more source

Association of Deficiency in Vitamin D, Vitamin E, and Selenium Levels With Premature Ovarian Insufficiency: A Systematic Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background Regular levels of reactive oxygen species (ROS) are essential for regulating the growth and activity of ovarian follicles, very high levels can lead to accelerated oxidative stress, which in turn causes premature ovarian insufficiency (POI) and reproductive dysfunction. Objectives This systematic review aimed to assess the impact of
Farideh Pargar, Maryam Farjamfar, Shahrbanoo Goli, Zeinab Rabiei, Zahra Motaghi   +4 more
wiley   +1 more source

Testosterone replacement in congenital hypogonadotropic hypogonadism maintains bone density but has only limited osteoanabolic effects

Andrology, 2019
Congenital hypogonadotropic hypogonadism (CHH) is a rare condition characterized by complete sex steroid deficiency. Therefore, CHH is a unique human model to study the impact of long‐term testosterone replacement therapy (TRT) on bone.
L. Antonio, S. Caerels, F. Jardi, E. Delaunay, Dirk Vanderschueren   +4 more
semanticscholar   +1 more source

Endocrine Abnormalities and Growth Pattern in Single Large‐Scale Mitochondrial DNA Deletion Syndromes

Acta Paediatrica, Volume 114, Issue 8, Page 1857-1867, August 2025.
ABSTRACT Aim To assess the prevalence of endocrine disorders and investigate growth patterns in single large‐scale mitochondrial DNA deletion syndromes (SLSMDs). Methods A retrospective study of all children with SLSMD who attended Sheba Medical Center, Israel, from February 2017 to September 2024.
Ayman Daka, Einat Lahav, Omer Bar Yosef, Yoav Bolkier, Yael Levy‐Shraga, Yair Anikster, Elad Jacoby, Noah Gruber   +7 more
wiley   +1 more source

Evaluation of gonadotropin-replacement therapy in male patients with hypogonadotropic hypogonadism

Asian Journal of Andrology, 2019
Hypogonadotropic hypogonadism (HH) is a rare disease in which medical treatment has a high success rate to achieve fertility. This study aimed to analyze the efficacy of hormone replacement therapy and determine predictive factors for successful ...
M. Ortaç, M. Hıdır, E. Salabaş, A. Boyuk, Caner Beşe, Y. Pazır, A. Kadıoğlu   +6 more
semanticscholar   +1 more source

Androgen Receptor Gene CAG Repeat Polymorphism Regulates the Metabolic Effects of Testosterone Replacement Therapy in Male Postsurgical Hypogonadotropic Hypogonadism

International Journal of Endocrinology, 2013
Aim. To evaluate the independent role of androgen receptor (AR) gene CAG repeat polymorphism on metabolic effects of testosterone replacement therapy (TRT) in male postsurgical hypogonadotropic hypogonadism, a condition frequently associated with ...
Giacomo Tirabassi, Nicola delli Muti, Giovanni Corona, Mario Maggi, Giancarlo Balercia   +4 more
doaj   +1 more source

DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development

Human Molecular Genetics, 2018
Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disease characterized by absent puberty and infertility due to GnRH deficiency, and is often associated with anosmia [Kallmann syndrome (KS)].
J. Bouilly, A. Messina, Georgios E. Papadakis, Daniele Cassatella, Cheng Xu, J. Acierno, B. Tata, G. Sykiotis, S. Santini, Y. Sidis, É. Elowe-Gruau, F. Phan‐Hug, M. Hauschild, P. Bouloux, R. Quinton, M. Lang-Muritano, L. Favre, Laura Marino, P. Giacobini, A. Dwyer, N. Niederländer, N. Pitteloud   +21 more
semanticscholar   +1 more source