Results 101 to 110 of about 69,001 (309)

Intravenous Magnesium: Prompt use for Asthma in Children Treated in the Emergency Department (IMPACT‐ED), a pilot randomized trial

Academic Emergency Medicine, EarlyView.
Abstract Background Asthma is the most common chronic illness of childhood and a leading cause of hospitalization and health care costs for children. Intravenous magnesium sulfate (IVMg) may help severely ill children avoid hospitalization when added to standard treatment in an emergency department (ED), but this has not been adequately evaluated in a ...
Michael D. Johnson, Bashar S. Shihabuddin, Bradley J. Barney, Mengtao Dai, Toni Harbour, Yeojin Jung, Kameron N. Clinton, Breanna Vance, Madison Reilly, Joseph J. Zorc, for the IMPACT‐ED Collaborators of the Pediatric Emergency Care Applied Research Network (PECARN)   +10 more
wiley   +1 more source

First WNK4-hypokalemia animal model identified by genome-wide association in Burmese cats. [PDF]

PLoS ONE, 2012
Burmese is an old and popular cat breed, however, several health concerns, such as hypokalemia and a craniofacial defect, are prevalent, endangering the general health of the breed.
Barbara Gandolfi, Timothy J Gruffydd-Jones, Richard Malik, Alejandro Cortes, Boyd R Jones, Chris R Helps, Eva M Prinzenberg, George Erhardt, Leslie A Lyons   +8 more
doaj   +1 more source

Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia

Journal of Physiological Sciences, 2019
Hypokalemia, an abnormally low level of potassium (K+), is a electrolyte imbalance that commonly occurs in heart failure patients. Hypokalemia is well known to induce lethal ventricular arrhythmia.
Kensuke Oshita, Yuko Kozasa, Y. Nakagawa, Yoshihiro Kuwabara, K. Kuwahara, Taku Nakagawa, N. Nakashima, T. Hiraki, M. Takano   +8 more
semanticscholar   +1 more source

Versatility of NaCl transport mechanisms in the cortical collecting duct [PDF]

, 2017
Versatility of NaCl transport mechanisms in the cortical collecting duct. Am J Physiol Renal Physiol 313: F1254 –F1263, 2017. First published September 6, 2017; doi:10.1152/ajprenal.00369.2017.—The cortical collecting duct (CCD) forms part of the ...
Crambert, Gilles, Edwards, Aurelie
core   +1 more source

Endocrine Abnormalities and Growth Pattern in Single Large‐Scale Mitochondrial DNA Deletion Syndromes

Acta Paediatrica, EarlyView.
ABSTRACT Aim To assess the prevalence of endocrine disorders and investigate growth patterns in single large‐scale mitochondrial DNA deletion syndromes (SLSMDs). Methods A retrospective study of all children with SLSMD who attended Sheba Medical Center, Israel, from February 2017 to September 2024.
Ayman Daka, Einat Lahav, Omer Bar Yosef, Yoav Bolkier, Yael Levy‐Shraga, Yair Anikster, Elad Jacoby, Noah Gruber   +7 more
wiley   +1 more source

Beta-lactam-associated hypokalemia

Journal of International Medical Research
The aim of this narrative review was to discuss the literature on β-lactam antibiotic-associated hypokalemia, a potentially life-threatening electrolyte disorder.
Muriel-N. Jansen, Wajima Safi, Igor Matyukhin, Friedrich Stasche, Johanna Tennigkeit, Oliver Ritter, Daniel Patschan   +6 more
doaj   +1 more source

A case of hypokalemia-induced bidirectional ventricular tachycardia

Journal of International Medical Research, 2020
Background Bidirectional ventricular tachycardia (BVT) is a rare, but serious, arrhythmia. Hypokalemia is commonly found in clinical practice, but hypokalemia-induced BVT has rarely been reported.
Yanan Xie, Jingzhe Han, Jinming Liu, Jie Hao, Xiuguang Zu, Yuming Hao   +5 more
doaj   +1 more source

Frequency of Hypokalemia, Clinical Implications and Risk Factors in Patients of COVID-19

Pakistan Journal of Medical Research
Objective: To determine the frequency of hypokalemia among COVID-19 patients and assess its impact on the patients management. Study type, settings & duration: It was a cross-sectional study conducted at Mayo Hospital, Lahore from July 2020 to January ...
Sarmad Zahoor, Uzma Malik, Malik Muhammad Atif, Sadia Asif, Aleena Khan, Sumera Hanif, Ibrar Rafique, Muhammad Arif Nadeem Saqib   +7 more
doaj   +4 more sources

A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second-Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma. [PDF]

, 2017
Lessons learnedThe safety profile in the patient groups who received FOLFIRI and simtuzumab did not differ from that in the FOLFIRI and placebo group.The addition of simtuzumab to chemotherapy with FOLFIRI does not improve clinical outcomes in patients ...
Bendell, Johanna, Benson, Al B, Hecht, J Randolph, Verma, Udit, Vyushkov, Dmitry, Yang, Yingsi   +5 more
core   +1 more source

PI3Kδ Inhibitor Parsaclisib in Japanese Patients With Relapsed or Refractory Follicular Lymphoma

Cancer Science, EarlyView.
CITADEL‐213 evaluated the efficacy and safety of parsaclisib (PI3Kδ inhibitor) in Japanese patients with relapsed or refractory follicular lymphoma (R/R FL). The objective response rate was 88.1%, with 23.8% of patients experiencing a complete response and 64.3% experiencing a partial response; treatment‐emergent adverse events led to parsaclisib ...
Noriko Fukuhara, Isao Yoshida, Takuro Ishiguro, Katsuya Fujimoto, Junya Kuroda, Toshiki Uchida, Ryusuke Yamamoto, Yoshiaki Ogawa, Yasushi Hiramatsu, Toshiro Ito, Seiichiro Katagiri, Tomonori Nakazato, Kazumi Suzukawa, Kenzo Kinami, Mi Zhou, Eiju Negoro   +15 more
wiley   +1 more source