Results 131 to 140 of about 69,001 (309)

Risk Factors for Development of Chronic Kidney Disease in Cats [PDF]

, 2016
BACKGROUND: Identification of risk factors for development of chronic kidney disease (CKD) in cats may aid in its earlier detection. HYPOTHESIS/OBJECTIVES: Evaluation of clinical and questionnaire data will identify risk factors for development of ...
Abraham, Adams, Bang, Bartlett, Boor, Brown, Chambrone, Culhaci, D'Agata, DeBowes, Dibartola, Dibartola, Dow, Dow, Erlinger, Finco, Finco, Fisher, Fisher, Fox, Greene, Gunn-Moore, H.M. Syme, Habacher, Haroun, Heiene, Hoek, Hughes, J. Elliott, James, Jepson, Kulldorff, Lappin, Lappin, Lawler, Lindeman, Lulich, N.C. Finch, Obermayr, Pavlica, Poli, Poli, Powe, Rose, Rowe, Taal, Tonelli, Wakeling, White, Whittemore   +49 more
core   +2 more sources

Venetoclax Combined With Chemotherapy in Pediatric and Adolescent/Young Adult Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and although many patients respond to induction therapy, those who relapse or have refractory disease face a poor prognosis. Venetoclax has promising preclinical and clinical activity in ALL.
Andrew E. Place, Seth E. Karol, Christopher J. Forlenza, Todd M. Cooper, Christopher Fraser, Gunnar Cario, Maureen M. O'Brien, Nicolas U. Gerber, Jean‐Pierre Bourquin, Dirk Reinhardt, Jeffrey E. Rubnitz, Joseph T. Opferman, Gauri Sunkersett, Maika Onishi, Diana R. Dunshee, Xin Chen, Kristina Unnebrink, Deeksha Vishwamitra, Fengjiao Dunbar, Mohamed Badawi, Jeremy A. Ross, Mignon L. Loh   +21 more
wiley   +1 more source

Profound hypokalemia associated with severe diabetic ketoacidosis

Pediatric Diabetes, 2016
Hypokalemia is common during the treatment of diabetic ketoacidosis (DKA); however, severe hypokalemia at presentation prior to insulin treatment is exceedingly uncommon.
S. Davis, A. Maddux, G. Alonso, Carol Okada, Peter M. Mourani, D. Maahs   +5 more
semanticscholar   +1 more source

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. [PDF]

, 1999
A novel potassium channel gene has been cloned, characterized, and associated with cardiac arrhythmia. The gene encodes MinK-related peptide 1 (MiRP1), a small integral membrane subunit that assembles with HERG, a pore-forming protein, to alter its ...
Antzelevitch, Blumenthal, Busch, Busch, Carmeliet, Carmeliet, Chen, Curran, Daleau, Drici, Duggal, Federico Sesti, Geoffrey W Abbott, Goldstein, Ho, Ho, Howarth, Igor Splawski, Kaczmarek, Katherine W Timothy, Lee, Lees-Miller, Liu, London, Makkar, Marianne E Buck, Mark T Keating, McDonald, Michael H Lehmann, Roden, Roden, Sanguinetti, Sanguinetti, Sanguinetti, Sanguinetti, Scamps, Schulze-Bahr, Sesti, Shibasaki, Smith, Snyders, Spector, Spector, Splawski, Splawski, Steve A.N Goldstein, Tai, Tai, Takumi, Takumi, Trudeau, Tyson, Veldkamp, Vetter, Wang, Wang, Wang, Wang, Wollnik, Yang, Yang, Yang, Yang, Zhou, Zou   +64 more
core   +1 more source

Frequency of abnormal results in screening laboratory tests and associated interventions in emergency psychiatric services

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.
Severe psychiatric patients often have abnormal laboratory test findings. Most abnormalities are attributed to agitation or are clinically insignificant, and interventions are limited. Medical intervention was often promoted by the patient's medical history.
Shotaro Fujiwara, Takuto Ishida, Masafumi Mizuno   +2 more
wiley   +1 more source

Real-World Evidence on Levetiracetam-Induced Hypokalemia: An Active Comparator Cohort Study

Drugs - Real World Outcomes
Background Levetiracetam is an anti-seizure medication (ASM) with an established safety profile. However, a potential safety signal of hypokalemia following levetiracetam use was published in the World Health Organization newsletter.
Ohoud Almadani, Raseel Alroba, Almaha Alfakhri, Sumaya Almohareb, Turki Althunian, Adel A. Alrwisan   +5 more
doaj   +1 more source

Psychotropic Polypharmacy and QT Prolonging Medications in Hospitalized Patients

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT It is common for patients with mental illnesses to be prescribed multiple psychotropic medications to effectively manage their conditions. Psychotropic polypharmacy has been shown to potentiate and increase the risks of several adverse effects, including QT prolongation. This study aimed to investigate the prescribing trends of and differences
Joel Moore, Isabella Singh, Ruby Tszwai Au, Genevieve Gabb, Joanne Eng‐Frost, Elizabeth Hotham, Sepehr Shakib, Vijayaprakash Suppiah   +7 more
wiley   +1 more source

Systemic EP4 receptor agonist and Arginase‐1 therapy in a murine model of chronic asthma and influenza virus‐induced asthma exacerbation

British Journal of Pharmacology, Volume 182, Issue 12, Page 2803-2820, June 2025.
Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange, Tobias Brunn, Charlotte Vetter, Konstantin Bloch, Nora Vedder, Chiel van Geffen, Philipp Gercke, Saeed Kolahian   +7 more
wiley   +1 more source

Association between hypokalemia and small bowel capsule endoscopy completion rates in patients in South China: A prospective single-center study

The Saudi Journal of Gastroenterology, 2019
Background/Aims: Approximately 20–30% of small bowel capsule endoscopies (SBCEs) do not reach the cecum at the completion of the examination. We aimed to determine whether hypokalemia influences the completion rate and small bowel transit time (SBTT) of ...
Huo-Ye Gan, Tie-Li Peng, Kai-Hua Su, Lin-Li Zhao, Li-Qin Jian, Rong-Jiao Yang, Han-Xian Zhang, Ru-Yin Pan   +7 more
doaj   +1 more source

Anlotinib in combination with docetaxel for advanced nonsmall cell lung cancer after failure of platinum‐based treatment: A phase 1/2 trial

Cancer, Volume 131, Issue 10, 15 May 2025.
Abstract Background The combination of anlotinib with chemotherapy has demonstrated encouraging efficacy in the treatment of nonsmall cell lung cancer (NSCLC). The objective of this phase 1/2 trial was to establish the maximum tolerated dose of anlotinib in combination with docetaxel and to assess the efficacy and safety of this regimen in patients ...
Jiawei Shou, Jun Chen, Qunyi Guo, Wei Hong, Yonghui Wang, Chuangzhou Rao, Liqin Lu, Xinmei Yang, Dan Zhu, Fen Lan, Yong Fang, Hongming Pan   +11 more
wiley   +1 more source