Results 101 to 110 of about 22,989 (220)

Risk of Head and Neck Cancer in Former Smokers by Subsite: A Multicenter Analysis From the INHANCE Consortium

International Journal of Cancer, Volume 159, Issue 5, Page 1204-1217, 1 September 2026.
Tobacco use and alcohol consumption are primary risk factors for head and neck squamous cell carcinoma, with combined use occurring in three‐quarters of cases. This large international study of former smokers shows that the risk reduction effect of smoking cessation occurs more slowly for laryngeal cancer than for other head and neck cancer subsites ...
Matheus de Abreu, Luiz Paulo Kowalski, Rossana Mendoza López, Christine Barul, Loredana Radoi, Ettore Bidoli, Jerry Polesel, Victor Wunsch‐Filho, Andrew F. Olshan, Jose Zevallos, Eva Negri, Valeria Edefonti, Beata Świątkowska, Dana Mates, Eleonora Fabianova, Jolanta Lissowska, Oxana Shangina, Paul Brennan, Tamas Pandics, Luigino Dal Maso, Hal Morgenstern, Zuo‐Feng Zhang, Karl Kelsey, Michael McClean, Carlo La Vecchia, Werner Garavello, Chu Chen, Stephen M. Schwartz, Heribert Ramroth, Volker Winkler, Gabriella Cadoni, Stefania Boccia, Hermann Brenner, Gypsyamber D'Souza, Neil Gross, Joshua Muscat, Mahsa Abedini, Michele Sassano, Paolo Boffetta, Mia Hashibe, Yuan‐Chin Amy Lee, Maria Paula Curado   +41 more
wiley   +1 more source

Accelerated Biological Aging Increases the Risk of Head and Neck Cancer: Insights From Genetic Instruments of Epigenetic Clocks

Molecular Carcinogenesis, Volume 65, Issue 9, Page 1105-1113, September 2026.
ABSTRACT Epigenetic clocks are robust biomarkers of biological aging and have been associated with cancer susceptibility. However, the relationship between genetically predicted epigenetic age acceleration and head and neck cancer risk remains unclear. Using a large case‐control study of 2189 head and neck squamous cell carcinoma (HNSCC) cases and 2189
Jiaqi Wang, Jie Deng, Yifan Xu, Chia‐Wen Tsai, Wen‐Shin Chang, Yang Deng, Maosheng Huang, Da‐Tian Bau, Guojun Li, Jian Gu   +9 more
wiley   +1 more source

Brain metastasis in head and neck cancer: an analysis of 201 cases

Frontiers in Oncology
ObjectiveTo elucidate the clinicopathological characteristics and survival trajectories of patients with head and neck squamous cell carcinoma (HNSCC) who developed brain metastasis (BM).MethodsThis retrospective analysis enrolled patients diagnosed with
Junhui Yuan, Junhui Yuan, Hao Li, Wei Du, Dairong Cao, Dairong Cao, Dairong Cao   +6 more
doaj   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, Volume 13, Issue 46, 17 August 2026.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

An Empty Stomach or False Reassurance? Aspiration Pneumonitis Despite Prolonged Preoperative Fasting in a Low‐Risk Patient

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A healthy 38 year‐old male developed severe bronchospasm and aspiration pneumonitis during anesthesia induction despite 15‐h preoperative fasting. Imaging revealed bilateral pulmonary consolidations and gastric distension. This case visually highlights that prolonged fasting paradoxically fails to guarantee gastric emptiness, emphasizing the ...
Tommaso Foggi Viligiardi, Giulia Borsotti, Gabriele Baldini, Chiara Adembri   +3 more
wiley   +1 more source

Endoscopic Findings of Mucosal Pemphigus Vulgaris: Clinical Correlation and Diagnostic Value

Dermatology Practical & Conceptual
Background: Pemphigus vulgaris (PV) is an autoimmune bullous disease that usually starts on the oral mucosa but it can affect all mucosal surfaces.
Zeynep Karaca Ural, Merve Hatun Erkayman, Zeynep Utlu, Handan Bilen , Özgür Yörük   +4 more
doaj   +1 more source

Exploring hsa_circ_0100833 as a Potential Biomarker in Oral Squamous Cell Carcinoma: Bioinformatics and Experimental Insights

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objectives Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with few reliable early diagnostic markers. Bioinformatic screening identified hsa_circ_0100833 as a differentially expressed circRNA in OSCC. Its potential significance in OSCC was then examined experimentally.
Behnaz Raei, Yousef Seyedena, Mehrdad Hashemi, Nazanin Hosseinkhan, Mojgan Alaeddini   +4 more
wiley   +1 more source

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, Volume 48, Issue 8, Page 2048-2056, August 2026.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

Disease Site‐Specific Outcomes in p16‐Positive Non‐Oropharyngeal Mucosal Head and Neck Cancer

Head &Neck, Volume 48, Issue 8, Page 2156-2169, August 2026.
ABSTRACT Objectives To report disease‐free survival (DFS) in p16‐positive non‐oropharyngeal head‐and‐neck squamous‐cell carcinoma (HNSCC). Methods Curatively‐treated non‐oropharyngeal HNSCC (2009–2021) were reviewed. DFS was compared among p16‐positive, p16‐negative, and p16‐untested cases for the overall cohort and by disease site.
Revadhi C. Chelvarajah, Lessandra Y. S. Chee, Jie Su, Brian O'Sullivan, Christopher M. K. L. Yao, Enrique Sanz‐Garcia, Stephen M. Smith, Ilan Weinreb, Scott Bratman, B. C. John Cho, Ezra Hahn, Andrew Hope, Ali Hosni, John Kim, Andrew McPartlin, Nauman Malik, Chiaojung Jillian Tsai, John de Almeida, Anna Spreafico, Li Tong, Shao Hui Huang, John N Waldron   +21 more
wiley   +1 more source

Toward a Typology of Patients With Head and Neck Cancer: Biopsychosocial Profiles Predicting Longitudinal Quality of Life

Head &Neck, Volume 48, Issue 8, Page 2120-2134, August 2026.
ABSTRACT Background Quality of life (QoL) in head and neck cancer (HNC) is influenced by complex biopsychosocial factors, yet few longitudinal studies have examined these relationships immediately post‐treatment. Methods In this prospective study, 232 patients newly diagnosed with primary HNC completed psychometric assessments, clinical interviews, and
Haley Deamond, Cyril Devault‐Tousignant, Jacob Lang, Christopher Lo, Jennifer Silver, Nader Sadeghi, Zeev Rosberger, Saul Frenkiel, Michael Hier, Anthony Zeitouni, Karen Kost, Alex Mlynarek, Keith Richardson, Gabrielle Chartier, Marco Mascarella, Khalil Sultanem, Georges Shenouda, Fabio Cury, Melissa Henry   +18 more
wiley   +1 more source