Results 41 to 50 of about 34,454 (220)

Placebo‐Controlled, Randomized Double‐Blind N‐Of‐1 Trial to Study Safety and Potential Efficacy of TJ‐68 for Improving Muscle Cramps in Patients With Amyotrophic Lateral Sclerosis: A Pilot Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Muscle cramps are a common symptom in amyotrophic lateral sclerosis (ALS). Ameliorating muscle cramps may improve quality of life in devastating diseases like ALS. A traditional Japanese medicine (Kampo, TJ‐68) is widely prescribed in Japan for muscle cramps. However, it is not available in the USA.
Hiroshi Mitsumoto, Ken Cheung, Björn Oskarsson, Grace E. Jang, Howard F. Andrews, Stephen Johnson, Jaimin S. Shah, Joseph Americo Fernandes Jr, Jinsy A. Andrews, Maya Rao, Martin McElhiney   +10 more
wiley   +1 more source

Micronutrient deficiencies after pancreatico‐duodenectomy: A narrative review of the literature and recommendations for clinical practice

Nutrition in Clinical Practice, EarlyView.
Abstract Micronutrient uptake is impaired after pancreatico‐duodenectomy (PD) because of malabsorption, reduced absorptive capacity, and poor oral intake. Biochemical depletion is reported in cohort studies, but deficiency states are predominantly reported in case reports, making it difficult to assess occurrence rates.
Mary E. Phillips, Callum Livingstone, Adam E. Frampton, Kathryn H. Hart   +3 more
wiley   +1 more source

Intravenous Magnesium: Prompt use for Asthma in Children Treated in the Emergency Department (IMPACT‐ED), a pilot randomized trial

Academic Emergency Medicine, EarlyView.
Abstract Background Asthma is the most common chronic illness of childhood and a leading cause of hospitalization and health care costs for children. Intravenous magnesium sulfate (IVMg) may help severely ill children avoid hospitalization when added to standard treatment in an emergency department (ED), but this has not been adequately evaluated in a ...
Michael D. Johnson, Bashar S. Shihabuddin, Bradley J. Barney, Mengtao Dai, Toni Harbour, Yeojin Jung, Kameron N. Clinton, Breanna Vance, Madison Reilly, Joseph J. Zorc, for the IMPACT‐ED Collaborators of the Pediatric Emergency Care Applied Research Network (PECARN)   +10 more
wiley   +1 more source

Gitelman Syndrome in a Case of Diabetic Kidney Disease: A Diagnostic and Therapeutic Dilemma [PDF]

Journal of Clinical and Diagnostic Research, 2018
Gitelman syndrome is an autosomal recessive disorder that usually presents with hypokalemia, hypomagnesemia, hypocalciuria and normal blood pressure. In contrast to Bartter syndrome it presents in late adulthood.
Vaibhav Seth, Niladri Sarkar, Somnath Mandal, Subhasis Neogi, Shambaditya Das   +4 more
doaj   +1 more source

Evaluation of exposure‐response‐safety relationship of model‐informed low‐dose 500 mg abiraterone acetate in prostate cancer patients

Cancer Communications, EarlyView.
Edmund Chiong, Ziteng Wang, Eleanor Jing Yi Cheong, Yi Chen Yao, Sin Mun Tham, Revathi Periaswami, Poh Choo Toh, Ziting Wang, Qing Hui Wu, Woon Chau Tsang, Arshvin Kesavan, Alvin Seng Cheong Wong, Patrick Thomas Wong, Felicia Lim, Shuaibing Liu, Eric Chun Yong Chan   +15 more
wiley   +1 more source

PI3Kδ Inhibitor Parsaclisib in Japanese Patients With Relapsed or Refractory Follicular Lymphoma

Cancer Science, EarlyView.
CITADEL‐213 evaluated the efficacy and safety of parsaclisib (PI3Kδ inhibitor) in Japanese patients with relapsed or refractory follicular lymphoma (R/R FL). The objective response rate was 88.1%, with 23.8% of patients experiencing a complete response and 64.3% experiencing a partial response; treatment‐emergent adverse events led to parsaclisib ...
Noriko Fukuhara, Isao Yoshida, Takuro Ishiguro, Katsuya Fujimoto, Junya Kuroda, Toshiki Uchida, Ryusuke Yamamoto, Yoshiaki Ogawa, Yasushi Hiramatsu, Toshiro Ito, Seiichiro Katagiri, Tomonori Nakazato, Kazumi Suzukawa, Kenzo Kinami, Mi Zhou, Eiju Negoro   +15 more
wiley   +1 more source

Implications for medication safety and adherence in dermato‐oncology: The AMBORA care program for oral antitumor therapeutics

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Dermatological oral antitumor therapeutics (OAT) are often interaction‐prone and used in complex regimens. The pharmacological/pharmaceutical care program of the randomized AMBORA trial significantly improved medication safety with various OAT; however, dermato‐oncological patients were not included.
Lisa Cuba, Frank Dörje, Rafaela Kramer, Pauline Dürr, Michael Erdmann, Martin F. Fromm, Carola Berking, Katja Gessner   +7 more
wiley   +1 more source

Use of Extracorporeal Therapies to Treat Severe Caffeine Poisoning

Hemodialysis International, EarlyView.
ABSTRACT Introduction Reflecting on recent reports suggesting the efficacy of extracorporeal blood purification, including hemodialysis, for severe caffeine poisoning, we conducted a retrospective 6‐year follow‐up study on acute caffeine poisoning in Japan particularly focusing on extracorporeal blood purification.
Saeko Kohara, Yoshito Kamijo, Michiko Takai, Ryoko Kyan, Eiju Hasegawa, Takuya Shimane   +5 more
wiley   +1 more source

Frequency of Hypokalemia, Clinical Implications and Risk Factors in Patients of COVID-19

Pakistan Journal of Medical Research
Objective: To determine the frequency of hypokalemia among COVID-19 patients and assess its impact on the patients management. Study type, settings & duration: It was a cross-sectional study conducted at Mayo Hospital, Lahore from July 2020 to January ...
Sarmad Zahoor, Uzma Malik, Malik Muhammad Atif, Sadia Asif, Aleena Khan, Sumera Hanif, Ibrar Rafique, Muhammad Arif Nadeem Saqib   +7 more
doaj   +4 more sources

Beta-lactam-associated hypokalemia

Journal of International Medical Research
The aim of this narrative review was to discuss the literature on β-lactam antibiotic-associated hypokalemia, a potentially life-threatening electrolyte disorder.
Muriel-N. Jansen, Wajima Safi, Igor Matyukhin, Friedrich Stasche, Johanna Tennigkeit, Oliver Ritter, Daniel Patschan   +6 more
doaj   +1 more source