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Genetics of Hypogonadotropic Hypogonadism
Hormone Research in Paediatrics, 2007<i>Background:</i> Idiopathic hypogonadotropic hypogonadism (HH) results from a defect in the normal pulsatile secretion pattern of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Clinically it can be categorized as one of two types: HH associated with anosmia, known as Kallmann syndrome, and isolated HH.
SIMONI, Manuela, NIESCHLAG E.
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Genetics of hypogonadotropic hypogonadism
Journal of Endocrinological Investigation, 2000Determining the physiologic influences that modulate GnRH secretion, the prime initiator of reproductive function in the human, is fundamental not only to our understanding of the rare condition of congenital idiopathic hypogonadotropic hypogonadism (IHH), but also common disorders such as constitutional delay of puberty and hypothalamic amenorrhea ...
S B, Seminara +4 more
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Hypogonadotropic Hypogonadism from Osteopetrosis
Clinical Orthopaedics and Related Research, 1982A 47-year-old man with acquired hypogonadism of at least 15 years' duration was successfully treated with chorionic gonadotropin. Endocrine studies performed before and two months after discontinuation of gonadotropin therapy showed a decrease in serum testosterone level without secondary rise in serum gonadotropins.
J, Mazur, J, Wortsman
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Different Medications for Hypogonadotropic Hypogonadism
2015Delayed puberty (DP) in boys is the lack of sexual maturation at a chronological age of 14 years. Several conditions induce DP and they can be classified into reversible and irreversible causes. The most common cause of DP is constitutional delay of puberty (CDP; 63%), followed by DPs due to functional hypogonadotropic hypogonadism (HH; 20 ...
RASTRELLI, GIULIA +2 more
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Molecular causes of hypogonadotropic hypogonadism
Current Opinion in Obstetrics & Gynecology, 2010What controls puberty remains largely unknown and current gene mutations account for only about one-third of the apparently genetic cases of idiopathic hypogonadotropic hypogonadism. Lately important developments have occurred in this field.Substantial variation in clinical expression, from complete anosmia and hypogonadotropic hypogonadism to delayed ...
Ali Kemal, Topaloglu, Leman Damla, Kotan
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Predicting hypogonadotropic hypogonadism persistence in male macroprolactinoma
Pituitary, 2022Yaron Rudman +4 more
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Reversal of Idiopathic Hypogonadotropic Hypogonadism
New England Journal of Medicine, 2007Idiopathic hypogonadotropic hypogonadism, which may be associated with anosmia (the Kallmann syndrome) or with a normal sense of smell, is a treatable form of male infertility caused by a congenital defect in the secretion or action of gonadotropin-releasing hormone (GnRH).
Raivio T +11 more
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Post-traumatic selective hypogonadotropic hypogonadism
Journal of Endocrinological Investigation, 1997A very small proportion of hypopituitarism is due to head trauma, which may have occurred from days to years earlier. In the literature we found only three cases (two males, one female) of post-traumatic hypopituitarism in whom the hormone deficiency was claimed to be restricted to the gonadotrophs and considered to be permanent after a period of ...
BENVENGA, Salvatore +4 more
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The Genetics of Hypogonadotropic Hypogonadism
Seminars in Reproductive Medicine, 2007An up-to-date review of the genetic aspects of idiopathic hypogonadotropic hypogonadism (IHH)/Kallmann syndrome (KS) is presented. Because proper development of the neuroendocrine axis must occur for normal puberty and reproductive function, gonadotropin-releasing hormone (GnRH) neuron migration is outlined first, followed by an introduction to the in ...
Balasubramanian, Bhagavath +1 more
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A review of hypogonadotropic hypogonadism cases followed up in our clinic in the last decade
Urologiâ, 2019Introduction: The aim of the present study was to evaluate, with this retrospective study, the patients with hypogonadotropic hypogonadism, who were followed up in our clinic in the last decade and were reviewed in terms of the incidence of the disease ...
Fatih Kursat Yılmazel +5 more
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