Results 81 to 90 of about 37,277 (211)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, Volume 30, Issue 4, Page 460-470, August 2026.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Isolated hypoaldosteronism is a cause of hypovolemic but not euvolemic hyponatremia

Endocrine Connections
Introduction: Hypoaldosteronism is characterized by hyperkalemia, and/or hypovolemic hyponatremia (HH), often accompanied by metabolic acidosis. HH is typical of hypoaldosteronism, whereas euvolemic hyponatremia (EH) is not.
Jorge Gabriel Ruiz-Sánchez, Alfonso Luis Calle-Pascual, Miguel Ángel Rubio-Herrera, María Paz De Miguel Novoa, Emilia Gómez-Hoyos, Isabelle Runkle   +5 more
doaj   +1 more source

Delay in Diagnosis of Addison's Disease: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Graphic highlighting the timeline of ED visits and admissions for the case patient. ABSTRACT Primary adrenal insufficiency is a rare disorder prone to delay in diagnosis after initial presentation. Multiple factors including a wide range of presentations, slow onset of symptoms, and other human factors may be contributing to challenges with the ...
Ishita Bhattacharya, Lisle Blackbourn, Manajyoti Yadav   +2 more
wiley   +1 more source

Hand Lesions as a Diagnostic Clue in Unexplained SIADH

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Chilblain‐like hand lesions in a patient with otherwise unexplained SIADH prompted evaluation for autoimmune connective tissue disease. (A) Hand lesions before treatment. (B) Marked improvement after topical difluprednate therapy. (C) Skin biopsy showing basal liquefaction/interface change with superficial perivascular lymphocytic infiltration.
Nobuko Watanabe, Takuya Omura, Takahiro Kamihara, Taiki Sugimoto, Jun Matsumoto, Tomomi Omura, Masaki Hasegawa, Mariko Shimono, Zenzo Isogai   +8 more
wiley   +1 more source

Ciprofloxacin‐Induced Near‐Total Toxic Epidermal Necrolysis Complicated by Upper Gastrointestinal Bleeding: A Case Report With ALDEN‐Based Causality Assessment

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Toxic epidermal necrolysis (TEN) is a rare but life‐threatening mucocutaneous adverse drug reaction characterized by widespread epidermal necrosis and detachment with significant mucosal involvement. We report a case of near total (80%–90%) body surface area TEN in a previously healthy 30‐year‐old man that developed approximately 5 days after ...
Amanuel D. Wakoya, Alemu B. Mesekere, Seid A. abdullahi, Misale B. Tesfaye, Zeynu H. Endris, Zelalem G. Demissie, Tibebu G. Haile   +6 more
wiley   +1 more source

Atorvastatin‐Associated Severe Bradyarrhythmia Following Multiorgan Dysfunction: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Statins are the primary treatment for hypercholesterolemia and a cornerstone of atherosclerotic cardiovascular disease prevention. Although generally safe, serious adverse effects may occur in selected patients, particularly when statins are used at high doses or without medical supervision.
Xiao‐Qing Kou, Yan‐Zhen Wang, Yi‐Rong Gan, Yun‐Long Zhang, Shu‐Yun He, Zheng Zhang   +5 more
wiley   +1 more source

A Rare Constellation of Peripartum Cardiomyopathy Manifesting With Multiple Thromboembolic Phenomena in a 15‐Year‐Old

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 15‐year‐old postpartum primipara presented at 19 days with aphasia, right hemiparesis, chest pain, and dyspnea. Diagnostics confirmed concurrent cardioembolic stroke and pulmonary embolism secondary to peripartum cardiomyopathy (ejection fraction 29%).
Reuben E. Mkama, Bibiana Kazaura, Theresia E. Lutufyo, Baraka E. Mrisho, Hery O. Kimwela, Marco E. Nyakasalule, Ronald M. Costantini, Eliya Msemwa, Florence Malamso, George Assenga, Julius Kinyange, Josephine R. Laswai, Fabian M. Kamana, Godfery Malangwa, David S. Mazengo, Raymond Leiya, Andrea S. Hondo, Masuma Gulamhussein, Happiness J. Mathew, Paul P. Mwasapi, Phillip S. Muhochi, Hakolo L. Mgaya, Moa E. Kalunga, Brendan P. Shayo, Amani E. Senso, Leonia N. Ndakamaze, Tuzo Lyuu, Anna A. Sanga, Rosemary P. Minja, Deusdedit Ndilanha, Emmanuel J. Magandi, Nkulikiye Kanani, Anthony J. Gyunda, Immaculate R. Goima, Justus L. Ishengoma, Janet L. Mtenga, Flora N. Ndobho, Kigocha L. Okengo, Paschal N. Kulwijila, Pius C. Njingo   +39 more
wiley   +1 more source

Open‐Label, Balanced, Randomized, Single‐Dose, Three‐Treatment, Three‐Sequence, Three‐Period, Three‐Way Crossover Oral Bioequivalence Study of Desmopressin Acetate Oral Solution

Clinical Pharmacology in Drug Development, Volume 15, Issue 8, August 2026.
ABSTRACT Desmopressin is first‐line therapy for central diabetes insipidus, also known as arginine vasopressin deficiency, but presents dosing challenges due to its narrow therapeutic index. This open‐label, randomized, three‐way crossover study evaluated the bioequivalence of a new desmopressin acetate oral solution (50 mcg/mL) compared to ...
Adam Christensen, Axay Parth, Mansi Kotak, Danka Radosavjevic, Catherine Gorman Moore, Byung‐Woun Seo   +5 more
wiley   +1 more source

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 412-419, August 2026.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Frailty‐associated outcomes in geriatric emergency medicine ward patients: A retrospective cohort study informing program development

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background Frail elderly patients require more interventions, and longer hospitalizations due to their complex health needs. The Emergency Medicine Ward (EMW) aims to provide acute care for patients with low‐acuity medical issues, often using a multidisciplinary approach for holistic care and discharge.
Tsz Kiu Chan, Man Ting Lau, Ka In Chan, Yuen Wa Ip, Wing Yuk Chan, Sze Yan Pui, Ying Ying Lam, Shing Ko, Oi Fung Wong, Sau Lai Chan, Candy Leung, Tsz Wah Patrick So, Po Fan Paul Chui, Wai Bik Geraldine Ng   +13 more
wiley   +1 more source