Results 121 to 130 of about 41,302 (312)

Novel Leptin Receptor Mutations Identified in Two Girls with Severe Obesity Are Associated with Increased Bone Mineral Density [PDF]

, 2016
Background: Recessive mutations in the leptin receptor (LEPR) are a rare cause of hyperphagia and severe early-onset obesity. To date, the phenotype has only been described in 25 obese children, some of whom also had altered immune function ...
Bakker, E. (Egbert), Bik, E.C. (Elsa), Delemarre-van de Waal, H.A. (Henriette), Haeringen, A. (Arie) van, Hannema, S.E. (Sabine), Houdijk, E.C.A.M. (Mieke), Kant, S.G. (Sarina), Losekoot, M. (Monique), Oostdijk, W. (Wilma), Uitterlinden, A.G. (André), Verkerk, A., Wit, J.M. (Jan M.)   +11 more
core   +1 more source

Physical activity counteracts metabolic syndrome-induced hypogonadotropic hypogonadism and erectile dysfunction in the rabbit.

American Journal of Physiology. Endocrinology and Metabolism, 2019
Metabolic syndrome (MetS) clusters cardiovascular and metabolic risk factors along with hypogonadism and erectile dysfunction. Lifestyle modifications including physical exercise (PhyEx) are well-known treatments for this condition.
A. Morelli, S. Filippi, P. Comeglio, E. Sarchielli, I. Cellai, M. Pallecchi, G. Bartolucci, G. Danza, G. Rastrelli, C. Corno, G. Guarnieri, Elisa Fuochi, L. Vignozzi, M. Maggi   +13 more
semanticscholar   +1 more source

Utilidad de la hormona anti-mülleriana (AMH) y la inhibina B en el diagnóstico del hipogonadismo en el niño [PDF]

, 2014
Durante la infancia, el eje hipotálamo-hipófiso-testicular se encuentra parcialmente quiescente: bajan los niveles de gonadotrofinas y la secreción de testosterona disminuye siguiendo a la caída de la LH.
Ambao, Veronica Ana, Bedecarras, Patricia Gladys, Bergadá, Ignacio, Braslavsky, Débora, Campo, Stella Maris, Gottlieb, Silvia Elisa, Grinspon, Romina, Loreti, Nazareth, Rey, Rodolfo Alberto   +8 more
core   +1 more source

Defective migration of neuroendocrine GnRH cells in human arrhinencephalic conditions [PDF]

, 2010
Patients with Kallmann syndrome (KS) have hypogonadotropic hypogonadism caused by a deficiency of gonadotropin-releasing hormone (GnRH) and a defective sense of smell related to olfactory bulb aplasia.
Anne-Lise Delezoide, Catherine Dodé, Catherine Fallet-Bianco, Delezoide, Dodé, Fabien Guimiot, Falardeau, Hardelin, Jean-Pierre Hardelin, Luis Teixeira, Pagon, Pitteloud, Robert P. Millar   +12 more
core   +2 more sources

Congenital hypogonadotropic hypogonadism and constitutional delay of growth and puberty have distinct genetic architectures

European Journal of Endocrinology, 2018
Objective Congenital hypogonadotropic hypogonadism (CHH) and constitutional delay of growth and puberty (CDGP) represent rare and common forms of GnRH deficiency, respectively.
Daniele Cassatella, S. Howard, J. Acierno, Cheng Xu, Georgios E. Papadakis, F. Santoni, A. Dwyer, S. Santini, G. Sykiotis, Caroline Chambion, J. Meylan, Laura Marino, L. Favre, Jian-kang Li, Xuanzhu Liu, Jianguo Zhang, P. Bouloux, C. Geyter, A. Paepe, W. Dhillo, Jean-Marc Ferrara, M. Hauschild, M. Lang-Muritano, J. Lemke, C. Flück, A. Németh, F. Phan‐Hug, D. Pignatelli, V. Popović, S. Pekic, R. Quinton, G. Szinnai, D. l'Allemand, D. Konrad, S. Sharif, Ö. T. Iyidir, Brian J. Stevenson, Huanming Yang, L. Dunkel, N. Pitteloud   +39 more
semanticscholar   +1 more source

Lower sperm DNA fragmentation after r-FSH administration in functional hypogonadotropic hypogonadism [PDF]

, 2013
PURPOSE: An observational clinical and molecular study was designed to evaluate the effects of the administration of recombinant human FSH on sperm DNA fragmentation in men with a non-classical form of hypogonadotropic hypogonadism and idiopathic ...
BOSCO, Liana, Brucculeri, AM, Cittadini, E, Longobardi, S, ROCCHERI, Maria Carmela, Ruvolo, G   +5 more
core   +1 more source

INFERTILITY IN MEN WITH PRIMARY HYPOGONADOTROPIC HYPOGONADISM

Андрология и генитальная хирургия, 2017
In this study, an analysis data on the etiology, pathogenesis, diagnosis and treatment of male sterility with hypogonadotropic hypogonadism. Examination of the patients requires attention of urologist, andrologist, endocrinologist, neurosurgeon, medical ...
O. B. Zhukov, L. I. Astafieva, S. V. Blinova   +2 more
doaj   +1 more source

Low Degree of Overlap Between Kisspeptin, Neurokinin B, and Dynorphin Immunoreactivities in the Infundibular Nucleus of Young Male Human Subjects Challenges the KNDy Neuron Concept. [PDF]

, 2012
Previous immunohistochemical and in situ hybridization studies of sheep, goats, and rodents indicated that kisspeptin (KP), neurokinin B (NKB), and dynorphin A (DYN) are extensively colocalized in the hypothalamic arcuate nucleus, thus providing a basis ...
Borsay, Beáta Ágnes, Ciofi, Philippe, Gergely, Péter, Herczeg, László, Hrabovszky, Erik, Liposits, Zsolt, Molnár, Csilla, Sipos, Máté   +7 more
core   +1 more source

Clinical approach to the male with delayed puberty [PDF]

Archives of Endocrinology and Metabolism
Disorders of pubertal onset and progression are a common cause for referral to paediatric endocrinologists, with delayed puberty in males being particularly frequent. Pubertal development depends on the hypothalamic-pituitary-testicular (HPT) axis, which
Rodolfo A. Rey, Romina P. Grinspon, Sebastián Castro   +2 more
doaj   +1 more source

Delayed-onset adrenal hypoplasia congenita and hypogonadotropic hypogonadism caused by a novel mutation in

Journal of International Medical Research, 2020
In this study, we described a male who presented with delayed-onset adrenal hypoplasia congenita (AHC) and mild hypogonadotropic hypogonadism (HHG) without a relevant family history. A novel mutation in the DAX1 (dosage-sensitive sex reversal, congenital
Siyue Liu, Libin Yan, Xinrong Zhou, Chen Chen, Daowen Wang, Gang Yuan   +5 more
doaj   +1 more source