Results 101 to 110 of about 7,727 (215)

Targeting Fibroblast Growth Factor 23 Signaling with Antibodies and Inhibitors, Is There a Rationale?

Frontiers in Endocrinology, 2018
Fibroblast growth factor 23 (FGF23) is a phosphotropic hormone mainly produced by bone. FGF23 reduces serum phosphate by suppressing intestinal phosphate absorption through reducing 1,25-dihydroxyvitamin D and proximal tubular phosphate reabsorption ...
Seiji Fukumoto
doaj   +1 more source

SAT-373 A Case of X Linked Hypophosphatemic Rickets Due to DE Novo Phex Gene Mutation [PDF]

, 2020
Ahmed Badran, Renee Bargman
openalex   +1 more source

NaPi-IIa interacting proteins and regulation of renal reabsorption of phosphate [PDF]

, 2018
Control of phosphate (Pi) homeostasis is essential for many biologic functions and inappropriate low levels of Pi in plasma have been suggested to associate with several pathological states, including renal stone formation and stone recurrence.
Biber, Jürg, Capuano, Paola, Déliot, Nadine, Gisler, Serge, Hernando, Nati, Murer, Heini, Reining, Sonja   +6 more
core  

Intact fibroblast growth factor 23 and fragments in plasma from Gambian children [PDF]

, 2012
SUMMARY: Fibroblast growth factor 23 (FGF23) is grossly elevated in Gambian children with rickets and, at a lower prevalence, in those without bone deformities.
A. Prentice, S. F. A. Bruggraber, V. Braithwaite   +2 more
core   +1 more source

Analysis of Thisbe and Pyramus functional domains reveals evidence for cleavage of Drosophila FGFs [PDF]

, 2010
Background: As important regulators of developmental and adult processes in metazoans, Fibroblast Growth Factor (FGF) proteins are potent signaling molecules whose activities must be tightly regulated.
Stathopoulos, Angelike, Tulin, Sarah
core   +4 more sources

Quadruple osteotomy: A simple approach to treat “O” deformity in hypophosphatemic rickets

Journal of Orthopedics, Traumatology and Rehabilitation, 2018
Multiple deformities of femur and tibia in a child are known to occur in various conditions such as multiple hereditary exostosis, polyostotic fibrous dysplasia, Osteogenesis imperfecta, achondroplasia, multiple epiphyseal dysplasia, and rickets.
Alok Chandra Agarwal, Bikram Kesari Kar, Harsal Sakale, Avinash Kumar, Rudra Thakur   +4 more
doaj   +1 more source

Mutation update: Variants of the ENPP1 gene in pathologic calcification, hypophosphatemic rickets, and cutaneous hypopigmentation with punctate keratoderma

, 2022
Douglas Ralph, Michael A. Levine, Gabriele Richard, Michelle M. Morrow, Elizabeth K. Flynn, Jouni Uitto, Qiaoli Li   +6 more
openalex   +2 more sources

Molecular analysis of enthesopathy in a mouse model of hypophosphatemic rickets [PDF]

, 2018
Eva S. Liu, Janaina S. Martins, Wanlin Zhang, Marie B. Demay   +3 more
openalex   +1 more source

FAM20C Functions Intracellularly Within Both Ameloblasts and Odontoblasts In Vivo [PDF]

, 2013
FAM20C, also known as Golgi casein kinase (G‐CK), is proposed to be the archetype for a family of secreted kinases that phosphorylate target proteins in the Golgi and in extracellular matrices, but FAM20C serving an extracellular function is ...
Al-Hashimi, Brunati, Chan, Delgado, Duncan, Feng, Fincham, Ishikawa, Kawasaki, Nadanaka, Nalbant, O'Sullivan, Ryu, Simmer, Simpson, Tagliabracci, Tagliabracci, Wang, Wang, Yamakoshi   +19 more
core   +1 more source

Vitamin D: pharmacology and clinical challenges in oral health care [PDF]

, 2019
Vitamin D is a hormone, produced endogenously through cutaneous transformation of 7-dehydrocholesterol by UVB-irradiation with skeletal and non-skeletal functions and could be involved in oral health conditions especially periodontitis.
Antoun Reyad, Ayman, Girgis, Eriny
core