Results 71 to 80 of about 10,779 (211)
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery +3 more
wiley +1 more source
Background and Purpose: QT prolongation and intracellular Ca 2+ loading with diastolic Ca 2+ release via ryanodine receptors (RyR2) are the predominant mechanisms underlying hypokalaemia-induced ventricular arrhythmia.
Freeman, Sally; id_orcid +11 more
core +1 more source
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid +17 more
wiley +1 more source
Primary Sjogren’s syndrome manifesting as recurrent hypokalemia with distal renal tubular acidosis
Sjogren’s syndrome is an autoimmune disease with both glandular and extraglandular manifestations. We report a rare case of primary Sjogren syndrome without sicca symptoms presenting with renal tubular acidosis and recurrent hypokalaemia.
Ajeya Kashyap +3 more
doaj +1 more source
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Liquorice-induced hypertension and hypokalaemia
Consumption of large amounts of liquorice can cause hypertension and hypokalaemia. Liquorice contains glycyrrhetinic acid, which inhibits the enzyme 11 beta-hydroxysteroid dehydrogenase type 2, and ultimately leads to an apparent mineralocorticoid excess
Andersen, Inger +2 more
core +1 more source
A rare case of Sjogren’s syndrome presenting as acute quadriparesis
We report the case of a 23-year-old female who presented with multiple episodes of vomiting and loose stools for 2 days, followed by rapidly progressive quadriparesis for 1 day.
M. C. R. Rama +3 more
doaj +1 more source
Seizure and Profound Hypokalemia: Unusual Presentation of Primary Hyperparathyroidism
: A 68-year-old man was admitted because of tonic–clonic convulsion. He had been receiving 200 mg itraconazole for 10 days. He had hypokalaemia (2.2 mEq/l), hypercalcaemia (Cacorr 11.0 mg/dl) and elevated serum parathyroid hormone (PTH, 95 pg/ml ...
Yasuto Nakasone +4 more
doaj +1 more source
Determinants of new-onset atrial fibrillation in a multidisciplinary critical care unit [PDF]
Background: The presence of New-onset Atrial Fibrillation (NOAF) during critical illness increases morbidity, mortality, and hospital costs, as well as the incidence of complications such as heart failure and thromboembolic disorders.
Sabu Aiwa +5 more
doaj
Potassium chloride mixture may maintain hypokalaemia and hypertension
Hypokalaemia can be treated with potassium chloride mixture Some mixtures contain liquorice extract (glycyrrhizin) as a supplement to improve taste Glycyrrhizin can cause pseudohyperaldosteronism and thereby result in hypertension and hypokalaemia We ...
Mandoe, Mette Johannsen +2 more
core +1 more source

