Results 111 to 120 of about 41,302 (312)
High frequency of CHD7 mutations in congenital hypogonadotropic hypogonadism
Scientific Reports, 2019 Congenital hypogonadotropic hypogonadism (CHH) is characterized by lack of normal pubertal development due to deficient gonadotropin-releasing hormone (GnRH) secretion or action, and is caused by genetic defects in several genes.
Catarina I. Gonçalves +9 more
semanticscholar +1 more source
Metabolic and appetitive regulation of adipocyte mass during treatment of obesity
Journal of Internal Medicine, Volume 299, Issue 1, Page 66-78, January 2026.Abstract Adipose mass is homeostatically maintained within a narrow range despite fluctuations in daily calorie intake and activity levels. Constituting an adipose mass “set point,” this homeostatic regulation includes sensing mechanisms in the form of hormones reflecting caloric intake that serve as mediators of appetitive behaviors and adipose mass ...
Jonathan Q. Purnell, Carel W. Le Roux
wiley +1 more source
PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders. [PDF]
, 2016 Prohormone convertase 1/3, encoded by the PCSK1 gene, is a serine endoprotease that is involved in the processing of a variety of proneuropeptides and prohormones. Humans who are homozygous or compound heterozygous for loss-of-function mutations in PCSK1
core +2 more sources
Evaluation of gonadotropin-replacement therapy in male patients with hypogonadotropic hypogonadism
Asian Journal of Andrology, 2019 Hypogonadotropic hypogonadism (HH) is a rare disease in which medical treatment has a high success rate to achieve fertility. This study aimed to analyze the efficacy of hormone replacement therapy and determine predictive factors for successful ...
M. Ortaç +6 more
semanticscholar +1 more source
Obesity Reviews, Volume 27, Issue 1, Page 1-21, January 2026.ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang +5 more
wiley +1 more source
Endocrine Aspects of 4H Leukodystrophy: A Case Report and Review of the Literature
Case Reports in Endocrinology, 2015 Introduction. 4H leukodystrophy is an autosomal recessive RNA polymerase III-related leukodystrophy, characterized by hypomyelination, with or without hypodontia (or other dental abnormalities) and hypogonadotropic hypogonadism. Case Presentation.
Emma Billington +3 more
doaj +1 more source
Rare case of chiasm glioma in woman with hypogonadotropic hypogonadism and obesity
Mìžnarodnij Endokrinologìčnij Žurnal, 2017 Chiasm glioma is a rare disease characterized by a decrease in the visual field. The aim of research was to describe a clinical case of chiasm glioma with concomitant hypogonadism and obesity.
M.B. Abduvakhabova
doaj +1 more source
Optimal treatment for spermatogenesis in male patients with hypogonadotropic hypogonadism
Medicine, 2019 Background: To compare the efficacies of gonadotropin-releasing hormone (GnRH) pulse subcutaneous infusion with combined human chorionic gonadotropin and human menopausal gonadotropin (HCG/HMG) intramuscular injection have been performed to treat male ...
Jianli Lin +5 more
semanticscholar +1 more source
Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.Adrenal insufficiency (AI) is characterized by inadequate steroid hormone production and is frequently a consequence of hypopituitarism, which is also associated with increased risk of osteoporosis due to deficiencies in growth hormone, gonadotropins, and other pituitary hormones.
Abrar Mohammed AlFaifi +2 more
wiley +1 more source
International Journal of Endocrinology, 2013 Aim. To evaluate the independent role of androgen receptor (AR) gene CAG repeat polymorphism on metabolic effects of testosterone replacement therapy (TRT) in male postsurgical hypogonadotropic hypogonadism, a condition frequently associated with ...
Giacomo Tirabassi +4 more
doaj +1 more source