Results 111 to 120 of about 57,362 (246)

A Thorough QT Study to Assess the Effects of Milvexian on Cardiac Repolarization in Healthy Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Milvexian is an oral factor XIa inhibitor in development for prevention of major thromboembolic conditions. This randomized, double‐blind, placebo‐ and positive‐controlled, multiple‐dose, four‐period crossover study assessed the cardic safety of milvexian (including effects on the QT interval of the electrocardiogram), with a supporting in ...
Peter Zannikos, JongHanne Park, Anna Dari, Samiha Takhtoukh, Paul Levesque, Alexei N. Plotnikov, Amitava Mitra, Antoinette Ajavon‐Hartmann, Samira Merali, Juan Jose Perez Ruixo, Navin Goyal   +10 more
wiley   +1 more source

Protection against severe hypokalemia but impaired cardiac repolarization after intense rowing exercise in healthy humans receiving salbutamol [PDF]

, 2018
Tania Atanasovska, Robert L. Smith, Claus Graff, Cao Thach Tran, Jacob Melgaard, Jørgen K. Kanters, Aaron C. Petersen, Antony Tobin, Keld Kjeldsen, Michael J. McKenna   +9 more
openalex   +1 more source

Brugada Syndrome: Presentation and Management of the Atypical Patient in the Emergent Setting [PDF]

, 2020
Introduction: Brugada syndrome is a genetic disorder of the heart’s electrical system that increases a patient’s risk of sudden cardiac death. It is a syndrome most prevalent in Southeast Asians and is found 36 times more commonly in Asians than in ...
Flores, Mario, Nguyen, Alexander, Tano, Vilmogil   +2 more
core  

Neoadjuvant Glucocorticoids Facilitate Resection in Advanced B‐Type Thymomas: A Propensity‐Matched Analysis of Surgical and Survival Outcomes

Thoracic Cancer, Volume 17, Issue 1, January 2026.
Neoadjuvant glucocorticoids facilitated less invasive and more complete resection of advanced B‐type thymomas, leading to reduced operative morbidity and improved progression‐free survival compared to upfront surgery. This study supports a novel downstaging strategy for this challenging disease.
Zhen Yu, Xintao Yu, Jian Cui, Xiang Gao, Xingguo Yang, Ji Ke, Baoxun Zhang, Lei Yu   +7 more
wiley   +1 more source

Real-World Evidence on Levetiracetam-Induced Hypokalemia: An Active Comparator Cohort Study

Drugs - Real World Outcomes
Background Levetiracetam is an anti-seizure medication (ASM) with an established safety profile. However, a potential safety signal of hypokalemia following levetiracetam use was published in the World Health Organization newsletter.
Ohoud Almadani, Raseel Alroba, Almaha Alfakhri, Sumaya Almohareb, Turki Althunian, Adel A. Alrwisan   +5 more
doaj   +1 more source

Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome

Academic Emergency Medicine, Volume 33, Issue 1, January 2026.
ABSTRACT Study Objective Treatment strategies in severe hyponatremia aim at rapid sodium correction to prevent or treat cerebral edema but limit sodium rise to prevent osmotic demyelination syndrome (ODS). The true risk of edema or ODS in ED patients is unknown.
Volker Burst, Ramon Rabii, Julian Peto‐Madew, Thorsten Persigehl, Stefan Haneder, Matthias Johannes Hackl, Christoph Hüser, Moritz Trappe, Sadrija Cukoski, Kathrin Möllenhoff, Victor Suárez   +10 more
wiley   +1 more source

Atrioventricular block, supraventricular tachycardia and grossly ischemic ST-T wave changes; what is the culprit?

JEM Reports
Background: Hypokalemia is a common problem encountered in the emergency department. Severe cases of hypokalemia are associated with increased morbidity and mortality.
Mazen M. Kawji
doaj   +1 more source

Diuretics and Hypokalemia [PDF]

Acta Medica Iranica, 1970
We have studied hypokalemic action of different diuretics in a cooperative study on 28 patients and our results are as follows: I. 28 patients (18 male and 10 female) were the subject of our present study. 2. E. C. G.
Ali A. Handjani, Bijan Nik-Akhtar (Nazari), Hasan Famili   +2 more
doaj  

Torsade de Pointes Induced by Hypokalemia from Imipenem and Piperacillin

Case Reports in Cardiology, 2017
Imipenem-cilastatin and piperacillin-tazobactam are two antibiotics with broad antimicrobial coverage. Besides the many well established adverse effects of these drugs, there have been few case reports of hypokalemia.
Varun Kumar, Sandeep Khosla, Monica Stancu   +2 more
doaj   +1 more source

A 36-Year-Old Woman With an Unexpected Cause of Hypokalemia [PDF]

, 2023
Mohan Rao, P Mirudhubashini Swarup
openalex   +1 more source