Results 21 to 30 of about 23,658 (224)

A Rare Cause of Seizures: Hypomagnesemia Type 1

Revista Portuguesa de Nefrologia e Hipertensão, 2023
Hypomagnesemia type I is a rare autosomal recessive disorder characterized by severe hypomagnesemia, often accompanied by hypocalcemia. This disease is caused by mutations in the TRPM6 gene (which encodes the respective channel), leading to reduced ...
Inês Gameiro, Catarina Pinto Silva, Marta Machado, Carolina Cordinhã, Carmen do Carmo, Clara Gomes   +5 more
doaj   +1 more source

Transient receptor potential melastatin 7 cation channel kinase new player in angiotensin II–induced hypertension [PDF]

, 2016
Transient receptor potential melastatin 7 (TRPM7) is a bifunctional protein comprising a magnesium (Mg2+)/cation channel and a kinase domain. We previously demonstrated that vasoactive agents regulate vascular TRPM7.
Antunes, Tayze T., Callera, Glaucia E., He, Ying, Ryazanov, Alexey G., Ryazanov, Lillia V., Shrier, Alvin, Stewart, Duncan J., Touyz, Rhian, Yogi, Alvaro, Zhai, Alexander   +9 more
core   +1 more source

Lung squamous cell carcinoma with severe hypomagnesemia due to cisplatin plus gemcitabine in combination with necitumumab therapy: A case report

Thoracic Cancer, 2021
A 72‐year‐old man, diagnosed with advanced lung squamous cell carcinoma, was administered of cisplatin plus gemcitabine with necitumumab, a human monoclonal antibody that binds to the epidermal growth factor receptor (EGFR), as a sixth‐line treatment ...
Akira Nakao, Hiroyuki Inoue, Yusuke Osaki, Ryosuke Hirano, Taishi Harada, Takashi Aoyama, Fumiyasu Igata, Masaki Fujita   +7 more
doaj   +1 more source

Dual EGFR inhibition in combination with anti-VEGF treatment: a phase I clinical trial in non-small cell lung cancer. [PDF]

, 2013
BackgroundPreclinical data indicate EGFR signals through both kinase-dependent and independent pathways and that combining a small-molecule EGFR inhibitor, EGFR antibody, and/or anti-angiogenic agent is synergistic in animal models.MethodsWe conducted a ...
Bastida, Christel, Falchook, Gerald S, Fu, Siqing, Hong, David S, Jiang, Yunfang, Kurzrock, Razelle, Morgan-Linnell, Sonia K, Naing, Aung, Piha-Paul, Sarina A, Tsimberidou, Apostolia M, Wheler, Jennifer J, Zinner, Ralph   +11 more
core   +2 more sources

Acute Hepatic Porphyrias: Review and Recent Progress. [PDF]

, 2019
The acute hepatic porphyrias (AHPs) are a group of four inherited diseases of heme biosynthesis that present with episodic, acute neurovisceral symptoms.
Andant, Anderson, Andersson, Badawy, Balwani, Bissell, Bissell, Bloomer, Bonkovsky, Bonkovsky, Bonkovsky, Bonkovsky, Bonkowsky, Bonkowsky, Bonkowsky, Bylesjo, Chen, D’Avola, Ferrer, Glueck, Handschin, Jeans, Lambrecht, Lane, Marsden, McGuire, Pallet, Sardh, Sardh, Shen, Singal, Stein, Stewart, Tchernitchko, Wahlin, Watson, Watson, Willandt, Wu, Yarra, Yasuda   +40 more
core   +1 more source

Case Reports : Two patients with parathyroid hormone suppression caused by proton pump inhibitors [PDF]

, 2017
Hypocalcemia can be associated with coexisting hypomagnesemia, which induces hypoparathyroidism as well as resistance to parathyroid hormone (PTH). Here, we present two patients with severe hypomagnesemia and associated hypocalcemia, caused by proton ...
Naqvi, Ali
core   +1 more source

Proton pump inhibitors and hospitalization with hypomagnesemia: a population-based case-control study.

PLoS Medicine, 2014
BackgroundSome evidence suggests that proton pump inhibitors (PPIs) are an under-appreciated risk factor for hypomagnesemia. Whether hospitalization with hypomagnesemia is associated with use of PPIs is unknown.Methods and findingsWe conducted a ...
Jonathan Zipursky, Erin M Macdonald, Simon Hollands, Tara Gomes, Muhammad M Mamdani, J Michael Paterson, Nina Lathia, David N Juurlink   +7 more
doaj   +1 more source

Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease [PDF]

, 2018
BACKGROUND: Hypomagnesemia is associated with increased mortality and renal function decline in humans with chronic kidney disease (CKD). Magnesium is furthermore inversely associated with fibroblast growth factor 23 (FGF23), an important prognostic ...
Andrukhova, Andrukhova, Andrukhova, Angelen, Atarashi, Baaij, Barber, Barber, Barber, Barnes, Barr, Bateman, Blaine, Boyd, Bressendorff, Chakrabarti, Chakrabarti, Cheng, Covic, Cunha, Diaz-Tocados, DiBartola, Elin, Elliott, Geddes, Geddes, Geddes, Geddes, Geiger, Ichihara, Iguchi, Isakova, Ishimura, Ishimura, Jahnen-Dechent, Jensen, Jepson, Joffres, Joosten, Kanbay, Kass, King, Kisters, Laecke, Laecke, Laecke, Lawson, Louvet, Lulich, Ma, Matsuzaki, Matsuzaki, McLeland, Meema, Moe, Moe, Mutsert, Nakayama, Navarro-Gonzalez, Norris, Pearson, Plantinga, Resnick, Ross, Ross, Sakaguchi, Sakaguchi, Sakaguchi, Sakaguchi, Sakaguchi, Sakaguchi, Salem, Satake, Shimada, Slatopolsky, Sontia, Toll, Touyz, Williams, Wooldridge, Yogi, Zhang   +81 more
core   +2 more sources

14 Relation of Low Serum Magnesium Level with Type-2 Diabetes Mellitus in Eastern India

JK Science, 2022
Background: Odisha, a state in eastern India is swiftly becoming one among the diabetes hotspots in the country. Magnesium deficiency is implicated in poor glycemic status and various complications of diabetes.
Subhash Chandra, Sahu Sarada Prasad, Swaim Rakesh Keshari, Ratan Kireet   +3 more
doaj  

Hypomagnesemia in beef cattle [PDF]

Pesquisa Veterinária Brasileira, 2021
: Hypomagnesemia is a major cause of death in grazing beef cows in countries of the Southern Hemisphere such as Argentina, Australia and New Zealand. Here we review the literature on hypomagnesemia in beef cattle and describe an outbreak in Uruguay.
Benjamín Doncel, Juan D. Puentes, Rubén D. Caffarena, Franklin Riet-Correa, Ricardo A. Costa, Federico Giannitti   +5 more
doaj   +1 more source