Results 101 to 110 of about 57,362 (246)

A pilot study of chemoimmunotherapy in the postconsolidation setting for high‐risk neuroblastoma (ANBL19P1): A report from the Children’s Oncology Group

open access: yesCancer, Volume 132, Issue 2, 15 January 2026.
Abstract Background Survival for patients with high‐risk neuroblastoma remains poor despite current‐era multimodality treatment that includes postconsolidation GD2‐directed immunotherapy. Given the promising responses in patients who receive dinutuximab‐based chemoimmunotherapy in the relapsed setting, the Children’s Oncology Group ANBL19P1 study ...
Ami V. Desai   +13 more
wiley   +1 more source

Regional anesthesia is safe and effective for lower limb orthopedic surgery in patient with renal tubular acidosis and hypokalemia

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2018
Renal tubular acidosis (RTA) with hypokalemia may precipitate acute respiratory failure and potentially fatal arrhythmias like ventricular fibrillation.
Indira Gurajala   +3 more
doaj   +1 more source

Nanoparticle Albumin‐Bound Paclitaxel and Nivolumab for PD‐1 Inhibitor‐Refractory Recurrent or Metastatic Head and Neck Squamous‐Cell Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Introduction Standard therapy for PD‐1 inhibitor‐refractory recurrent or metastatic head and neck squamous‐cell carcinoma (RM‐HNSCC) has limited activity. Drugs bound to albumin selectively target cancer cells with upregulated macropinocytosis, a process driven by constitutively hyper‐activated EGFR/RAS/PIK3CA signaling, which is common in ...
Douglas Adkins   +6 more
wiley   +1 more source

Donepezil‐Induced Severe Anorexia and T‐Wave Inversion in Early‐Onset Alzheimer's Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Donepezil hydrochloride, used to treat Alzheimer's disease, is typically initiated at a low dose and titrated to minimize gastrointestinal side effects. Despite its favorable safety profile, the patient developed severe anorexia, dehydration, and electrocardiographic abnormalities.
Nobuyuki Takahashi   +4 more
wiley   +1 more source

Cerebral Abscess Masquerading as Tuberculoma in a Post‐Renal Transplant Chronic Kidney Disease Patient: A Diagnostic and Therapeutic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Solid organ transplant recipients are at increased risk of acquiring serious infections. We present a case of a 48‐year‐old male with a history of renal transplantation in 2012, chronic kidney disease (CKD) Stage 4, hypertension, uncontrolled diabetes mellitus, and prior tuberculous pleural effusion.
Sakib Abrar   +3 more
wiley   +1 more source

Risk factors analysis of hypokalemia after radical resection of esophageal cancer and establishment of a nomogram risk prediction model

open access: yesFrontiers in Surgery
ObjectiveThis study aimed to explore the risk factors of hypokalemia after radical resection of esophageal cancer (EC) and establish a nomogram risk prediction model to evaluate hypokalemia risk after esophagectomy.
Guanqiang Yan   +7 more
doaj   +1 more source

Phytobezoar—An Unusual Cause of Small Bowel Obstruction in Pediatric Age Group: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Phytobezoars are the most common and well known type of bezoars yet one of the uncommon causes of mechanical obstruction of the small intestine. The reported prevalence rate of phytobezoars is estimated to be 0.4% despite being the 5th most common cause of acute small bowel obstruction.
Aakash Pandit   +3 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams   +7 more
wiley   +1 more source

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