Results 51 to 60 of about 23,658 (224)

Proton-pump inhibitor use is associated with low serum magnesium concentrations [PDF]

, 2017
Although case reports link proton-pump inhibitor (PPI) use and hypomagnesemia, no large-scale studies have been conducted. Here we examined the serum magnesium concentration and the likelihood of hypomagnesemia ( < 1.6 mg/dl) with a history of PPI or ...
Celi, Leo Anthony G., Danziger, John, Howell, Michael D., Lee, Joonwu, Lehman, Li-Wei, Mark, Roger G, Mukamal, Kenneth J., Scott, Daniel, William, Jeffrey H.   +8 more
core   +1 more source

Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors

Gastroenterology Research and Practice, 2015
In 2006, hypomagnesemia was first described as a complication of proton-pump inhibitors. To address this issue, we systematically reviewed the literature.
Simone Janett, Pietro Camozzi, Gabriëlla G. A. M. Peeters, Sebastiano A. G. Lava, Giacomo D. Simonetti, Barbara Goeggel Simonetti, Mario G. Bianchetti, Gregorio P. Milani   +7 more
doaj   +1 more source

Dietary management of normoalbuminaemic canine chronic enteropathies

Journal of Small Animal Practice, EarlyView.
Dietary management represents the cornerstone of treatment for chronic enteropathy in dogs, with approximately 50% of cases in referral practice responding to dietary intervention alone. Success rates improve significantly when multiple systematic diet trials are implemented.
A. Kathrani, K. Allenspach, D. Dito, J. Hernandez, S. Unterer, M. Vecchio, C. Webb, M. K. Tolbert   +7 more
wiley   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia. [PDF]

, 2016
Acute myeloid leukemia (AML) cells meet the higher energy, metabolic, and signaling demands of the cell by increasing mitochondrial biogenesis and mitochondrial protein translation.
Brandwein, Joseph, Douer, Dan, Gronda, Marcela, Gupta, Vikas, Hurren, Rose, Jitkova, Yulia, Kambhampati, Suman, Minden, Mark D, Reed, Gregory A, Schiller, Gary J, Schimmer, Aaron D, Schuh, Andre C, Shamas-Din, Aisha, Tallman, Martin S, Yee, Karen W   +14 more
core   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1385-1396, May 2026.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

Hypomagnesemia: exploring its multifaceted health impacts and associations with blood pressure regulation and metabolic syndrome

Diabetology & Metabolic Syndrome
This article provides a comprehensive and in-depth exploration of the multifaceted effects of Hypomagnesemia on human health, with a specific focus on its intricate associations with mechanisms regulating blood pressure and metabolic syndrome.
Wenlong Wu, Ming Gong, Pan Liu, Huiying Yu, Xue Gao, Xin Zhao   +5 more
doaj   +1 more source

Dopamine‐Induced Seizure in a Heart Failure Patient: A Case Report and Review of Neurotoxic Implications

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In heart failure patients, dopamine therapy, particularly at higher doses, may induce seizures due to its impact on cerebral blood flow and exacerbation of underlying hypoxemia and electrolyte imbalances. Close monitoring and cautious use of dopamine, with consideration of alternative inotropic agents like dobutamine, are essential to mitigate
Chuanwei Zhao, Yane Yang, Mu Lin, Zeyao Hu, Linhuan Huang   +4 more
wiley   +1 more source

The relationship between hypomagnesemia and ICU mortality in severe hemorrhagic stroke patients: an observational multicentre study on eICU database

BMC Cardiovascular Disorders
Background Hemorrhagic stroke is a potentially fatal condition with high mortality and morbidity. However, there is a lack of evidence for this relationship in critically ill patients with hemorrhagic stroke.
Xinzhao Jiang, Faliang Gao, Zongjie Shi, Fang Liu, Wenyan Zhao, Guihong Gong   +5 more
doaj   +1 more source

Improved bilirubin reduction with therapeutic plasma exchange and haemoperfusion in a dog with immune‐mediated haemolytic anaemia

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 6‐year‐old spayed female Golden Retriever mix was diagnosed with immune‐mediated haemolytic anaemia. Initial treatments included immunosuppression and blood transfusions. With acute mentation decline and rapid increase in serum bilirubin, therapeutic plasma exchange (TPE) was initiated.
Natasha S. Yeh, Kay Drake, Michael T. Kato   +2 more
wiley   +1 more source