Results 101 to 110 of about 41,302 (312)

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? Episode II: Empathy

open access: yesAndrology, Volume 14, Issue 1, Page 273-283, January 2026.
Abstract The exploration of gender differences in non‐andrological fields was the core focus of a series of discussions, which took place at the Endocrinology Unit in Modena, Italy in the form of the aporetic dialogue of ancient Greece. This second episode reports the transcript of the actual debate on testosterone's role in defining empathic behavior ...
Giulia Brigante   +6 more
wiley   +1 more source

CCDC141 Mutations in Idiopathic Hypogonadotropic Hypogonadism [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2017
Gonadotropin-releasing hormone neurons originate outside the central nervous system in the olfactory placode and migrate into the central nervous system, becoming integral components of the hypothalamic-pituitary-gonadal axis. Failure of this migration can lead to idiopathic hypogonadotropic hypogonadism (IHH)/Kallmann syndrome (KS). We have previously
Turan, Ihsan   +9 more
openaire   +3 more sources

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, Volume 14, Issue 1, Page 210-227, January 2026.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

Hypogonadotropic hypogonadism due to compound heterozygous mutations TACR3 in siblings

open access: yesClinical Case Reports, 2020
The authors present a new association of two heterozygous TACR3 mutations (p.Arg230His and p.Trp275*) responsible for a clinical trait of normosmic congenital hypogonadotropic hypogonadism in a family.
Rita Valsassina   +4 more
doaj   +1 more source

Food and the brain: Neural and endocrine control of feeding, metabolism, and reproduction

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Feeding and reproductive function are regulated by intricate systems that monitor food availability and energy stores, and on the basis of energy status, promote or put a brake on reproduction. This is particularly evident in the systems that regulate feeding and reproductive state in female mammals.
Naira da Silva Mansano   +2 more
wiley   +1 more source

An ancient founder mutation in PROKR2 impairs human reproduction [PDF]

open access: yes, 2017
Congenital gonadotropin-releasing hormone (GnRH) deficiency manifests as absent or incomplete sexual maturation and infertility. Although the disease exhibits marked locus and allelic heterogeneity, with the causal mutations being both rare and private ...
Abreu, Ana Paula   +22 more
core  

Testosterone replacement in congenital hypogonadotropic hypogonadism maintains bone density but has only limited osteoanabolic effects

open access: yesAndrology, 2019
Congenital hypogonadotropic hypogonadism (CHH) is a rare condition characterized by complete sex steroid deficiency. Therefore, CHH is a unique human model to study the impact of long‐term testosterone replacement therapy (TRT) on bone.
L. Antonio   +4 more
semanticscholar   +1 more source

Magnetic resonance imaging features of hypophysitis in patients with cancer treated with immune checkpoint inhibitors

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
This study evaluated pituitary MRI results in cancer patients who experienced immune‐related hypophysitis while receiving immune checkpoint inhibitor treatment. MRI abnormalities were present in 63% of patients at follow‐up and 56% of patients at diagnosis, mostly in patients with multiple hormonal deficiencies.
Anna Angelousi   +10 more
wiley   +1 more source

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